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Benproperine Hydrochloride

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Identification
Molecular formula
C21H24ClNO3
CAS number
911-68-2
IUPAC name
phenyl-[3-(piperidin-1-ium-1-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methanone;chloride
State
State

At room temperature, benproperine hydrochloride is in a solid, crystalline state. It is typically available in its salt form as a hydrochloride to enhance its stability and ease of formulation for medicinal use.

Melting point (Celsius)
105.00
Melting point (Kelvin)
378.00
Boiling point (Celsius)
200.00
Boiling point (Kelvin)
473.00
General information
Molecular weight
343.88g/mol
Molar mass
343.8350g/mol
Density
1.2400g/cm3
Appearence

Benproperine hydrochloride appears as a white to off-white crystalline powder. It is generally presented in its hydrochloride salt form to improve solubility and stability. The powder is hygroscopic and absorbs moisture from the environment.

Comment on solubility

Solubility of Phenyl-[3-(piperidin-1-ium-1-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methanone; Chloride

The solubility of phenyl-[3-(piperidin-1-ium-1-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methanone; chloride can be influenced by various factors, including its ionic nature and the presence of hydroxyl or amine groups. Here are some key points regarding its solubility:

  • Ionic Interaction: Being a chloride salt, it is likely to be soluble in polar solvents due to ionic interactions. This can enhance solubility in water.
  • Hydrophobic Characteristics: The phenyl and benzodioxin structures contribute a degree of hydrophobicity, which can influence solubility in non-polar solvents, potentially reducing solubility in aqueous environments.
  • pH Sensitivity: The presence of the piperidinium group implies that solubility may be affected by the pH of the solution. The compound may exhibit increased solubility at lower pH levels, making it more soluble in acidic conditions.
  • Temperature Dependence: As with many organic compounds, solubility may increase with temperature, enabling better dissolution in solvents when heated.

Overall, while expectations can be made regarding its solubility profile, the exact solubility of phenyl-[3-(piperidin-1-ium-1-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methanone; chloride would ideally be assessed experimentally to understand its behavior in various solvents, especially for applications in biological or pharmaceutical contexts.

Interesting facts

Interesting Facts about Phenyl-[3-(piperidin-1-ium-1-ylmethyl)-2,3-dihydro-1,4-benzodioxin-6-yl]methanone; Chloride

This intriguing compound is a testament to the fascinating intersections of organic chemistry and medicinal research. Delving into its characteristics reveals a host of interesting aspects:

  • Structural Complexity: The compound features a sophisticated structure that includes a piperidin-1-ium moiety and a benzodioxin component, showcasing how varied organic structures can be synthesized through creative chemical design.
  • Potential Applications: Compounds like this often serve as useful intermediates in pharmaceutical chemistry. The unique functional groups suggest potential bioactivity, which can be explored for therapeutic applications.
  • Charge Interaction: The presence of a quaternary ammonium ion (piperidin-1-ium) indicates a strong ionic character, which may influence its solubility and interaction with biological systems.
  • Pharmacological Interest: The benzodioxin part of the structure is known for its activity in various pharmacological contexts, potentially contributing to the compound's biological properties.
  • Research Opportunities: Given its intricate structure and possible functionality, this compound is ripe for investigation in medicinal chemistry, particularly in the realms of drug design and synthesis.

As researchers dive deeper, they may discover novel pathways for synthesizing this compound or uncover new biological activities that could lead to advances in therapeutic strategies. This compound is a prime example of how synthetic complexity can yield significant scientific innovation.

Synonyms
CT 3570
Phenyl 3-(piperidinomethyl)-1,4-benzodioxan-6-yl ketone hydrochloride
Chlorhydrate de piperidinomethyl-2 benzoyl-7 benzodioxanne-1,4 [French]
KETONE, PHENYL 3-(PIPERIDINOMETHYL)-1,4-BENZODIOXAN-6-YL, HYDROCHLORIDE
3818-98-2
Chlorhydrate de piperidinomethyl-2 benzoyl-7 benzodioxanne-1,4