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O-Methylhydroxylamine

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Identification
Molecular formula
CH5NO
CAS number
946-48-5
IUPAC name
O-methylhydroxylamine
State
State

At room temperature, O-Methylhydroxylamine exists as a liquid.

Melting point (Celsius)
-3.00
Melting point (Kelvin)
270.15
Boiling point (Celsius)
102.00
Boiling point (Kelvin)
375.15
General information
Molecular weight
47.06g/mol
Molar mass
47.0640g/mol
Density
0.9308g/cm3
Appearence

O-Methylhydroxylamine typically appears as a colorless to pale yellow liquid. It is usually encountered in solution since it is readily soluble in water and many organic solvents.

Comment on solubility

Solubility of O-methylhydroxylamine (CH5NO)

O-methylhydroxylamine is known for its unique solubility characteristics, making it an interesting compound in chemical studies. Its solubility can be summarized as follows:

  • Solvent Compatibility: O-methylhydroxylamine is highly soluble in polar solvents, particularly in water and alcohols.
  • Solvent Interaction: The presence of the hydroxyl group (-OH) enhances its ability to interact with water molecules through hydrogen bonding, which plays a significant role in its solubility.
  • Temperature Influence: Like many small organic compounds, its solubility may increase with rising temperature, allowing more of the compound to dissolve.

It is often observed that:

  • Many amines, including aldehyde-derived derivatives like O-methylhydroxylamine, exhibit substantial solubility in polar solvents due to their ability to engage in hydrogen bonding.
  • The molecular structure contributes to its high solubility in water, which is critical for various applications in organic synthesis and analytical chemistry.

In conclusion, O-methylhydroxylamine demonstrates excellent solubility properties, particularly in polar media, making it a valuable compound in chemical research and applications.

Interesting facts

Interesting Facts about O-methylhydroxylamine

O-methylhydroxylamine is a fascinating compound that has garnered attention due to its roles in various chemical reactions and applications. Here are some notable aspects:

  • Chemical Reactivity: O-methylhydroxylamine is widely used as a reagent in organic synthesis. It is particularly effective in the conversion of carbonyl compounds to oximes, enhancing the versatility of synthetic pathways.
  • Analytical Chemistry: The compound's ability to form stable oximes makes it valuable in analytical chemistry, especially in identifying and quantifying aldehydes and ketones.
  • Pharmaceutical Applications: O-methylhydroxylamine has been explored for its potential in medicinal chemistry, where it can contribute to the development of new drug candidates, particularly those targeting neurological disorders.
  • Environmental Impact: The compound's interaction with atmospheric chemicals has been studied, contributing to our understanding of environmental processes and pollutant transformations.
  • Safety and Handling: While O-methylhydroxylamine is generally considered safe when handled properly, it is always crucial to follow safety protocols due to its reactivity and potential hazards.

In summary, O-methylhydroxylamine exemplifies the intricate relationships between chemical structures and their functions in both synthetic and analytical contexts. Its practicality extends beyond the lab, influencing fields such as environmental science and pharmacology.

Synonyms
O-METHYLHYDROXYLAMINE
Methoxyamine
67-62-9
Methoxylamine
Hydroxylamine, O-methyl-
Hydroxylamine methyl ether
alpha-Methylhydroxylamine
HSDB 2883
CH3ONH2
NCI-C60060
UNII-9TZH4WY30J
EINECS 200-660-1
BRN 1098249
METHOXYAMINE [MI]
9TZH4WY30J
METHOXYAMINE [WHO-DD]
DTXSID8043862
GMPKIPWJBDOURN-UHFFFAOYSA-
4-01-00-01252 (Beilstein Handbook Reference)
O-METHYLHYDROXYLAMINE [HSDB]
methane, O-aminohydroxy-
methoxy amine
N-methoxyamine
OMethylhydroxylamine
Amidogen, methoxy-
MeONH2
NH2OMe
O-methyl hydroxylamine
O-methyl-hydroxylamine
O-methylhydroxyl amine
Hydroxylamine, Omethyl
alphaMethylhydroxylamine
Spectrum_001650
O-methyl hydroxyl amine
TRC102 Base
SpecPlus_000744
Spectrum2_000914
Spectrum3_000765
Spectrum4_001103
Spectrum5_001275
BSPBio_002410
KBioGR_001546
KBioSS_002130
DivK1c_000600
DivK1c_006840
SPBio_000788
CHEMBL1213633
DTXCID6023862
KBio1_000600
KBio1_001784
KBio2_002130
KBio2_004698
KBio2_007266
KBio3_001630
CHEBI:192842
NINDS_000600
DTXSID801316171
BBL028003
STL373472
AKOS009087974
DB06328
IDI1_000600
NCGC00178666-01
BP-31110
NS00009844
F16476
BRD-K79277568-003-04-7
Q18344129
199807-37-9