Interesting facts
Interesting Facts about Piperazine
Piperazine is a fascinating compound that plays a significant role in both industrial applications and medicinal chemistry. As a cyclic chemical structure, it consists of a six-membered ring containing two nitrogen atoms in adjacent positions. Here are some intriguing aspects of piperazine:
- Pharmaceutical Applications: Piperazine is widely utilized in the pharmaceutical industry as a precursor for various medications. It is particularly well-known for its role in the synthesis of anti-anxiety drugs and anti-depressants.
- Anti-parasitic Properties: Piperazine compounds are effective against certain parasitic infections and are used in veterinary medicine as well. They help in treating conditions caused by worms in both animals and humans.
- Versatile Building Block: The piperazine structure serves as a valuable building block in organic synthesis, leading to the development of a diverse range of derivatives with varying biological activities.
- Analytical Chemistry: Piperazine and its derivatives can be utilized in the field of analytical chemistry, particularly in chromatography, where they are instrumental in separating and identifying complex mixtures.
Researchers and chemists find piperazine particularly interesting due to its ability to form various derivatives, which can enhance or alter its pharmacological properties. As noted by chemists, “The versatility of piperazine in medicinal chemistry makes it an essential scaffold in drug discovery.”
In addition to its practical applications, piperazine's distinctive structure and reactivity continue to be subjects of extensive study, providing a rich area of exploration for both students and professionals in the field of chemistry.
Synonyms
piperazine
110-85-0
Diethylenediamine
1,4-Diazacyclohexane
Piperazin
Hexahydropyrazine
Piperazidine
Antiren
1,4-Piperazine
Diethyleneimine
Pipersol
Eraverm
Dispermine
Lumbrical
Wurmirazin
Uvilon
Piperazine, anhydrous
Vermex
Worm-A-Ton
1,4-Diethylenediamine
Asca-Trol No. 3
Pyrazine hexahydride
Hexahydro-1,4-diazine
Pyrazine, hexahydro-
Piperazine anhydrous
Piperazine (USP)
Vermizine (TN)
NSC 474
MFCD00005953
CCRIS 5950
HSDB 1093
UNII-1RTM4PAL0V
1RTM4PAL0V
EINECS 203-808-3
Piperazine [USP]
BRN 0102555
PIPERAZINUM
1,4 Diazacyclohexane
DTXSID1021164
CHEBI:28568
NSC-474
DTXCID701164
NSC474
FEMA NO. 4250
EC 203-808-3
5-23-01-00030 (Beilstein Handbook Reference)
Eraverm (VAN)
Piperazin [German]
NCGC00094762-03
Vermizine
PIPERAZINE (II)
PIPERAZINE [II]
Upixon
PIPERAZINE (MART.)
PIPERAZINE [MART.]
PIPERAZINE (USP-RS)
PIPERAZINE [USP-RS]
Anhydrous piperazine
Piperazin [Germany]
Piperazina
PIPERAZINE (USP MONOGRAPH)
PIPERAZINE [USP MONOGRAPH]
1,4 Piperazine
CAS-110-85-0
PZE
UN2579
piperizine
piperzine
piprazine
exahydropyrazine
Piperazine-
Hexahydropirazine
7-piperazine
4-diazacyclohexane
Piperazine,anhydrous
Piperazine, 99%
Tasnon (Salt/Mix)
Exelmin (Salt/Mix)
Vermidol (Salt/Mix)
Piperazine - anhydrous
Vermizine (Salt/Mix)
Spectrum_001113
PIPERAZINE [MI]
Spectrum5_001817
PIPERAZINE [FHFI]
PIPERAZINE [HSDB]
PIPERAZINE (anhydrous)
WLN: T6M DMTJ
PIPERAZINE [VANDF]
PIPERAZINUM [HPUS]
Piperazine, p.a., 98%
CHEMBL1412
NCIOpen2_000984
NCIOpen2_000988
NCIOpen2_001024
NCIOpen2_001031
NCIOpen2_001033
NCIOpen2_001071
NCIOpen2_001073
NCIOpen2_001111
NCIOpen2_001151
NCIOpen2_001231
NCIOpen2_001262
NCIOpen2_001269
NCIOpen2_004830
NCIOpen2_004834
NCIOpen2_004862
NCIOpen2_004874
NCIOpen2_004904
NCIOpen2_004910
NCIOpen2_004914
NCIOpen2_004942
NCIOpen2_004952
NCIOpen2_004954
NCIOpen2_004982
NCIOpen2_004992
NCIOpen2_004994
NCIOpen2_005022
NCIOpen2_005032
NCIOpen2_005034
NCIOpen2_005062
NCIOpen2_005072
NCIOpen2_005102
NCIOpen2_005108
NCIOpen2_005145
NCIOpen2_005182
NCIOpen2_005185
NCIOpen2_005187
NCIOpen2_005200
NCIOpen2_005575
NCIOpen2_005980
NCIOpen2_009422
PIPERAZINE [WHO-DD]
KBioSS_001593
BIDD:GT0273
DivK1c_000038
SPECTRUM1500490
Piperazine, analytical standard
PIPERAZINE [GREEN BOOK]
HMS500B20
KBio1_000038
KBio2_001593
KBio2_004161
KBio2_006729
P02CB01
NINDS_000038
HMS1920H20
HMS2092A03
HMS3885L08
Pharmakon1600-01500490
BCP24060
HY-B0912
Piperazine, ReagentPlus(R), 99%
STR00051
Tox21_113564
Tox21_202242
Tox21_300104
NSC757283
s4574
STL169348
Piperazine [UN2579] [Corrosive]
AKOS000269028
CCG-212753
CS-4381
DB00592
FP31694
LF-0561
NSC-757283
UN 2579
IDI1_000038
NCGC00094762-01
NCGC00094762-02
NCGC00094762-04
NCGC00094762-05
NCGC00094762-08
NCGC00254077-01
NCGC00259791-01
Piperazine, anhydrous, >=99.0% (T)
BP-31252
Roundworm De-Wormer For Cats and Kittens
SBI-0051485.P003
NS00008207
P0446
P0447
EN300-33920
C07973
D00807
AB00052073_03
Piperazine, BioUltra, anhydrous, >=99.0% (T)
Q409292
SR-05000001700
SR-05000001700-1
BRD-K13249881-001-02-3
F0001-0226
Z1245537944
InChI=1/C4H10N2/c1-2-6-4-3-5-1/h5-6H,1-4H
Piperazine, United States Pharmacopeia (USP) Reference Standard
TRIMETAZIDINE DIHYDROCHLORIDE IMPURITY G [EP IMPURITY]
203-808-3
31977-51-2
Solubility of Piperazine (C4H10N2)
Piperazine, with the chemical formula C4H10N2, exhibits interesting solubility properties that make it a versatile compound in various applications. Here are some key points regarding its solubility:
In summary, piperazine's ability to dissolve readily in both polar solvents like water and various organic solvents highlights its importance in both industrial and medicinal chemistry. As one of the cornerstones in the study of heterocyclic compounds, understanding its solubility can influence its practical applications and effectiveness.