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Memantine hydrochloride

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Identification
Molecular formula
C12H22ClN
CAS number
41100-52-1
IUPAC name
N,N-dimethyladamantan-2-amine;hydrochloride
State
State

At room temperature, memantine hydrochloride is in a solid state. As a pharmaceutical agent, it is administered in this stable solid form, often in tablets or capsules for ease of use.

Melting point (Celsius)
292.00
Melting point (Kelvin)
565.15
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.15
General information
Molecular weight
215.77g/mol
Molar mass
215.7600g/mol
Density
1.0080g/cm3
Appearence

Memantine hydrochloride typically appears as a white to off-white crystalline powder. It is known for its stability and purity, which is essential in its role as a pharmaceutical compound. The powder is soluble in water and other solvents, making it easily usable in various formulations.

Comment on solubility

Solubility of N,N-dimethyladamantan-2-amine;hydrochloride

N,N-dimethyladamantan-2-amine;hydrochloride, a salt form of N,N-dimethyladamantan-2-amine, displays interesting solubility characteristics that are significant for its applications. As a hydrochloride salt, it is typically soluble in polar solvents.

  • Solubility in Water: This compound is generally soluble in water due to the ionic nature imparted by the hydrochloride formation. The presence of the amine functional group enhances interaction with water molecules.
  • Solvent Compatibility: It may also exhibit solubility in various aqueous organic solvents, such as alcohols, although solubility can vary depending on the structure and additional substituents.
  • pH Dependence: The solubility is pH-dependent. Under acidic conditions, the protonation of the amine enhances solubility, while in neutral or basic conditions, it may precipitate.

It’s essential to always consider the specific conditions such as temperature and pH, as they can influence the overall solubility profile. Understanding the solubility for this compound is crucial, not only for laboratory handling but also for its potential therapeutic applications.

Interesting facts

Exploring N,N-Dimethyladamantan-2-amine Hydrochloride

N,N-Dimethyladamantan-2-amine hydrochloride is a fascinating compound that belongs to the class of amines and demonstrates intriguing properties and potential applications. Here are some captivating facts about this chemical compound:

  • Unique Structure: This compound features an adamantane core, a well-known polycyclic structure that is often referred to as a "diamond-like" hydrocarbon due to its distinctive stability and rigidity.
  • Biological Activity: N,N-Dimethyladamantan-2-amine is studied for its potential effects on the central nervous system, making it of interest in neuropharmacology.
  • Pharmaceutical Relevance: Compounds with an adamantane structure have been used in drug design and development, including for antiviral medications such as amantadine.
  • Research Applications: Ongoing studies are looking into its possible applications in treating neurodegenerative diseases, highlighting the importance of researching amine derivatives.

This compound exemplifies the combination of structural complexity and potential therapeutic utility, making it a rich area for scientific inquiry. As *scientists* and *chemistry students*, delving deeper into the characteristics and reactions of such compounds opens doors to innovation in medicinal chemistry.

Synonyms
10535-34-9
2-ADAMANTANAMINE, N,N-DIMETHYL-, HYDROCHLORIDE
2-Dimethylaminoadamantane hydrochloride
DTXSID20147087
Tricyclo(3.3.1.1(sup 3,7))decan-2-amine, N,N-dimethyl-, hydrochloride
DTXCID7069578
Tricyclo(3.3.1.1(sup 3,7))decan-2-amine, N,N-dimethyl-, hydrochloride (9CI)
N,N-dimethyl-2-adamantanamine hydrochloride
N,N-dimethyladamantan-2-amine;hydrochloride
N,N-Dimethyl-2-adamantanaminehydrochloride