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Brompheniramine

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Identification
Molecular formula
C16H20BrNO
CAS number
86-22-6
IUPAC name
phenyl-[2-(2-piperidin-1-ium-1-ylpropoxy)phenyl]methanone;bromide
State
State

At room temperature, Brompheniramine is a solid. It can exist as a crystalline powder and is often prepared in pharmaceutical formulations as tablets or liquid solutions.

Melting point (Celsius)
118.00
Melting point (Kelvin)
391.15
Boiling point (Celsius)
287.20
Boiling point (Kelvin)
560.35
General information
Molecular weight
435.29g/mol
Molar mass
435.2860g/mol
Density
1.3400g/cm3
Appearence

Brompheniramine is typically obtained as white to off-white crystals or crystalline powder. It can also be found in the form of tablets or a clear liquid solution when used in pharmaceutical preparations.

Comment on solubility

Solubility of Phenyl-[2-(2-piperidin-1-ium-1-ylpropoxy)phenyl]methanone Bromide (C16H20BrNO)

The solubility of Phenyl-[2-(2-piperidin-1-ium-1-ylpropoxy)phenyl]methanone bromide can be intriguing due to its complex structure, which can impart unique properties in solution. Understanding its solubility is essential for various applications in both synthetic and biological chemistry.

Factors Affecting Solubility

Several factors can influence the solubility of this compound:

  • Polarity: The presence of polar functional groups can enhance solubility in polar solvents, whereas non-polar components may favor solubility in organic solvents.
  • Ionization: As this compound contains a piperidinium group, it can act as an ionic species in solution, which may increase solubility in aqueous media.
  • Temperature: Generally, higher temperatures may increase solubility for most ionic and polar compounds.

General Observations

In general, compounds with similar characteristics are often:

  • Soluble in water: due to ionic interactions.
  • Soluble in organic solvents: such as ethanol or dichloromethane, if non-polar hydrophobic regions dominate.
  • Compound stability: may affect overall solubility; degradation could limit how much can dissolve.

In conclusion, while we can predict certain solubility behaviors based on the structure and the aforementioned factors, actual solubility experiments are essential for precise data. It's always crucial to follow up theoretical insights with practical assessments to understand the solubility of this compound thoroughly.

Interesting facts

Interesting Facts about Phenyl-[2-(2-piperidin-1-ium-1-ylpropoxy)phenyl]methanone Bromide

The compound known as Phenyl-[2-(2-piperidin-1-ium-1-ylpropoxy)phenyl]methanone bromide is an intriguing addition to the realm of organic chemistry, particularly in the field of medicinal chemistry due to its potential biological activities.

Key Insights

  • Quaternary Ammonium Ion: This compound features a piperidinium moiety, which is a positively charged nitrogen atom in a heterocyclic ring. This property contributes to its interactions within biological systems.
  • Drug Design: The structure of this compound makes it valuable in the design of pharmacological agents, as its bulky phenyl groups can enhance receptor affinity and selectivity.
  • Versatile Applications: Compounds of this nature may be investigated for therapeutic uses, such as anti-cancer, anti-infective, or neuroprotective activities, given the diverse action of similar structures.
  • Synthesis Potential: The synthesis of such compounds often involves multi-step organic reactions, allowing chemists to explore innovative synthetic techniques and methodologies.

As we delve deeper into the biosynthetic pathways, the study of this bromide salt allows researchers to understand how the properties of ionic species can affect biological uptake and activity. Whether impacting cell membrane integrity or binding affinities, the study of this compound sheds light on the intricate dance between structure and function.

In the words of an eminent chemist, "Understanding complex compounds opens doors to revolutionary treatments that can alter the course of diseases." Thus, exploring Phenyl-[2-(2-piperidin-1-ium-1-ylpropoxy)phenyl]methanone bromide could potentially lead to exciting advances in medicinal chemistry.

Synonyms
2-(2-Piperidinopropoxy)benzophenone hydrobromide
10571-21-8
BENZOPHENONE, 2-(2-PIPERIDINOPROPOXY)-, HYDROBROMIDE