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Prop-2-ynyl 3-(aziridin-1-yl)propanoate

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Identification
Molecular formula
C9H13NO2
CAS number
14830-13-2
IUPAC name
prop-2-ynyl 3-(aziridin-1-yl)propanoate
State
State

At room temperature, prop-2-ynyl 3-(aziridin-1-yl)propanoate is a liquid. It remains stable under normal atmospheric conditions but should be stored in a well-ventilated area away from sources of ignition due to its potential flammability.

Melting point (Celsius)
-3.00
Melting point (Kelvin)
270.00
Boiling point (Celsius)
296.00
Boiling point (Kelvin)
569.00
General information
Molecular weight
153.18g/mol
Molar mass
153.1800g/mol
Density
1.0910g/cm3
Appearence

Prop-2-ynyl 3-(aziridin-1-yl)propanoate is typically a colorless to pale yellow liquid. It may exhibit a slight odor depending on purity and formulation. The liquid tends to be clear but may appear slightly hazy if impurities or solvents are present.

Comment on solubility

Solubility of Prop-2-ynyl 3-(aziridin-1-yl)propanoate

Prop-2-ynyl 3-(aziridin-1-yl)propanoate, a compound with unique structural characteristics, exhibits noteworthy solubility traits that can influence its applications. Understanding its solubility is crucial for researchers and chemists. Here are some key points:

  • Solvent Interaction: The compound demonstrates varying solubility in different solvents. It is generally soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO), which can facilitate its use in various chemical reactions and applications.
  • Aqueous Solubility: In contrast, its solubility in water is limited. This characteristic can affect its bioavailability and potential use in pharmaceutical formulations.
  • Functional Groups: The presence of both the aziridine and propanoate moieties influences solubility. Functional groups can impact the polarity of the molecule, thus affecting how well the compound interacts with solvents.
  • Temperature Dependency: Like many organic compounds, solubility may increase with temperature. This factor can be critical during synthesis and formulation processes.

To summarize, while prop-2-ynyl 3-(aziridin-1-yl)propanoate shows promising solubility in specific organic solvents, its limited aqueous solubility may pose challenges in certain applications. Understanding these solubility profiles allows for better strategic planning in research and industrial applications.

Interesting facts

Interesting Facts about Prop-2-ynyl 3-(Aziridin-1-yl)propanoate

Prop-2-ynyl 3-(aziridin-1-yl)propanoate is a fascinating compound that belongs to the class of alkynes and is characterized by its unique aziridine functionality. Here are some highlighted features of this intriguing molecule:

  • Reactive Intermediate: Due to the presence of both an alkyne and an aziridine ring, prop-2-ynyl 3-(aziridin-1-yl)propanoate can serve as a versatile intermediate in organic synthesis, allowing chemists to design and develop new compounds.
  • Biological Activity: Compounds that contain aziridine rings often exhibit significant biological activity. Research has indicated that aziridines can exhibit antitumor properties, making this compound a candidate for potential pharmaceutical applications.
  • Use in Polymer Chemistry: The unique structure of prop-2-ynyl 3-(aziridin-1-yl)propanoate provides opportunities in the development of novel copolymers that possess desirable properties such as enhanced mechanical strength and thermal stability.
  • Synthesis Insight: The compound can be synthesized through various methods, including the reaction of propargyl alcohol with aziridine derivatives. This highlights the importance of functional group compatibility in organic transformations.
  • Application Potential: Given its capacity for electrophilic substitution, this compound could be utilized in the synthesis of other complex molecules that are of interest in medicinal chemistry.

As research into aziridine-containing compounds continues to grow, prop-2-ynyl 3-(aziridin-1-yl)propanoate stands out as a compound rich with potential applications in various fields, including pharmaceuticals and materials science. The continuing exploration of such compounds by chemists could lead to significant advancements in drug development and synthetic methodologies.

Synonyms
1-AZIRIDINEPROPIONIC ACID, 2-PROPYNYL ESTER
22480-28-0
9PA56VG9PS
NSC 101301
Propargyl 1-aziridinepropionate
1-Aziridinepropionic acid, propargyl ester
1-Aziridinepropanoic acid, 2-propynyl ester
UNII-9PA56VG9PS
NSC-101301
Propionic acid, 3-(1-aziridinyl)-, 2-propynyl ester
DTXSID00177009
1-AZIRIDINEPROPANOIC ACID, 2-PROPYN-1-YL ESTER
RefChem:202740
DTXCID2099500
NCIOpen2_001789
NSC101301