Skip to main content

Piperazine dihydrochloride

ADVERTISEMENT
Identification
Molecular formula
C4H12N2Cl2
CAS number
142-64-3
IUPAC name
piperazine;dihydrochloride
State
State

At room temperature, piperazine dihydrochloride exists as a solid. It is typically provided in a powder or crystalline form, making it easy to handle and measure for various applications.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
305.00
Boiling point (Kelvin)
578.15
General information
Molecular weight
190.10g/mol
Molar mass
190.0980g/mol
Density
1.0970g/cm3
Appearence

Piperazine dihydrochloride appears as a white crystalline powder. It is hygroscopic and can form clumps if exposed to moisture for extended periods.

Comment on solubility

Solubility of Piperazine Dihydrochloride

Piperazine dihydrochloride, with the chemical formula C4H10N2·2HCl, exhibits notable solubility characteristics that are essential for its application in various fields. Its solubility can be summarized as follows:

  • Water Solubility: Piperazine dihydrochloride is highly soluble in water, which makes it quite effective in pharmaceutical formulations.
  • Solvents: This compound is also soluble in other polar solvents due to its ionic nature, enabling it to dissolve in ethanol and methanol to varying extents.
  • Temperature Dependency: Like many salts, the solubility of piperazine dihydrochloride in water typically increases with rising temperature, enhancing its dissolution rate.
  • pH Influence: The solubility can be influenced by the pH of the solution, with acidic conditions potentially affecting its ionization state and solubility dynamics.

In conclusion, the solubility traits of piperazine dihydrochloride make it a versatile compound in medicinal chemistry, allowing it to be effectively utilized in a variety of aqueous environments. The statement, "The solubility of a compound defines its reactivity and applicability," holds particularly true for this substance.

Interesting facts

Interesting Facts about Piperazine Dihydrochloride

Piperazine dihydrochloride is a fascinating compound with a variety of applications, both clinically and industrially. Known for its distinct chemical structure, piperazine plays a significant role in medicinal chemistry.

Key Applications

  • Pharmaceutical Use: Piperazine dihydrochloride is primarily utilized in the synthesis of various pharmaceuticals, particularly as an anti-helminthic agent to combat parasitic infections.
  • Antidepressant Properties: This compound has been explored for its potential antidepressant effects, highlighting its importance in the study of mental health treatments.
  • Industrial Applications: Beyond medicine, piperazine dihydrochloride finds use in the production of polymers and surfactants, demonstrating its versatility across different fields.

Chemical Characteristics

The unique structure of piperazine—consisting of a six-membered ring containing two nitrogen atoms—imparts specific properties that enhance its functionality:

  • Stability: The presence of nitrogen contributes to the compound's stability under various conditions.
  • Solubility: This compound is generally soluble in water due to its ionic nature, making it easier to administer in various formulations.

Research Insights

Scientists have continually researched piperazine dihydrochloride to identify its potential beyond traditional uses. Recent studies suggest:

  • Neurotransmitter Modulation: It may have effects on neurotransmitter systems, particularly serotonin and dopamine, which is crucial for understanding its psychotropic properties.
  • Potential in Cancer Therapy: Emerging research is investigating its role in cancer treatment due to interactions with certain receptors.

Quote on Innovation

As one researcher eloquently put it: "The study of piperazine derivatives opens doors to a myriad of therapeutic possibilities that could redefine patient care."

Overall, piperazine dihydrochloride stands out as a noteworthy compound, bridging the gap between basic chemistry and practical applications in health and industry. Its ongoing research promises to unveil even more insights into its capabilities!

Synonyms
Piperazine dihydrochloride
142-64-3
Dowzene DHC
Piperazine, dihydrochloride
Piperazine wormer premix
Caswell No. 668
piperazine;dihydrochloride
Diethylenediamine dihydrochloride
HSDB 1182
Ascarex D
EINECS 205-551-2
EPA Pesticide Chemical Code 067401
UNII-17VU4Z4W88
DTXSID4047096
Piperazinium dichloride
17VU4Z4W88
DTXCID2027096
Piperazine dihydrochloride [USP]
Dihydro Pip Wormer
Piperazine,hydrochloride(1:2)
Piperazine dihydrochloride (USP)
PIPERAZINE DIHYDROCHLORIDE (MART.)
PIPERAZINE DIHYDROCHLORIDE [MART.]
PIPERAZINE DIHYDROCHLORIDE (USP-RS)
PIPERAZINE DIHYDROCHLORIDE [USP-RS]
PIPERAZINE DIHYDROCHLORIDE (USP MONOGRAPH)
PIPERAZINE DIHYDROCHLORIDE [USP MONOGRAPH]
Dihydrochloride salt of diethylenediamine
SCHEMBL282455
piperazine-1,4-diium chloride
CHEMBL3188015
Piperazine, hydrochloride (1:2)
PIPERAZIDINE DIHYDROCHLORIDE
Tox21_302343
AKOS022183484
GS-5897
HEXAHYDROPYRAZINE DIHYDROCHLORIDE
PIPERAZINE HYDROCHLORIDE [HSDB]
NCGC00256286-01
PIPERAZINE HYDROCHLORIDE [WHO-DD]
CAS-142-64-3
DB-042639
CS-0155212
NS00079242
P0450
P2491
PIPERAZINE HYDROCHLORIDE [GREEN BOOK]
E75922
PIPERAZINE DIHYDROCHLORIDE [GREEN BOOK]
Q20966050
205-551-2