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Piperazine-2,4,5-trichlorophenol

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Identification
Molecular formula
C10H11Cl3NO
CAS number
89-38-3
IUPAC name
piperazine;2,4,5-trichlorophenol
State
State

At room temperature, Piperazine-2,4,5-trichlorophenol is generally found in a solid state. It is stable under normal conditions but should be handled carefully in a laboratory setting.

Melting point (Celsius)
69.00
Melting point (Kelvin)
342.15
Boiling point (Celsius)
311.00
Boiling point (Kelvin)
584.15
General information
Molecular weight
319.02g/mol
Molar mass
319.0200g/mol
Density
1.7000g/cm3
Appearence

Piperazine-2,4,5-trichlorophenol typically appears as a crystalline solid. The compound can vary in color from pale yellow to white, depending on purity and specific conditions of crystallization.

Comment on solubility

Solubility of Piperazine; 2,4,5-Trichlorophenol

The solubility characteristics of piperazine and 2,4,5-trichlorophenol are quite intriguing due to their distinct chemical nature.

Piperazine

Piperazine is known for its high solubility in water and many organic solvents. This is primarily because of its ability to form hydrogen bonds due to the presence of nitrogen atoms in its structure. Here are some key points regarding its solubility:

  • Highly soluble in water: Piperazine readily dissolves in water due to its polar nature.
  • Miscibility with organic solvents: It is also miscible with several organic solvents, enhancing its utility in various chemical processes.
  • Temperature dependence: The solubility of piperazine may increase with temperature, which is typical for many organic compounds.

2,4,5-Trichlorophenol

In contrast, the solubility of 2,4,5-trichlorophenol is influenced by its aromatic nature and the presence of chlorine atoms, which affect the overall polarity:

  • Low water solubility: This compound exhibits limited solubility in water, reflecting its hydrophobic characteristics enhanced by chlorination.
  • Solubility in organic solvents: It tends to dissolve better in organic solvents such as alcohols and ethers due to the nonpolar nature of its aromatic structure.
  • Environmental considerations: Its low solubility in water is significant in environmental chemistry, impacting its behavior and bioavailability in aquatic systems.

In summary, while piperazine demonstrates an impressive solubility in both polar and nonpolar solvents, 2,4,5-trichlorophenol showcases limited water solubility with a propensity for organic solvents. Understanding these solubility characteristics is crucial for applications in pharmaceuticals, environmental science, and chemical synthesis.

Interesting facts

Interesting Facts about Piperazine; 2,4,5-Trichlorophenol

Piperazine, a heterocyclic organic compound, and 2,4,5-trichlorophenol, a chlorinated phenol, both play significant roles in various fields of science and industry. Here are some intriguing insights into this unique combination of compounds:

  • Piperazine is primarily used as a therapeutic agent. It is often found in treatments for conditions such as depression and anxiety. Research has shown that this compound has potential in enhancing neuroactive properties.
  • 2,4,5-Trichlorophenol, on the other hand, has been widely used as a disinfectant and in the production of pesticides. It is notable for its effectiveness in controlling bacterial growth, making it essential in various industrial applications.
  • The interaction between these two compounds can lead to research opportunities in the development of new pharmaceuticals or pesticide formulations, showcasing their versatility.
  • Both compounds feature unique structural characteristics; piperazine with its cyclic structure and 2,4,5-trichlorophenol with multiple chlorine substituents that enhance its reactivity.
  • Historically, piperazine was first identified in the early 19th century, while chlorophenols like 2,4,5-trichlorophenol emerged in the mid-20th century, reflecting advancements in organic synthesis techniques.

Quote: "The convergence of the pharmaceutical and agricultural sectors illustrates the interconnectedness of chemistry in addressing real-world challenges."

Understanding these compounds not only highlights their individual properties but also their potential synergies when combined. The careful study and application of piperazine and 2,4,5-trichlorophenol could lead to innovative solutions in both health and environmental fields.

Synonyms
TRICLOFENOL PIPERAZINE
Ranestol
Triclofenol piperazate
CI-416
Trichlorophenol piperazine
CN-5834-5931B
IN 29-5931B
Triclofenol piperazina
Bis(2,4,5-trichlorophenol)piperazine
Piperazine di(2,4,5-trichlorophenoxide)
444YK71BIV
IN 29-5931
Piperazine salt of bis(2,4,5-trichlorophenol)
NSC-77747
Piperazine compound (1:2) with 2,4,5-trichlorophenol
IN-29-5931B
piperazine; 2,4,5-trichlorophenol
Ranestol (TN)
NSC 77747
Triclofenol piperazina [INN-Spanish]
Triclofenolum piperazinum [INN-Latin]
IN29-5931B
Triclofenol piperazine [USAN:INN:BAN]
Piperazine bis(2,4,5-trichlorophenolate)
Triclofenolum piperazinum
UNII-444YK71BIV
SCHEMBL636779
Piperazine compound with 2,4,5-trichlorophenol (1:2)
CHEMBL2107709
TRICLOFENOL PIPERAZINE [MI]
Triclofenol piperazine (USAN/INN)
TRICLOFENOL PIPERAZINE [INN]
TRICLOFENOL PIPERAZINE [USAN]
AKOS040754252
CN-5834-5931 B
CN-5834-5931-B
Piperazine bis(2,4, 5-trichlorophenolate)
D06224
Q27258703
2,4,5-Trichlorophenol compound with piperazine (1:1)
Piperazine compound (1:2) with 2,4, 5-trichlorophenol