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2-(Dimethylamino)pyridine

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Identification
Molecular formula
C7H10N2
CAS number
1122-58-3
IUPAC name
N,N-dimethylpyridin-2-amine
State
State

At room temperature, 2-(Dimethylamino)pyridine is a solid.

Melting point (Celsius)
110.00
Melting point (Kelvin)
383.15
Boiling point (Celsius)
211.10
Boiling point (Kelvin)
484.25
General information
Molecular weight
122.18g/mol
Molar mass
122.1770g/mol
Density
0.9655g/cm3
Appearence

2-(Dimethylamino)pyridine appears as crystalline needles or powder. It may be colorless or exhibit a yellowish tint.

Comment on solubility

Solubility of N,N-dimethylpyridin-2-amine

N,N-dimethylpyridin-2-amine, with the chemical formula C7H10N2, exhibits noteworthy solubility characteristics in various solvents. It is primarily soluble in:

  • Polar solvents: It demonstrates high solubility in water due to its ability to form hydrogen bonds.
  • Alcohols: Compounds like methanol and ethanol also provide an excellent medium for dissolution, enhancing its reactivity.
  • Aromatic hydrocarbons: It shows moderate solubility in solvents such as toluene, exploiting favorable pi-pi stacking interactions.

However, its solubility profile may vary significantly depending on factors such as:

  1. Temperature: An increase in temperature generally improves solubility.
  2. Concentration: At higher concentrations, solubility may deviate from ideal behavior.
  3. pH levels: The presence of acidic or basic conditions can alter the ionization state of the molecule, thus affecting its solubility.

In summary, N,N-dimethylpyridin-2-amine’s solubility is quite favorable, making it a versatile compound in various chemical applications. As highlighted, the interaction with solvents is paramount, demonstrating that "like dissolves like" is an essential principle in understanding its solubility behavior.

Interesting facts

Interesting Facts about N,N-Dimethylpyridin-2-amine

N,N-Dimethylpyridin-2-amine, often referred to as a derivative of pyridine, belongs to a class of compounds known for their diverse chemical behavior and utility in various fields. Here are some intriguing aspects of this compound:

  • Structure and Functionality: The presence of both a pyridine ring and amine functionality gives N,N-dimethylpyridin-2-amine unique properties. The methyl groups enhance its nucleophilicity, making it attractive for various reactions.
  • Reactivity: This compound is known to engage in reactions typical for amines, such as alkylation and acylation. Its reactivity can be harnessed in numerous synthetic applications, particularly in pharmaceutical chemistry.
  • Biological Significance: Compounds related to pyridine often exhibit biological activity, providing potential leads in drug discovery. N,N-dimethylpyridin-2-amine could serve as a building block for pharmaceuticals targeting various diseases.
  • Applications: Beyond the pharmaceutical realm, this compound is also used in the synthesis of agrochemicals and as a building block in material science, demonstrating its versatility.
  • Historical Context: Pyridine derivatives have a rich history in chemistry, with early studies linking them to vital processes in biochemistry, paving the way for modern organic synthesis.

In summary, N,N-dimethylpyridin-2-amine is more than just a chemical species; it is a versatile building block with broad applications in science and industry. As noted by chemists, "The beauty of chemistry lies in the potential of simple structures to lead to complex, functional materials."

Synonyms
2-Dimethylaminopyridine
5683-33-0
N,N-Dimethylpyridin-2-amine
2-(Dimethylamino)pyridine
2-Dimethylaminopyridin
Pyridine, 2-(dimethylamino)-
Dimethylamino-2 pyridine
N,N-Dimethyl-2-pyridinamine
PYRIDINE, 2-DIMETHYLAMINO-
(Dimethylamino)-2-pyridine
EINECS 227-147-5
NSC 93902
UNII-18Q95U3Z8H
BRN 0110353
2,6-Dimethyl-3-pyridinylamine
2-Pyridinamide, N,N-dimethyl-
18Q95U3Z8H
NSC-93902
DTXSID9022231
5-22-08-00287 (Beilstein Handbook Reference)
N,N-DIMETHYLPYRIDIN-2-YLAMINE
DTXCID902231
2-Pyridinamide, N,N-dimethyl-(9CI)
inchi=1/c7h10n2/c1-9(2)7-5-3-4-6-8-7/h3-6h,1-2h
pshkmpussfxuia-uhfffaoysa-n
dimethylaminopyridine
2-Pyridinamine, N,N-dimethyl-
MFCD00006261
2-dimethylamino pyridine
Dimethyl-pyridin-2-yl-amine
Dimethylaminopyridin
Pyridinamine, N,N-dimethyl-
dimethylamino pyridine
dimethlaminopyridine
Dimethyaminopyridine
dimethylaminopyndine
dimethlyaminopyridine
dimethylaminopiridine
dimethylaninopyridine
dimethyamino pyridine
dimethylamino-pyridine
dimethylamino~pyridine
(dimethylamino)pyridine
n,n-dimethylamino pyridine
SCHEMBL364
(n,n-dimethylamino)pyridine
2-Pyridinamine,N-dimethyl-
N-(2-Pyridyl)dimethylamine
(N,N- dimethylamino)pyridine
WLN: T6NJ BN1&1
N,N-Dimethyl-2-pyridinamine #
2-(N,N-dimethylamino)-pyridine
Methyl-pyridin-2-yl-methyl-amine
2-(Dimethylamino)pyridine, 97%
Methyl-pyridin-2-yl -methyl-amine
NSC93902
AKOS005206861
SB53029
AS-59067
BP-10156
PD148427
SY049629
DB-052973
A8125
CS-0112703
D1680
NS00033587
D89909
EN300-7040398
Q27252024
2-(Dimethylamino)pyridine; N,N-Dimethylpyridin-2-amine