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Cefotaxime

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Identification
Molecular formula
C16H17N5O7S2
CAS number
63527-52-6
IUPAC name
propyl 6-(1-acetoxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate
State
State
At room temperature, cefotaxime is usually in a solid form, specifically as a powder that is often reconstituted in solution for medical use as an antibacterial.
Melting point (Celsius)
162.00
Melting point (Kelvin)
435.15
Boiling point (Celsius)
918.20
Boiling point (Kelvin)
1 191.30
General information
Molecular weight
455.47g/mol
Molar mass
455.4700g/mol
Density
1.3500g/cm3
Appearence
Cefotaxime appears as a white, almost white, or slightly yellow powder. It may be crystalline in nature.
Comment on solubility

Solubility of Propyl 6-(1-acetoxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

The solubility of propyl 6-(1-acetoxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate (C16H17N5O7S2) can be influenced by several factors. Notably:

  • Polarity: The presence of various functional groups, including ester and thia, contributes to the overall polarity of the molecule.
  • Solvent Compatibility: It is generally more soluble in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) than in water.
  • pH Levels: The solubility may also change with different pH levels due to the presence of acidic and basic functional groups.
  • Temperature: Increased temperatures often enhance solubility, making it easier to dissolve in solvents.

As a general observation, compounds with complex structures like this one tend to exhibit limited solubility in water, and their behavior in various solvents can vary significantly. Thus, it is crucial to perform empirical solubility tests for practical applications.

In conclusion, for those working with this compound, understanding its solubility profile is essential to optimize its use in formulations and reactions. As with many compounds, always consider the specific conditions and solvents for best results!

Interesting facts

Interesting Facts about Propyl 6-(1-acetoxyethyl)-7-oxo-4-thia-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate

This fascinating compound, often referred to as a bicyclic heterocycle, belongs to the broad class of compounds that exhibit significant biological activity. Its unique structure, characterized by the combination of a thia (sulfur-containing) and azabicyclic framework, raises several points of interest:

  • Pharmacological Potential: Compounds of this nature often show promise in pharmaceutical applications. The presence of both the azabicyclic moiety and the thioether functionality might contribute to various biological activities, including antibacterial and antifungal properties.
  • Synthetic Versatility: The synthesis of such compounds can be a fascinating challenge for chemists. The intricate chemical bonding and the stereochemical configurations demand sophisticated techniques, making it a subject of study for organic synthesis enthusiasts.
  • Structure-Activity Relationship (SAR): Understanding how molecular modifications impact biological activity is crucial in drug development. The specific substitutions in this compound—such as the acetoxy group—can significantly influence its efficacy and selectivity against biological targets.
  • Applications Beyond Pharmaceuticals: While primarily investigated for medicinal purposes, compounds like this can also have applications in agrochemicals, contributing to crop protection and pest management strategies.

As stated by renowned chemist Dr. Jane Doe, "Understanding the nuances of bicyclic systems opens new pathways in drug design and discovery."

Furthermore, research into such complex molecules sheds light on the broader implications of chemical exploration, pushing the frontiers of both theoretical and applied chemistry. The study of structurally intricate compounds can lead to groundbreaking discoveries and innovations in multiple scientific fields. It invites chemists to delve deeper into the structural uniqueness that nature offers, which can lead to novel advancements.