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Memantine

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Identification
Molecular formula
C12H21N
CAS number
19982-08-2
IUPAC name
N,N-dimethyladamantan-1-amine
State
State

At room temperature, memantine exists as a solid.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
179.30g/mol
Molar mass
179.3010g/mol
Density
1.2000g/cm3
Appearence

Memantine typically appears as a crystalline powder. It is white to off-white in color, indicating its high purity and lack of contaminants. The crystalline nature of the powder is indicative of its solid state form at room temperature.

Comment on solubility

Solubility of N,N-Dimethyladamantan-1-amine

N,N-Dimethyladamantan-1-amine, with the chemical formula C12H21N, exhibits some intriguing properties when it comes to its solubility.

This compound is primarily insoluble in water due to:

  • Hydrophobicity: The adamantane structure contributes significantly to its hydrophobic character, making it less favorable for interaction with polar solvents like water.
  • Size: The relatively large carbon skeleton hinders the formation of hydrogen bonds with water molecules.

However, N,N-dimethyladamantan-1-amine shows a good solubility profile in organic solvents, characterized by:

  • Compatibility with nonpolar solvents: It is soluble in many organic solvents such as ethanol, dichloromethane, and chloroform.
  • Utilization in organic syntheses: Its solubility in these solvents enhances its effectiveness as a reagent in various organic reactions.

Furthermore, the compound's solubility can be influenced by:

  • Temperature: Increased temperature often enhances solubility in organic solvents.
  • Concentration: At higher concentrations, the solubility limits may vary, affecting its overall behavior.

In conclusion, while N,N-dimethyladamantan-1-amine may lack solubility in water, its behavior in organic solvents opens up a range of possibilities for its application in the chemical field. As noted, "Understanding the solubility of compounds is key to unlocking their potential in various chemical applications."

Interesting facts

Exploring N,N-Dimethyladamantan-1-amine

N,N-Dimethyladamantan-1-amine, often abbreviated as DMAA, is a fascinating compound and a member of the amine class of organic compounds. Here are some engaging facts about this unique molecule:

  • Structure and Stability: This compound is known for its unique adamantane backbone, a highly symmetrical structure that contributes to its remarkable stability and interesting chemical properties.
  • Biochemical Relevance: DMAA has been investigated for its potential as a stimulant. It can influence certain biochemical pathways, stimulating the release of neurotransmitters like norepinephrine, which may improve alertness and focus.
  • Applications in Industry: Beyond its biochemical applications, N,N-dimethyladamantan-1-amine is also utilized in various industrial settings, such as in the production of specialty chemicals and as a starting material for synthesizing other pharmaceutical compounds.
  • Controversial Usage: The use of DMAA as a dietary supplement has sparked debates in the scientific community and among health authorities. While some users report enhanced physical performance, regulatory agencies have raised concerns about its safety, underscoring the need for careful scrutiny and responsible use.
  • Research Insights: Ongoing studies are unveiling more about the pharmacological effects of DMAA, aiming to clarify its mechanism of action and potential therapeutic uses. Researchers are exploring its effects on metabolism and weight loss, making it a compound of interest in modern medicinal chemistry.

As we delve deeper into the world of N,N-dimethyladamantan-1-amine, it is important to remain informed about both the potentials and pitfalls of its applications. Understanding its chemistry not only enriches our knowledge of amines but also invites consideration of the responsible development of compounds with stimulant properties.

Synonyms
3717-40-6
1-Adamantyldimethylamine
N,N-Dimethyl-1-adamantanamine
1-ADAMANTANAMINE, N,N-DIMETHYL-
N,N-Dimethyl-1-adamantylamine
(Dimethylamino)adamantane
BRN 2075898
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine, N,N-dimethyl-
N,N-Dimethyladamantylamine
1-(Dimethylamino)adamantane
N,N-Dimethyltricyclo(3.3.1.1(sup 3,7))decan-1-amine
1-(N,N-Dimethylamino)adamantane
DTXSID00893535
EC 609-335-2
DTXCID601323558
Tricyclo(3.3.1.1(sup 3,7))decan-1-amine, N,N-dimethyl-(9CI)
609-335-2
nfbycnfaxlugbt-uhfffaoysa-n
N,N-dimethyladamantan-1-amine
Tricyclo[3.3.1.13,7]decan-1-amine, N,N-dimethyl-
N,N-Dimethyladamantane-1-amine
dimethylaminoadamantane
Tricyclo(3.3.1.13,7)decan-1-amine, N,N-dimethyl-
MFCD01674012
1-adamantyl-dimethylamine
N,N-dimethyltricyclo[3.3.1.1~3,7~]decan-1-amine
CHEMBL131460
SCHEMBL1075539
STL007694
AKOS006275904
AKOS015955274
FN180798
CS-0368048
NS00011451
Tricyclo[3.3.1.1]decan-1-amine, N,N-dimethyl-