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2-Aminopyridine

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Identification
Molecular formula
C5H6N2
CAS number
504-29-0
IUPAC name
pyridin-2-amine
State
State

At room temperature, 2-Aminopyridine is generally in the solid state. It forms crystalline structures that are stable under normal conditions.

Melting point (Celsius)
59.00
Melting point (Kelvin)
332.15
Boiling point (Celsius)
210.00
Boiling point (Kelvin)
483.15
General information
Molecular weight
94.11g/mol
Molar mass
94.1120g/mol
Density
1.1029g/cm3
Appearence

2-Aminopyridine appears as white or slightly beige crystalline solid, which can also manifest as flaky crystals. It has a distinct pyridine-like odor that can be noticeable when in its pure form.

Comment on solubility

Solubility of Pyridin-2-amine

Pyridin-2-amine, also known as 2-aminopyridine, is a heterocyclic organic compound that exhibits interesting solubility properties. It is a polar compound due to the presence of the amino group (-NH2) attached to the pyridine ring, which enhances its interaction with solvents. Here are some key points to consider regarding its solubility:

  • Solvent Compatibility: Pyridin-2-amine is typically soluble in water due to its polar nature, which allows it to readily form hydrogen bonds with water molecules.
  • Other Solvents: In addition to water, it is also soluble in alcohols and ethers, making it versatile for various chemical reactions and processes.
  • Temperature Effects: The solubility of pyridin-2-amine can increase with temperature, as is common with many organic compounds, allowing for greater dissolution in higher temperature environments.

In summary, pyridin-2-amine is a soluble compound in water and a variety of organic solvents, which contributes to its utility in various chemical applications. Its ability to interact with different solvents is a testament to its chemical structure and properties.

Interesting facts

Interesting Facts about Pyridin-2-amine

Pyridin-2-amine, often referred to as 2-aminopyridine, is a fascinating aromatic amine that showcases some intriguing properties and applications in various fields. Here are some key points that highlight the importance and versatility of this compound:

  • Structure and Properties: Pyridin-2-amine contains a pyridine ring substituted at the 2-position with an amino group. This positioning is crucial as it affects the compound's reactivity and interactions.
  • Chemical Reactivity: The amino group (-NH2) confers basic properties to the molecule, allowing it to participate in various chemical reactions, including nucleophilic substitutions and condensation reactions.
  • Biological Significance: Pyridin-2-amine derivatives have been the subject of extensive research due to their potential medicinal properties, including anti-inflammatory and neuroprotective effects. Researchers are exploring their potential as drug candidates in various therapeutic areas.
  • Synthetic Routes: There are several methods for synthesizing pyridin-2-amine, including the reduction of 2-cyanopyridine or direct amination of pyridine, showcasing the compound's accessibility for further chemical modification.
  • Applications in Material Science: Beyond organic chemistry and medicinal applications, pyridin-2-amine and its derivatives are being investigated for their use in creating advanced materials, such as polymers and functional coatings.

In conclusion, pyridin-2-amine stands as a compelling example of how simple organic compounds can lead to significant advancements in both scientific research and practical applications. As scientists continue to explore its potential, we may uncover even more exciting uses for this versatile compound.

Synonyms
2-AMINOPYRIDINE
504-29-0
pyridin-2-amine
2-Pyridinamine
2-Pyridylamine
Pyridinamine
Aminopyridine
o-Aminopyridine
2-aminopyridin
2-Aminopryidine
Pyridine, 2-amino-
Amino-2 pyridine
1,2-Dihydro-2-iminopyridine
2-Pyridinylnitrene
26445-05-6
Pyridin-2-ylamine
.alpha.-Aminopyridine
NSC 431
2-pyridinylamine
.beta.-Pyridylamine
pyridin-2-yl-amine
.alpha.-Pyridinamine
.alpha.-Pyridylamine
MFCD00006312
WSX981HEWU
CHEMBL21619
DTXSID0024505
NSC-431
2-amino pyridine
alpha-Pyridinamine
alpha-Pyridylamine
alpha-Aminopyridine
24843-39-8
Pyridin-2-amine (2-Pyridylamine)
Pyridine, amino-
CCRIS 4747
HSDB 2068
EINECS 207-988-4
UNII-WSX981HEWU
aminopyridin
iminopyridine
pyridineamine
pyridinylamine
Aminopyridines
amino pyridine
amino-pyridine
Pyridyl amine
pyridyl nitrogen
AI3-15287
|A-Pyridylamine
2-pyridyl amine
2-amino-pyridine
2-aminopyr-idine
pyridine-2-amine
pyridine-2-ylamine
aminopyridine, 2-
2-Aminopyridine, 99%
EC 207-988-4
2-Aminopyridine, >=99%
BIDD:GT0578
DTXCID404505
NSC431
2-AMINOPYRIDINE [HSDB]
JGQBNAFULRKENS-UHFFFAOYSA-N
.ALPHA.-AMINOPYRIDINE [MI]
BCP22964
STR00201
Tox21_200880
BBL011573
BDBM50013712
STK286012
AKOS000119615
CS-W020569
FA07684
PB47078
2-AP, 2-Pyridinamine, 2-Pyridylamine
o-Aminopyridine [UN2671] [Poison]
NCGC00248863-01
NCGC00258434-01
BP-13063
CAS-504-29-0
PD180348
PIROXICAM IMPURITY A [EP IMPURITY]
TENOXICAM IMPURITY A [EP IMPURITY]
2-Aminopyridine, purum, >=98.0% (NT)
DB-020545
A0411
NS00010856
EN300-19030
F90389
P17100
AC-907/25014346
2-Aminopyridine, PESTANAL(R), analytical standard
MEPYRAMINE MALEATE IMPURITY C [EP IMPURITY]
Q2393470
F1995-0206
PIROXICAM RELATED COMPOUND A, REFERENCE STANDARD
Z104472278
InChI=1/C5H6N2/c6-5-3-1-2-4-7-5/h1-4H,(H2,6,7
Mepyramine impurity C, European Pharmacopoeia (EP) Reference Standard