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Amsacrine

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Identification
Molecular formula
C21H19N3O3
CAS number
51264-14-3
IUPAC name
N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine
State
State

Amsacrine is a solid at room temperature. Due to its crystalline nature, it maintains a stable structure and does not flow like liquids or gases under standard conditions.

Melting point (Celsius)
228.00
Melting point (Kelvin)
501.15
Boiling point (Celsius)
167.00
Boiling point (Kelvin)
440.15
General information
Molecular weight
393.46g/mol
Molar mass
393.4550g/mol
Density
1.3400g/cm3
Appearence

Amsacrine is typically a yellow to orange crystalline solid. Its color can slightly vary depending on the purity and form, but it generally presents as a bright, noticeable pigment, consistent with its aromatic structure.

Comment on solubility

Solubility of N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine

The solubility of N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine in various solvents is quite intriguing due to its complex molecular structure. Understanding its solubility characteristics is essential for applications in chemistry and pharmaceuticals. Here are some key points:

  • Polar Solvents: This compound tends to exhibit better solubility in polar solvents such as water and methanol. The presence of amine groups enhances its ability to interact with polar solvents through hydrogen bonding.
  • Non-Polar Solvents: In contrast, its solubility in non-polar solvents like hexane is negligible. The hydrophobic regions within the molecule make it less compatible with non-polar environments.
  • Temperature Dependence: Solubility may vary with temperature; generally, increasing temperature can enhance solubility in polar solvents.
  • pH Sensitivity: The solubility can also be affected by the pH of the solution, as the protonation state of the amine groups changes, influencing their interaction with solvent molecules.

As a result, it’s often stated that "the solubility of such compounds cannot be generalized and requires careful analysis". Each solvent system and environmental condition could significantly alter the solubility behavior, underscoring the importance of experimental validation in practical applications. Therefore, researchers must pay close attention to these factors when working with N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine.

Interesting facts

Interesting Facts about N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine

N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine is a fascinating compound that showcases the intersection of organic chemistry and medicinal applications. This compound belongs to a broader category of polynitro compounds, which are known for their unique biological activities and potential therapeutic uses.

Key Features

  • Structure Diversity: The compound features a distinctive structure that includes an acridine backbone, which is known for its usefulness in a variety of chemical environments.
  • Biological Significance: Acridine derivatives have been widely studied for their antimicrobial, anti-cancer, and anti-viral properties, making this compound a subject of interest for drug development.
  • Experimental Applications: Researchers have utilized derivatives like this for their potential to interact with nucleic acids, opening avenues for novel therapies in the fight against cancer and bacterial infections.

Practical Implications

One of the compelling aspects of N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine is its interesting balance of stability and reactivity. This makes it a suitable candidate for further studies in the field of medicinal chemistry. As researchers continue to explore its potential uses, the importance of designing derivatives that maintain desired biological activity while minimizing toxicity cannot be overstated.

In summary, N',N'-dimethyl-N-(3-nitroacridin-9-yl)propane-1,3-diamine is more than just a chemical compound. Its unique structural features and potential biological implications make it a noteworthy subject in the realm of chemical research.

Synonyms
6237-24-7
3-Nitro-9-(dimethylaminopropylamino)acridine
C-257
RM9GPV4GNT
ACRIDINE, 9-((3-(DIMETHYLAMINO)PROPYL)AMINO)-3-NITRO-
1,3-Propanediamine, N,N-dimethyl-N'-(3-nitro-9-acridinyl)-
CCRIS 1976
BRN 0496850
3-Nitro-9-(3'-dimethylaminopropylamino)acridine
UNII-RM9GPV4GNT
C 257
DTXSID70211424
N,N-Dimethyl-N'-(3-nitro-acridin-9-yl)-propane-1,3-diamine
1,3-PROPANEDIAMINE, N1,N1-DIMETHYL-N3-(3-NITRO-9-ACRIDINYL)-
N1,N1-DIMETHYL-N3-(3-NITRO-9-ACRIDINYL)-1,3-PROPANEDIAMINE