Interesting facts
Interesting Facts about Phosphonoformic Acid
Phosphonoformic acid, also known as bisphosphonic acid, is a fascinating compound that has gained significance in various fields, particularly in biochemistry and medicine. Here are some engaging insights:
- Structure and Function: Phosphonoformic acid contains a phosphorus atom, bonded to an acidic group and two hydroxymethyl groups. This unique structure allows it to interact with biological systems in meaningful ways.
- Biological Importance: It is recognized for its ability to inhibit the enzyme that plays a crucial role in nucleic acid metabolism. This property makes phosphonoformic acid a potential candidate for antiviral therapies, specifically against viruses such as HIV and cytomegalovirus.
- Research Applications: In addition to its antiviral properties, the compound is studied for its application in cancer research. It may help in uncovering new pathways and treatments for various types of cancer.
- Environmental Impact: Phosphonoformic acid’s role extends to environmental science as well. It is being investigated for its potential in bioremediation strategies, where it could help in breaking down hazardous substances.
Quotes from prominent researchers highlight the compound's versatility: "The applications of phosphonoformic acid in medicinal chemistry are both vast and promising, paving the way for breakthrough therapies."
Understanding phosphonoformic acid is not just an exploration of its chemical properties, but an exciting journey into its role as a tool in tackling some of humanity's most pressing health challenges.
Synonyms
foscarnet
Phosphonoformic acid
Phosphonoformate
Carboxyphosphonic acid
4428-95-9
Foscarmet
Foscavir
phosphonocarboxylic acid
phosphonomethanoic acid
Dihydroxyphosphinecarboxylic acid oxide
Formic acid, phosphono-
UNII-364P9RVW4X
364P9RVW4X
HSDB 8122
CHEBI:127780
Phosphinecarboxylic acid, dihydroxy-, oxide
dihydroxyphosphanecarboxylic acid oxide
CHEMBL666
DTXSID0048478
J05AD01
Phgosphonocarboxylic acid
NSC313410
Forscarnet
1nki
Foscarnet (PFA)
Spectrum_001359
PFA & rIFN.alpha.A
Spectrum2_000668
Spectrum3_001484
Spectrum4_000840
Spectrum5_000932
FOSCARNET [VANDF]
phosphonoformic acid(PFA)
MSL & PFA
FOSCARNET [WHO-DD]
Phosphono-formic acid(PFA)
hydroxycarbonylphosphonic acid
SCHEMBL23633
BSPBio_003067
Foscarnet & IFN-.ALPHA.
KBioGR_001419
KBioSS_001839
DivK1c_000915
SPBio_000735
GTPL5497
DTXCID0028452
KBio1_000915
KBio2_001839
KBio2_004407
KBio2_006975
KBio3_002567
NINDS_000915
ZJAOAACCNHFJAH-UHFFFAOYSA-N
BDBM50011181
Phosphonoformic acid & IFN-.ALPHA.
AKOS006281397
DB00529
IDI1_000915
(PFA)dihydroxyphosphinecarboxylic acid oxide
dihydroxyphosphinecarboxylic acid oxide(PFA)
NS00005428
C06456
EN300-708767
Q420387
BRD-K85146014-314-05-4
BRD-K85146014-314-06-2
BRD-K85146014-314-07-0
Phosphonoformate(trisodium) & Recombinant Alpha-A Interferon
Dihydroxyphosphinecarboxylic acid oxide and MSL, neutralizing monoclonal antibody
Solubility of Phosphonoformic Acid
Phosphonoformic acid, with the chemical formula C(H3O4P), is notably soluble in water, exhibiting a strong affinity for this polar solvent. This property can be attributed to its molecular structure that comprises both hydrophilic (water-attracting) and hydrophobic (water-repelling) regions.
Key Aspects of Solubility:
In summary, phosphonoformic acid's solubility characteristics reflect its unique interactions with water, which can be optimally leveraged in various chemical and biological applications. As one source aptly puts it, "the greater the interaction with water, the more effective the application in aqueous solutions." This emphasizes the critical role solubility plays in utilizing this compound effectively.