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Piperidine-4-carboxamide

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Identification
Molecular formula
C6H12N2O
CAS number
7200-56-6
IUPAC name
piperidine-4-carboxamide
State
State

Piperidine-4-carboxamide is typically a solid at room temperature. It is stable under ordinary conditions and does not readily volatilize.

Melting point (Celsius)
89.50
Melting point (Kelvin)
362.65
Boiling point (Celsius)
326.20
Boiling point (Kelvin)
599.35
General information
Molecular weight
128.17g/mol
Molar mass
128.1730g/mol
Density
1.1090g/cm3
Appearence

Piperidine-4-carboxamide appears as a white crystalline powder. It may also appear as white to off-white solid depending on the purity and specific form.

Comment on solubility

Solubility of Piperidine-4-carboxamide (C6H12N2O)

Piperidine-4-carboxamide is known for its interesting solubility characteristics, which can greatly influence its practical applications in various fields, particularly in medicinal chemistry.

Solubility Profile

This compound exhibits the following solubility properties:

  • Soluble in water: Piperidine-4-carboxamide readily dissolves in water due to its ability to form hydrogen bonds, making it amenable for use in aqueous solutions.
  • Soluble in organic solvents: It is also soluble in a variety of organic solvents such as ethanol and methanol, expanding its utility in organic reactions.
  • Temperature effects: Solubility may vary with temperature; typically, increased temperatures enhance its solubility in both water and organic solvents.

As with many organic compounds, solubility in specific solvents can lead to unique reactivity patterns and influence the efficacy of piperidine-4-carboxamide as a precursor in synthetic pathways. Understanding these solubility properties is essential for optimizing formulations and enhancing the bioavailability of associated drugs.

Conclusion

In conclusion, the solubility of piperidine-4-carboxamide not only reflects its chemical nature but also points to its potential in diverse applications. The ability to dissolve in both polar and non-polar environments is a critical factor to consider when utilizing this compound in research and industry.

Interesting facts

Interesting Facts about Piperidine-4-carboxamide

Piperidine-4-carboxamide is a fascinating compound that belongs to the class of cyclic amines. Here are a few intriguing points that highlight its significance in various fields:

  • Structural Characteristics: Piperidine-4-carboxamide features a six-membered ring containing a nitrogen atom, which makes it a key player in organic synthesis and medicinal chemistry.
  • Biological Importance: This compound has garnered attention in pharmaceutical research due to its potential in developing therapeutic agents, particularly those targeting neurological disorders.
  • Synthetic Utility: Its functional groups allow for various chemical reactions, making it a versatile intermediate in the synthesis of more complex molecules.
  • Research Applications: Piperidine derivatives are widely studied for their influence on receptor activity, which is critical in drug development and understanding biochemical pathways.
  • Toxicity and Safety: Like many nitrogen-containing compounds, the safety profile of piperidine-4-carboxamide needs careful evaluation, as its derivatives can exhibit varying levels of toxicity.

In the words of a researcher, "The potential for piperidine-4-carboxamide in creating compounds that effectively interact with biological systems opens new avenues in drug discovery."
Researchers continue to explore its applications and implications within biochemistry and pharmacology, emphasizing the ongoing evolution of this remarkable compound.

Synonyms
Piperidine-4-carboxamide
Isonipecotamide
39546-32-2
4-Piperidinecarboxamide
Hexahydroisonicotinamide
4-carbamoylpiperidine
4-piperidine carboxamide
4-piperidine-d9-carboxamide
MFCD00038012
CZE2810T4X
4-carboxamidopiperidine
Piperidine-4-carboxylic acid amide
EINECS 254-501-6
NSC 82318
NSC-82318
4-(aminocarbonyl)piperidine
4-PIPERIDYLCARBOXAMIDE
1219803-20-9
DTXSID7068182
iso-nipecotamide
NSC82318
Isonipecotic acid amide
4-piperidine-carboxamide
4-aminocarbonylpiperidine
SCHEMBL1298
UNII-CZE2810T4X
Piperidin-4-carboxylic amide
4-Piperidinecarboxamide, 97%
DTXCID0039643
SCHEMBL12461666
CHEBI:166563
ALBB-025738
BCP18799
STR01101
AC-539
STL183252
AKOS000119354
CS-W013464
FH34632
PB25917
BP-11768
SY005311
TS-01685
DB-013239
I0255
NS00000553
EN300-20201
Q63392690
F2190-0334
V5Y