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p-Tolylurea

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Identification
Molecular formula
C8H10N2O
CAS number
622-57-3
IUPAC name
p-tolylurea
State
State

At room temperature, p-Tolylurea is in a solid state.

Melting point (Celsius)
215.00
Melting point (Kelvin)
488.15
Boiling point (Celsius)
275.00
Boiling point (Kelvin)
548.15
General information
Molecular weight
150.18g/mol
Molar mass
150.1820g/mol
Density
1.1900g/cm3
Appearence

p-Tolylurea is typically a crystalline solid, often found as colorless or white crystals. It may appear slightly off-white if impure or slightly aged due to environmental exposure.

Comment on solubility

Solubility of p-tolylurea

p-tolylurea, with the chemical formula C8H10N2O, exhibits interesting solubility characteristics that are crucial for various applications in chemical processes.

Solubility Traits

The solubility of p-tolylurea can be summarized as follows:

  • Solvent Interaction: p-tolylurea is generally soluble in polar solvents such as water and alcohols due to the presence of the urea functional group.
  • Non-Polar Solvents: It shows reduced solubility in non-polar solvents, illustrating a distinct preference for hydrogen bonding with polar molecules.
  • Temperature Influence: The solubility may increase with temperature, which is a common behavior among organic compounds.

It is essential to note that "p-tolylurea's solubility is governed by both temperature and the nature of the solvent", which ultimately affects its utilization in chemical reactions and formulations. Understanding its solubility profile can aid significantly in optimizing conditions for synthesis and application.

Interesting facts

Interesting Facts about p-Tolylurea

p-Tolylurea, also known as p-toluamide, is a fascinating organic compound that belongs to the class of ureas. It is notable for its various applications in biological and chemical research due to its unique structure and properties. Here are some intriguing aspects of p-tolylurea:

  • Key Structural Features: p-Tolylurea contains a tolyl group, which is a derivative of toluene. This structure enhances its solubility in organic solvents and contributes to its reactivity.
  • Biological Relevance: Research has shown that p-tolylurea can exhibit interesting biological activities. It has been studied for its potential as an antihypertensive agent and in the development of various pharmaceuticals.
  • Research Applications: Due to its urea functional group, this compound plays a significant role in organic synthesis and serves as an important intermediate in the production of pesticides and herbicides.
  • Exploration of Derivatives: Scientists have synthesized various derivatives of p-tolylurea to enhance its efficacy and broaden its applications, sparking ongoing research into its derivatives for medicinal purposes.
  • Environmental Impact: As with many organic chemicals, understanding the environmental impact and degradation pathways of p-tolylurea is crucial, particularly in contexts involving agricultural chemical usage.

In summary, p-tolylurea is more than just a simple organic compound; it represents a bridge between classical organic chemistry and modern pharmaceutical research. Its versatility makes it a compelling subject for study, with ongoing research uncovering new potentials in various fields.

Synonyms
P-TOLYLUREA
(4-Methylphenyl)urea
4-Tolylurea
N-(4-Methylphenyl)urea
p-Tolyurea
CCRIS 4875
para-Tolylurea
1-p-tolylurea
EINECS 210-739-2
JCJ6M4A3I5
BRN 2208088
DTXSID7021366
AI3-52050
TOLYLUREA, P-
NSC-66557
UNII-JCJ6M4A3I5
4-12-00-01923 (Beilstein Handbook Reference)
DTXCID901366
UREA, N-(4-METHYLPHENYL)-
1(4-tolyl)urea
dmshkwhlxndust-uhfffaoysa-n
622-51-5
1-(p-Tolyl)urea
4-Methylphenylurea
p-Tolylcarbamide
Urea, p-tolyl-
Urea, (4-methylphenyl)-
1-(4-methylphenyl)urea
p-Tolycarbamide
p-methylphenylurea
NCI-C02153
NSC 66557
3-p-tolylurea
N-(p-tolyl)urea
MFCD00025433
N-P-TOLYLUREA
Maybridge4_001877
WLN: ZVMR D1
SCHEMBL81433
CHEMBL3187464
HMS1526F07
NSC66557
Tox21_200832
STL124178
AKOS000113516
BS-3831
SB76023
NCGC00177164-01
NCGC00177164-02
NCGC00258386-01
CAS-622-51-5
DB-054107
CS-0096273
NS00034980
T0328
EN300-16680
D92325
BRD-K53876482-001-01-9
Z56754677