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Propyl fluoroacetate

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Identification
Molecular formula
C5H9FO2
CAS number
459-72-3
IUPAC name
propyl 2-fluoroacetate
State
State

At room temperature, propyl fluoroacetate is a liquid. Its relatively low boiling point and high volatility make it suitable for use in certain chemical synthesis and industrial applications.

Melting point (Celsius)
-92.00
Melting point (Kelvin)
181.15
Boiling point (Celsius)
134.00
Boiling point (Kelvin)
407.15
General information
Molecular weight
134.14g/mol
Molar mass
134.1380g/mol
Density
1.0147g/cm3
Appearence

Propyl fluoroacetate is a colorless liquid with a fruity odor. It is important to handle it with care, as it is a volatile substance.

Comment on solubility

Solubility of Propyl 2-Fluoroacetate

Propyl 2-fluoroacetate, with the chemical formula C5H9F1O2, exhibits interesting solubility characteristics that are pertinent in various chemical applications. Understanding its solubility can provide insights into its behavior in different solvents.

Key Points Regarding Solubility:

  • Polarity: Due to the presence of both the ester functional group and the electronegative fluorine atom, propyl 2-fluoroacetate is polar in nature.
  • Solvent Compatibility: This compound is soluble in polar solvents such as water and alcohols, allowing it to be effectively utilized in aqueous solutions.
  • Hydrophobic Characteristics: While it is polar, the presence of the propyl group also gives it some hydrophobic character, making it less soluble in non-polar solvents.
  • Concentration Effects: The solubility can vary significantly with temperature and concentration, often increasing at elevated temperatures.

In summary, the solubility of propyl 2-fluoroacetate makes it a versatile compound in organic chemistry. Its polar nature allows for solubility in various solvents, which can be advantageous for reactions and applications in different media.

Interesting facts

Interesting Facts about Propyl 2-Fluoroacetate

Propyl 2-fluoroacetate is an intriguing compound that showcases the fascinating interplay of organic chemistry and industrial applications. Here are several engaging points about this compound:

  • Structure and Functionality: Propyl 2-fluoroacetate features a propyl group attached to a 2-fluoroacetate moiety. This unique structure allows it to behave both as a solvent and a reactant in various chemical reactions.
  • Industrial Relevance: This compound is extensively utilized in the synthesis of biologically active compounds. It plays a vital role in the production of pharmaceuticals, agrochemicals, and other specialty chemicals, highlighting its significance in the chemical industry.
  • Mechanism of Action: As a versatile building block, propyl 2-fluoroacetate can undergo various chemical transformations such as esterification, nucleophilic substitution, and even fluorination reactions. These processes make it a key intermediary in organic synthesis.
  • Biological Activity: Propyl 2-fluoroacetate has garnered attention for its potential biological activities, making it an interesting subject for studies in medicinal chemistry. Researchers continue to explore its pharmacological properties while aiming to understand its interactions at the molecular level.
  • Environmental Considerations: While beneficial in many applications, the use of propyl 2-fluoroacetate necessitates careful handling and adherence to environmental regulations. Understanding its environmental impact is crucial for sustainable chemical processes.

To summarize, propyl 2-fluoroacetate exemplifies the versatility and utility of organic compounds in both industrial and research settings. Its ability to participate in varied chemical reactions and its importance in the synthesis of biologically relevant molecules make it an exciting focus for chemists and students alike.

Synonyms
propyl 2-fluoroacetate
10117-11-0
ACETIC ACID, FLUORO-, PROPYL ESTER
n-Propyl fluoroacetate
BRN 1744815
propyl fluoroacetate
SCHEMBL2838461
DTXSID80143762
AT32526