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Clonazepam

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Identification
Molecular formula
C15H10ClN2O3
CAS number
1622-61-3
IUPAC name
potassium;7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate
State
State
At room temperature, clonazepam is in a solid state as a powder.
Melting point (Celsius)
239.00
Melting point (Kelvin)
512.15
Boiling point (Celsius)
455.80
Boiling point (Kelvin)
728.95
General information
Molecular weight
315.71g/mol
Molar mass
315.7120g/mol
Density
2.0000g/cm3
Appearence
Clonazepam appears as a white to light yellow crystalline powder.
Comment on solubility

Solubility of Potassium 7-Chloro-2-Oxo-5-Phenyl-1,3-Dihydro-1,4-Benzodiazepine-3-Carboxylate

The solubility of potassium 7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate is an intriguing aspect of its chemical properties, with several factors influencing its behavior in different solvents.

Key Factors Affecting Solubility:

  • Polarity: The presence of polar functional groups within the compound can enhance solubility in polar solvents like water.
  • Ionic Interactions: The potassium ion (K+) can create favorable ionic interactions in aqueous solutions, promoting solubility.
  • Hydrophobic Interactions: Conversely, the phenyl group may contribute to hydrophobic interactions that can affect overall solubility.

In general, the solubility can be summarized as:

  1. High in Water: Due to ionic character associated with potassium ions.
  2. Moderate in Organic Solvents: Solubility might decrease in less polar solvents like ether or benzene.

It is essential to conduct specific tests to determine the exact solubility profile under varying conditions, as well as other factors such as temperature and pH, which can further influence solubility behaviors. Evaluating the solubility in different media is crucial for understanding its application in pharmaceutical formulations and biological systems.

Interesting facts

Interesting Facts about Potassium; 7-Chloro-2-Oxo-5-Phenyl-1,3-Dihydro-1,4-Benzodiazepine-3-Carboxylate

This compound, also known as a benzodiazepine derivative, falls under the category of psychoactive substances and has garnered significant interest in both medicinal chemistry and pharmacology.

Key Features:

  • Structural Diversity: The compound features a complex structure characterized by a benzodiazepine core, substituents that include a chlorine atom, a ketone group, and a phenyl ring. This arrangement contributes to its unique biological activity.
  • Therapeutic Potential: Benzodiazepines in general are known for their anxiolytic, sedative, and muscle relaxant properties. This specific compound may possess similar properties, potentially providing insights for drug design aimed at treating anxiety and related disorders.
  • Research Relevance: The compound's versatility makes it a subject of ongoing research, focusing on its pharmacokinetics, binding affinity to GABA receptors, and its potential side effects in comparison to other benzodiazepines.

One notable aspect of this compound is its potential mechanisms of action. According to studies, compounds like this one can enhance the effect of the neurotransmitter gamma-aminobutyric acid (GABA), leading to increased inhibitory activity in the central nervous system. This mechanism is pivotal for the sedative effects associated with benzodiazepines.

Quote to Consider:

As one researcher eloquently stated, “The exploration of benzodiazepine derivatives is a testament to the intricate dance between chemistry and neuropharmacology, where slight modifications can lead to vastly different therapeutic profiles.”

In conclusion, potassium; 7-chloro-2-oxo-5-phenyl-1,3-dihydro-1,4-benzodiazepine-3-carboxylate represents a fascinating intersection of organic chemistry and pharmacology, highlighting the importance of structural nuances in drug development.