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O-[(2-methyl-1-naphthyl)methyl]hydroxylamine

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Identification
Molecular formula
C12H13NO
CAS number
83964-52-3
IUPAC name
O-[(2-methyl-1-naphthyl)methyl]hydroxylamine
State
State

The compound is a solid at room temperature, appearing as crystals.

Melting point (Celsius)
92.00
Melting point (Kelvin)
365.15
Boiling point (Celsius)
381.50
Boiling point (Kelvin)
654.65
General information
Molecular weight
187.24g/mol
Molar mass
187.2400g/mol
Density
1.1670g/cm3
Appearence

The compound is typically a solid at room temperature, with an off-white to pale yellow color. It is crystalline in nature.

Comment on solubility

Solubility of O-[(2-methyl-1-naphthyl)methyl]hydroxylamine

The solubility of O-[(2-methyl-1-naphthyl)methyl]hydroxylamine is influenced by several factors, making it a compound of interest in the study of organic chemistry. Here are some key points regarding its solubility:

  • Polar and Nonpolar Characteristics: This compound exhibits both polar and nonpolar characteristics, a result of the naphthyl group and the hydroxylamine functional group. This dual nature affects its interaction with solvents.
  • Solvent Compatibility: It is likely soluble in a variety of organic solvents such as ethanol, acetone, and dichloromethane. However, its solubility in water is expected to be limited due to hydrophobic interactions from the naphthyl moiety.
  • pH Influence: The solubility may further vary with pH, as hydroxylamines can ionize, impacting their solubility in aqueous solutions.
  • Temperature Impact: As with many organic compounds, increasing temperature can enhance solubility due to increased molecular motion.

In summary, while O-[(2-methyl-1-naphthyl)methyl]hydroxylamine is primarily soluble in organic solvents, factors such as temperature, solvent choice, and pH play significant roles in its total solubility, making it an intriguing subject for further investigation.

Interesting facts

Interesting Facts about O-[(2-methyl-1-naphthyl)methyl]hydroxylamine

O-[(2-methyl-1-naphthyl)methyl]hydroxylamine is a fascinating organic compound that is widely recognized for its role in organic synthesis and pharmaceuticals. As a derivative of hydroxylamine, it offers a unique set of properties and functionalities that make it beneficial in various chemical reactions.

Key Features

  • Structure and Reactivity: The compound contains a naphthalene moiety, which contributes to its stability and reactivity. The presence of the hydroxylamine functional group enhances its nucleophilic capacity, making it an ideal candidate for many chemical transformations.
  • Applications: O-[(2-methyl-1-naphthyl)methyl]hydroxylamine is used in photoinduced reactions, where it plays a critical role in the formation of various organic intermediates. This makes it a valuable tool in synthetic organic chemistry.
  • Biochemical Relevance: Hydroxylamines, in general, are of interest for their potential in the design of anticancer agents and in the development of imaging techniques in biochemistry.

Citation from the Field

It is often stated that "the ability to manipulate functional groups in organic molecules is fundamental to modern chemistry." O-[(2-methyl-1-naphthyl)methyl]hydroxylamine exemplifies this notion by allowing chemists to explore complex pathways in organic synthesis.

Considerations in Use

  • Synthesis Techniques: The synthesis of this compound typically involves the careful reaction of a naphthol derivative with hydroxylamine under controlled conditions.
  • Handling Procedures: As with many organic compounds, safety precautions are necessary when handling O-[(2-methyl-1-naphthyl)methyl]hydroxylamine, including using appropriate personal protective equipment (PPE).

In conclusion, O-[(2-methyl-1-naphthyl)methyl]hydroxylamine not only adds to the rich tapestry of organic chemistry but also opens pathways for further research and application in the field of medicinal chemistry and beyond. Its multifaceted utility continues to inspire chemists around the world.

Synonyms
NAFOMINE
Nafomine [INN]
46263-35-8
UNII-26C7FUA5S7
26C7FUA5S7
O-((2-METHYL-1-NAPHTHYL)METHYL)HYDROXYLAMINE
RefChem:164406
O-[(2-methylnaphthalen-1-yl)methyl]hydroxylamine
Nafomina
SCHEMBL8600936
CHEMBL2110690
DTXSID40866122
AKOS006272564
NS00121131
Q27254085