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Phenyl 4-amino-2-hydroxybenzoate

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Identification
Molecular formula
C13H11NO3
CAS number
134-61-6
IUPAC name
phenyl 4-amino-2-hydroxy-benzoate
State
State

At room temperature, Phenyl 4-amino-2-hydroxybenzoate is typically found in a solid state.

Melting point (Celsius)
190.00
Melting point (Kelvin)
463.15
Boiling point (Celsius)
315.50
Boiling point (Kelvin)
588.65
General information
Molecular weight
229.23g/mol
Molar mass
229.2310g/mol
Density
1.3000g/cm3
Appearence

Phenyl 4-amino-2-hydroxybenzoate typically appears as a crystalline solid. It can be colorless or have a slight yellow tinge, depending on purity and specific conditions.

Comment on solubility

Solubility of Phenyl 4-Amino-2-Hydroxybenzoate

The solubility of phenyl 4-amino-2-hydroxybenzoate, often referred to as a salicylate derivative, can be influenced by several factors. Understanding these can provide insights into potential applications and behaviors of this compound in various solvents.

Factors Affecting Solubility

  • Polarity: The compound contains both polar and non-polar functional groups, which can affect its solubility in different solvents. Generally, phenyl 4-amino-2-hydroxybenzoate is more soluble in polar solvents such as water and alcohols than in non-polar solvents.
  • pH Levels: The solubility might vary significantly depending on the pH of the solution. For instance, in acidic conditions, the amino group can participate in protonation, potentially enhancing solubility.
  • Temperature: Increasing the temperature typically increases solubility as kinetic energy overcomes intermolecular forces.

To summarize, while phenyl 4-amino-2-hydroxybenzoate shows a tendency to dissolve in more polar environments, its solubility is also **highly dependent** on pH and temperature conditions. This complex interplay contributes to its utility in different chemical applications.

Interesting facts

Interesting Facts about Phenyl 4-Amino-2-Hydroxybenzoate

Phenyl 4-amino-2-hydroxybenzoate, commonly known as a derivative of salicylic acid, exhibits remarkable properties that make it fascinating for both scientific inquiry and practical applications. This compound belongs to the class of compounds known as esters and is often used in diverse fields, particularly in pharmaceuticals and cosmetics.

Key Characteristics

  • Biological Activity: Phenyl 4-amino-2-hydroxybenzoate is notable for its anti-inflammatory and analgesic properties, which make it an important component in various medicinal formulations.
  • Role as a Sunscreen Agent: This compound can also be utilized as a filter to absorb UV radiation, protecting the skin from harmful sun exposure.
  • Antimicrobial Effects: Research has indicated that it may possess antimicrobial activity, making it a candidate for inclusion in topical treatments and ointments.

Applications in Modern Science

The applications of phenyl 4-amino-2-hydroxybenzoate are expanding, with its role as a sunscreen agent during the summer months gaining particular attention. It serves:

  • As an essential ingredient in personal care products like lotions and creams.
  • In the pharmaceutical industry for the formulation of topical medications.
  • As a potential candidate in drug development due to its biological properties.

Quote on the Importance of Research

As scientists continuously explore the possibilities of organic compounds, they remind us that "the rearrangement of atoms can lead to a plethora of solutions in health and wellness." This statement underscores the significance of understanding compounds like phenyl 4-amino-2-hydroxybenzoate.

In conclusion, the diverse applications and remarkable properties of phenyl 4-amino-2-hydroxybenzoate make it an intriguing subject of study, highlighting the vital intersection between chemistry and real-world applications.

Synonyms
Phenyl 4-aminosalicylate
133-11-9
PHENYL AMINOSALICYLATE
Fenamisal
phenyl 4-amino-2-hydroxybenzoate
Tebamin
Phenyl PAS
Tebanyl
p-Aminosalol
Pheny-PAS-Tebamin
Phenyl-4-aminosalicylate
Tebamyn
Tebamin-Leo
Phenyl-PAS-Tebamin
Phenyl p-aminosalicylate
Fenamisalum
FR 7
Benzoic acid, 4-amino-2-hydroxy-, phenyl ester
p-Aminosalicylic acid, phenyl ester
Fenamisalum [INN-Latin]
EINECS 205-092-8
Fenamisal [INN]
NSC 40144
NSC-40144
UNII-52936SIP7V
Phenyl aminosalicylate [USAN]
Salicylic acid, 4-amino-, phenyl ester
Salicyclic acid, 4-amino-, phenyl ester
52936SIP7V
NSC40144
DTXSID7021994
Fenamisal (INN)
MFCD00007788
Fenamisal; NSC 40144; PAS-Tebamin
NCGC00095933-01
Fenamisalum (INN-Latin)
FENAMISAL (MART.)
FENAMISAL [MART.]
Phenyl aminosalicylate (USAN)
DTXCID201994
Phenyl4-aminosalicylate
CAS-133-11-9
SR-01000363421
4-amino-2-hydroxybenzoic acid phenyl ester
PAS-Tebamin
phenyl 4-amino-2-hydroxy-benzoate
phenyl-aminosalicylate
Spectrum_001329
SpecPlus_000892
Spectrum2_000439
Spectrum3_000877
Spectrum4_000717
Spectrum5_001125
Pheny-Pas-Tebamin (TN)
FENAMISAL [WHO-DD]
Oprea1_625699
BSPBio_002553
KBioGR_001273
KBioSS_001809
SPECTRUM305025
Salicyclic acid, phenyl ester
DivK1c_006988
SCHEMBL194250
SPBio_000458
CHEMBL1200868
KBio1_001932
KBio2_001809
KBio2_004377
KBio2_006945
KBio3_002053
CHEBI:114203
HMS2091C03
Pharmakon1600-00305025
PHENYL AMINOSALICYLATE [MI]
Tox21_111538
CCG-39964
NSC755837
para-aminosalicylic acid phenyl ester
STL477797
AKOS015963404
Tox21_111538_1
DB06807
NSC-755837
SB80012
NCGC00095933-02
NCGC00095933-04
AC-19340
AS-66998
SY287601
SBI-0052877.P003
DB-005471
PHENYL AMINOSALICYLATE [ORANGE BOOK]
NS00024266
D05460
F19835
AB00053247_02
EN300-18532289
SR-01000363421-1
SR-01000363421-2
BRD-K73157543-001-02-5
BRD-K73157543-001-03-3
BRD-K73157543-001-04-1
Q27195393
205-092-8