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Phendimetrazine

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Identification
Molecular formula
C18H21N
CAS number
634-03-7
IUPAC name
N,N-dimethyl-3-phenyl-indan-1-amine
State
State

Phendimetrazine is typically found as a solid at room temperature. It is predominantly handled as a powder or as a component in tablet form within the pharmaceutical industry.

Melting point (Celsius)
57.00
Melting point (Kelvin)
330.15
Boiling point (Celsius)
280.00
Boiling point (Kelvin)
553.15
General information
Molecular weight
243.37g/mol
Molar mass
243.3570g/mol
Density
1.0312g/cm3
Appearence

Phendimetrazine generally appears as a white crystalline powder. It may also be found in tablet form as a pharmaceutical preparation. Its pure form is often colorless, but it can appear with a slight color due to impurities or as a result of formulation with other ingredients in medicinal products.

Comment on solubility

Solubility of N,N-dimethyl-3-phenyl-indan-1-amine

N,N-dimethyl-3-phenyl-indan-1-amine, with the chemical formula C17H20N, is a compound that exhibits some intriguing characteristics regarding its solubility.

Solubility Characteristics

The solubility of this compound can be influenced by several factors:

  • Polarity: The presence of the amine group can enhance solubility in polar solvents to some extent, but its large hydrophobic aromatic structure may limit extensive solubilization.
  • Temperature: As with many organic compounds, solubility can increase with temperature. Higher temperatures often facilitate greater solubility in organic solvents.
  • Solvent Type: This compound is generally soluble in organic solvents such as ethanol, methanol, and dichloromethane, while solubility in water is expected to be quite low due to the hydrophobic nature of the indan and phenyl groups.

In summary, while N,N-dimethyl-3-phenyl-indan-1-amine displays significant solubility in organic solvents, it is relatively insoluble in water, highlighting the classic balance between hydrophilic and hydrophobic characteristics in organic compounds.

Interesting facts

Interesting Facts about N,N-dimethyl-3-phenyl-indan-1-amine

N,N-dimethyl-3-phenyl-indan-1-amine is a fascinating compound that belongs to the family of indanamines. This class of compounds is often associated with various biological activities and has gained attention in both pharmaceutical and chemical research. Here are some intriguing aspects of this compound:

  • Pharmaceutical Relevance: Compounds like N,N-dimethyl-3-phenyl-indan-1-amine have potential applications in medicinal chemistry. They are studied for their ability to interact with biological targets, making them candidates for drug development.
  • Structure-Activity Relationship (SAR): The unique structure of this compound, featuring an indan core with a phenyl group and dimethylamino substitution, opens up avenues for understanding how modifications to molecular structures can influence biological activity.
  • Synthetic Versatility: The synthesis of N,N-dimethyl-3-phenyl-indan-1-amine showcases the versatility of organic synthesis techniques. Chemists often employ various strategies, such as condensation reactions and amination, to create similar indanamine derivatives.
  • Research Interest: Due to its structural complexity, N,N-dimethyl-3-phenyl-indan-1-amine has attracted interest in synthetic and medicinal chemistry. Researchers are exploring its properties and reactions to discover new applications.
  • Cross-disciplinary Applications: Beyond medicinal uses, this indanamine might find its place in materials science, particularly in the design of new organic materials or sensors thanks to its unique electronic properties.

The study of compounds like N,N-dimethyl-3-phenyl-indan-1-amine exemplifies the interaction between chemistry and pharmacology, encouraging future discoveries and innovations in the field. As scientists continue to explore the properties of such compounds, the potential for groundbreaking applications remains vast.

Synonyms
DIMEFADANE
5581-40-8
Dimefadano
N,N-Dimethyl-3-phenyl-1-indanamine
SK&F 1340
N,N-dimethyl-3-phenyl-2,3-dihydro-1H-inden-1-amine
SKF-1340
1H-Inden-1-amine, 2,3-dihydro-N,N-dimethyl-3-phenyl-
8P2F16YH55
Dimethyl fandane
Dimefadanum
Dimefadane [USAN:INN]
Dimefadanum [INN-Latin]
Dimefadano [INN-Spanish]
CHEMBL541549
SKF 1340
1-Indanamine, N,N-dimethyl-3-phenyl-
BRN 3322336
UNII-8P2F16YH55
N,N-Dimethyl-3-phenyl-1-indanylamin
DIMEFADANE [INN]
Dimefadane (USAN/INN)
DIMEFADANE [USAN]
N,N-Dimethyl-3-phenyl-1-indanylamin [IUPAC]
4-12-00-03412 (Beilstein Handbook Reference)
SCHEMBL122614
CHEMBL1190753
DTXSID60863572
CHEBI:177652
BDBM50021234
SK&F-1340
NS00008960
D03831
Dimethyl-(3-phenyl-indan-1-yl)-amine; hydrochloride
Q27270840