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1,3-Propanediol

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Identification
Molecular formula
C3H8O2
CAS number
504-63-2
IUPAC name
propane-1,3-diol
State
State
At room temperature, 1,3-Propanediol is in a liquid state. It is also highly soluble in water, which enhances its use in various industrial applications.
Melting point (Celsius)
-27.00
Melting point (Kelvin)
246.15
Boiling point (Celsius)
214.00
Boiling point (Kelvin)
487.15
General information
Molecular weight
76.10g/mol
Molar mass
76.0950g/mol
Density
1.0591g/cm3
Appearence

1,3-Propanediol is typically a colorless viscous liquid. It is often utilized in the production of polymers and can appear oily to the touch. In its pure form, it is clear and does not contain any significant impurities that might alter its appearance.

Comment on solubility

Solubility of Propane-1,3-diol

Propane-1,3-diol, also known as propylene glycol, is a hygroscopic organic compound with a unique solubility profile that makes it quite versatile in applications. Its chemical structure contributes to its ability to dissolve in various solvents. Here are some key points regarding its solubility:

  • Water Solubility: Propane-1,3-diol is highly soluble in water. Its polar hydroxyl groups (-OH) facilitate interactions with water molecules, enabling it to mix freely.
  • Solvent Versatility: Beyond water, propylene glycol also demonstrates excellent solubility in a variety of organic solvents. It easily dissolves in acetone, ethanol, and ethyl acetate, making it useful in numerous formulations.
  • Non-polar Solvents: However, it has limited solubility in non-polar solvents, such as hydrocarbons. This characteristic stems from its polar nature, which does not favor interactions with non-polar environments.
  • Temperature Influence: The solubility of propane-1,3-diol can also be influenced by temperature; generally, higher temperatures increase solubility in both water and organic solvents.

In summary, the solubility of propane-1,3-diol reflects its polar characteristics and makes it an invaluable compound in formulations requiring a soluble component. As one can see, the phrase "Like dissolves like" aptly describes its behavior, highlighting its affinity for polar solvents while demonstrating limitations with non-polar ones.

Interesting facts

Interesting Facts about Propane-1,3-diol

Propane-1,3-diol, commonly known as propylene glycol, is a fascinating compound with diverse applications across various industries. Here are some intriguing aspects of this compound:

  • Versatile Solvent: Propylene glycol is widely used as a solvent in pharmaceutical formulations and personal care products due to its ability to dissolve both hydrophilic and lipophilic substances.
  • Food Industry: It acts as a food additive, classified as generally recognized as safe (GRAS) by the FDA, and is used in food products as a humectant, preserving moisture and improving texture.
  • Hydrophilic Nature: The compound's hydrophilic nature makes it effective in attracting and retaining water, which is critical in numerous applications, especially in skin-care products where moisture retention is paramount.
  • Non-toxic: One of the key features of propane-1,3-diol is its low toxicity profile, making it suitable for use in consumables and pharmaceuticals, garnering trust among manufacturers and consumers alike.
  • Industrial Applications: Beyond food and pharmaceuticals, this compound is employed in antifreeze formulations and de-icing solutions due to its advantageous thermal properties.
  • Biological Compatibility: Its compatibility with biological materials allows it to be used in various medical applications, including as a carrier for drugs and a vehicle for injections.

In summary, propane-1,3-diol is not just another synthetic compound; it is a versatile and essential ingredient in many sectors. Its myriad of applications is a testament to the innovative use of chemical compounds in everyday life.

Synonyms
1,3-PROPANEDIOL
Propane-1,3-diol
504-63-2
Trimethylene glycol
1,3-Dihydroxypropane
1,3-Propylene glycol
2-Deoxyglycerol
1,3-PROPANDIOL
1,3-Propylenediol
2-(Hydroxymethyl)ethanol
beta-Propylene glycol
omega-Propanediol
.beta.-Propylene glycol
NSC 65426
.omega.-Propanediol
AI3-01851
HOCH2CH2CH2OH
HO(CH2)3OH
DTXSID8041246
CHEBI:16109
NSC-65426
5965N8W85T
345260-48-2
EINECS 207-997-3
MFCD00002949
BRN 0969155
UNII-5965N8W85T
3-hydroxypropanol
1,3 propanediol
1.3-propanediol
propane-1,3diol
propane1,3-diol
propane1.3-diol
1,3 propandiol
propan-1,3-diol
1,3 -propanediol
1,3- propanediol
1,3-propane diol
1,3-propane-diol
propane 1,3-diol
propane 1.3-diol
propane diol-1,3
propane-1-3-diol
propane-1.3-diol
Trimethylene glycol;
1,3-propyleneglycol
propane-1, 3-diol
propanediol-(1,3)
bmse000303
EC 207-997-3
1,3-Propanediol, 98%
1,3-Propanediol (Standard)
(HOCH2)2CH2
CH2(CH2OH)2
CHEMBL379652
DTXCID6021246
TRIMETHYLENE GLYCOL [MI]
HSDB 8263
1,3-Propanediol, >=99.6%
HY-W017758R
JLA47477
NSC65426
Tox21_300750
STL282728
AKOS000269061
CS-W018490
DB02774
FP33131
HY-W017758
NCGC00248157-01
NCGC00254655-01
BP-30193
CAS-504-63-2
PD007650
DB-071203
NS00005983
P0486
EN300-19343
1,3-Propanediol, puriss., >=99.0% (GC)
C02457
D77845
A828134
Q161514
InChI=1/C3H8O2/c4-2-1-3-5/h4-5H,1-3H
F1908-0064
Z104473578
7AB97F71-EF6B-4C05-8084-541427B9306C
1,3-Propanediol, United States Pharmacopeia (USP) Reference Standard
31714-45-1