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Quinazoline

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Identification
Molecular formula
C12H14N4
CAS number
64-18-6
IUPAC name
N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine
State
State

At room temperature, N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine exists as a crystalline solid. It is typically stable under standard conditions but should be stored in a cool, dry place to maintain its integrity.

Melting point (Celsius)
-24.70
Melting point (Kelvin)
248.45
Boiling point (Celsius)
414.00
Boiling point (Kelvin)
687.15
General information
Molecular weight
160.19g/mol
Molar mass
160.1940g/mol
Density
1.0746g/cm3
Appearence

N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine is typically seen as a crystalline solid, the appearance may vary from white to off-white. These crystals may be either in powdered form or as slightly yellowish aggregated masses.

Comment on solubility

Solubility of N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine

N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine, a compound with a complex structure, exhibits unique solubility characteristics that can be influenced by various factors:

  • Polarity: The presence of nitrogen atoms and other functional groups in the molecular structure indicates a degree of polarity, which may enhance solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds can significantly affect solubility. This compound may engage in hydrogen bonding with solvents, thereby improving solubility.
  • Temperature Dependence: As with many organic compounds, solubility may increase with higher temperatures. Testing solubility at various temperatures could provide valuable insights.
  • pH Sensitivity: The ionization of the amine functional groups can affect solubility in different pH environments, suggesting that solubility might vary with acidity or alkalinity.

While specific solubility data may not be abundantly available, understanding these contributing factors allows researchers to make educated predictions. In summary, the solubility of N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine is likely to be favorable in polar solvents and can vary significantly based on physical and chemical conditions.

Interesting facts

Interesting Facts about N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine

N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine is a fascinating compound that piques the interest of both chemists and pharmacologists alike.
Here are some engaging aspects of this compound:

  • Versatile Structure: This molecule features a quinazoline core, a bicyclic structure that is known for its biological activity. Quinazoline derivatives are often found in drug development, illustrating the compound's potential significance.
  • Biological Implications: Compounds such as this one can exhibit various biological activities including antiviral, anticancer, and antimicrobial properties. Researchers are particularly interested in quinazoline derivatives for their ability to inhibit certain enzymes and pathways within cells.
  • Dual Functionality: The presence of dimethyl and ethane-1,2-diamine groups enhances its potential to interact with a variety of biological molecules, opening avenues for targeted therapies or as a tool in molecular biology.
  • Research Opportunities: The study of this compound could lead to the development of novel pharmaceuticals. It stands at the crossroads of organic chemistry and medicinal applications, providing a rich field for exploration.
  • Futuristic Applications: As drug design evolves, the incorporation of such compounds in new synthetic pathways is essential. Scientists are intrigued by the challenges of optimizing their efficacy and reducing potential side effects.

In conclusion, N',N'-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine is more than just a chemical structure; it represents a focal point of interdisciplinary research where chemistry meets biology in the quest for medical advancements. As we continue to unravel its properties, the potential for innovative applications remains vast.

Synonyms
Quinazoline, 4-((2-(dimethylamino)ethyl)amino)-
3337-87-9
N,N-Dimethyl-N'-quinazolin-4-yl-ethane-1,2-diamine
Quinazoline, 4-[[2-(dimethylamino)ethyl]amino]-
MLS000031555
4-Dimethyl aminoethyl amino quinazoline
SMR000010337
BRN 0746606
SU-13026
EQ7HM4CGV5
Oprea1_599682
Oprea1_673088
CHEMBL1624896
BDBM39575
cid_2789306
DTXSID00186994
HMS1680N16
STK969982
AKOS000536813
4-(2-Dimethylaminoethylamino)quinazoline
N,N-dimethyl-N'-(quinazolin-4-yl)ethane-1,2-diamine
N1,N1-dimethyl-N2-4-quinazolinyl-1,2-ethanediamine
1,2-Ethanediamine, N1,N1-dimethyl-N2-4-quinazolinyl-
dimethyl-[2-(quinazolin-4-ylamino)ethyl]amine;hydrochloride
N'',N''-dimethyl-N-quinazolin-4-ylethane-1,2-diamine;hydrochloride
N'',N''-dimethyl-N-(4-quinazolinyl)ethane-1,2-diamine;hydrochloride
N'',N''-dimethyl-N-quinazolin-4-yl-ethane-1,2-diamine;hydrochloride