Interesting facts
Interesting Facts about Piperidine
Piperidine is an intriguing organic compound that belongs to the class of saturated heterocycles. This six-membered ring structure features one nitrogen atom and five carbon atoms, making it a fundamental building block in organic chemistry.
Structural Characteristics
- Basis of Many Reactions: The nitrogen atom in piperidine offers basic properties, making it a good nucleophile. This allows piperidine to participate in numerous chemical reactions.
- Substituted Variants: It has numerous substituted derivatives, which are often used as intermediates in the synthesis of pharmaceuticals.
Applications
- Pharmaceutical Industry: Piperidine derivatives are prevalent in medicinal chemistry and drug development, enabling the creation of various therapeutic agents.
- Agricultural Chemicals: It's also utilized in the synthesis of agrochemicals, demonstrating its versatility beyond pharmaceuticals.
- Research Tool: It serves as a reagent in organic synthesis, particularly in the formation of C–N bonds.
Interesting Features
In addition to its chemical applications, piperidine's unique profile includes:
- Psychoactive Properties: Piperidine can be formed during the metabolism of certain drugs, showcasing its relevance in pharmacology.
- The "Piperidine Ring": Its structure is often referred to in discussions about heterocycles, highlighting its significance in organic chemistry education.
As a result, piperidine acts as both a versatile chemical building block and an essential compound within various scientific disciplines, making it a fascinating subject of study in the field of chemistry.
Synonyms
PIPERIDINE
110-89-4
Hexahydropyridine
Cyclopentimine
Azacyclohexane
Piperidin
Cypentil
Hexazane
Pentamethyleneimine
Pentamethylenimine
Perhydropyridine
Pyridine, hexahydro-
Pentamethyleneamine
azinane
FEMA No. 2908
CCRIS 967
piperdine
HSDB 114
EINECS 203-813-0
DTXSID6021165
UNII-67I85E138Y
CHEBI:18049
AI3-24114
Piperidine, homopolymer
MFCD00005979
67I85E138Y
CHEMBL15487
DTXCID101165
PIP
EC 203-813-0
Piperidin [German]
89014-30-2
Piperidine, puriss. p.a., >=99.0% (GC/T)
UN2401
piperadine
pyperidine
N-piperidine
Piperidine [UN2401] [Corrosive]
Piperidine, 99%
PENTAMETHSENEIMINE
Hexazane; Azacyclohexane
PIPERIDINE [MI]
PIPERIDINE [FCC]
PIPERIDINE [FHFI]
PIPERIDINE [HSDB]
TOLPERISONE_met028
Piperidine on Rasta Resin
NCIMech_000312
Piperidine (Peptide Grade)
NCIOpen2_007828
PIPERIDINE [WHO-DD]
Piperidine, >=99%, FG
Piperidine, >=99%, FCC
Piperidine, analytical standard
GTPL5477
FEMA 2908
Piperidine (Peptide Grade), 99%
Piperidine, ReagentPlus(R), 99%
STR00031
Tox21_201175
BDBM50026449
Piperidine [UN2401] [Corrosive]
AKOS002309795
UN 2401
Piperidine, biotech. grade, >=99.5%
NCGC00248946-01
NCGC00258727-01
CAS-110-89-4
Piperidine, purum, >=96.0% (GC/T)
Piperidine, SAJ first grade, >=99.0%
DB-188863
NS00009032
P0453
Piperidine, puriss. plus, >=99.5% (GC)
C01746
P-6865
Piperidine, >=99.5%, purified by redistillation
Q410234
InChI=1/C5H11N/c1-2-4-6-5-3-1/h6H,1-5H
203-813-0
52167-54-1
StratoSpheres(TM) PL-PIP (Piperidine) resin, 50-100 mesh, extent of labeling: 3.0-4.0 mmol/g loading, 1 % cross-linked
Solubility of Piperidine
Piperidine, a six-membered heterocyclic amine with the chemical formula C5H11N, exhibits interesting solubility properties that are noteworthy for its applications in organic synthesis and pharmaceuticals.
In terms of solubility:
Overall, the high solubility of piperidine in both water and organic solvents underscores its utility in various chemical synthesis processes, and its ability to act as a solvent for other polar or ionic compounds. The interaction of piperidine with these solvents can be leveraged to influence the course of reactions, showcasing the importance of solubility in chemical research.