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Piperidine-4-sulfonic acid

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Identification
Molecular formula
C5H11NO3S
CAS number
6962-54-3
IUPAC name
piperidine-4-sulfonic acid
State
State

At room temperature, Piperidine-4-sulfonic acid is in a solid state. Being a crystalline powder, it is stable under normal conditions of use and storage, assuming it is kept dry and away from excessive heat or light.

Melting point (Celsius)
284.00
Melting point (Kelvin)
557.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
181.23g/mol
Molar mass
181.2290g/mol
Density
1.5800g/cm3
Appearence

Piperidine-4-sulfonic acid typically appears as a white crystalline solid. The compound is often supplied in its hydrated form and is hygroscopic, meaning it can absorb moisture from the air, which may affect its appearance over time if not stored properly.

Comment on solubility

Solubility of Piperidine-4-sulfonic Acid

Piperidine-4-sulfonic acid, with the chemical formula C5H11NO3S, is known for its solubility characteristics that are crucial in both industrial applications and laboratory settings. Here are some key observations regarding its solubility:

  • Highly Soluble in Water: Piperidine-4-sulfonic acid is typically very soluble in water, making it an excellent choice for aqueous reactions and processes.
  • Polar Nature: The presence of the sulfonic acid group (-SO3H) contributes to its polarity, enhancing its ability to interact with water molecules.
  • Influence of pH: The solubility may vary with pH, as the protonation state of the sulfonic acid group can affect its overall stability and solvation.
  • Limited Solubility in Nonpolar Solvents: Like many sulfonic acids, piperidine-4-sulfonic acid exhibits low solubility in nonpolar organic solvents, which is a common trait among polar compounds.

In summary, the solubility of piperidine-4-sulfonic acid in water, coupled with its polar characteristics, underlines its functionality in various chemical applications. This aspect of its properties is essential for researchers looking to utilize it effectively in syntheses and formulations.

Interesting facts

Interesting Facts about Piperidine-4-Sulfonic Acid

Piperidine-4-sulfonic acid is a fascinating compound in the realm of organic chemistry and biochemistry. Here are some key facts that highlight its significance:

  • Structural Influence: The presence of both a piperidine ring and a sulfonic acid group makes this compound uniquely reactive. It can act as a nucleophile in various chemical reactions, enabling transformations that are critical in organic synthesis.
  • Biological Role: Piperidine derivatives, including piperidine-4-sulfonic acid, play a vital role in biological systems. They can act as intermediates in the synthesis of pharmaceuticals, contributing to medicinal chemistry.
  • pH Regulation: Due to its sulfonic acid group, piperidine-4-sulfonic acid is often utilized in buffer solutions. It helps maintain a stable pH in various chemical and biological experiments, which is crucial for accurate results.
  • Applications in Research: This compound is widely used in the field of neuroscience. It has been studied for its role in the activity of certain neurotransmitter systems, making it a subject of interest for researchers investigating brain function and pharmacology.
  • Synthetic Utility: Due to its ability to form sulfonamides, piperidine-4-sulfonic acid can be used in the synthesis of various bioactive molecules, broadening the scope of synthetic organic chemistry.

In conclusion, piperidine-4-sulfonic acid stands out not only for its chemical properties but also for its extensive applications in research and industry. Its versatility and functionality make it a compound of great interest for chemists and biochemists alike.

Synonyms
piperidine-4-sulfonic acid
72450-62-5
Piperidine-4-sulphonic acid
4-Piperidinesulfonic acid
2M8K8ZJJ5U
P4S
CHEMBL34155
DTXSID70222752
MFCD00055097
Lopac-P-9159
UNII-2M8K8ZJJ5U
Lopac0_001024
MLS000069699
SCHEMBL106762
GTPL4287
DTXCID00145243
Piperidine-4-sulfonic acid (P4S)
BDBM50087272
PIPERIDINE-4-SULPHONIC ACID-
AKOS006272381
CCG-205104
NCGC00015855-01
NCGC00015855-02
NCGC00015855-03
NCGC00015855-04
NCGC00093348-02
NCGC00093348-03
DA-17251
SMR000058505
SY345650
HY-139116
CS-0179688
EU-0101024
G91881
P 9159
EN300-7550824
SR-01000075616
SR-01000075616-1
Q27088397
857-071-3