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3-Hydroxypyridine

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Identification
Molecular formula
C5H5NO
CAS number
109-00-2
IUPAC name
pyridin-3-ol
State
State

At room temperature, 3-Hydroxypyridine is a solid. It is typically handled in the form of a crystalline powder for laboratory and industrial applications.

Melting point (Celsius)
127.00
Melting point (Kelvin)
400.15
Boiling point (Celsius)
258.00
Boiling point (Kelvin)
531.15
General information
Molecular weight
95.10g/mol
Molar mass
95.1040g/mol
Density
1.2150g/cm3
Appearence

3-Hydroxypyridine, also known as pyridin-3-ol, is a white to off-white crystalline powder. It is often used in organic synthesis and has a distinct aromatic odor typical of pyridine and its derivatives.

Comment on solubility

Solubility of Pyridin-3-ol

Pyridin-3-ol, with the chemical formula C5H7NO, is known for its intriguing solubility characteristics. Here are some key points regarding its solubility:

  • Polarity: Pyridin-3-ol is a polar compound due to the presence of a hydroxyl (-OH) group. This feature enhances its ability to interact with water molecules.
  • Water Solubility: Pyridin-3-ol is generally soluble in water, making it useful in various chemical reactions and applications.
  • Organic Solvents: It is also soluble in many organic solvents such as ethanol, methanol, and acetone, which is beneficial for its use in organic synthesis.
  • Temperature Dependency: Like many organic compounds, its solubility can be affected by temperature. Typically, increasing the temperature may enhance its solubility in solvents.

As a polar compound, Pyridin-3-ol exemplifies how functional groups can significantly influence solubility. Its ability to dissolve in both water and organic solvents makes it versatile for various applications.

Interesting facts

Exploring Pyridin-3-ol

Pyridin-3-ol, also known as 3-hydroxypyridine, is an intriguing compound that bridges the worlds of organic chemistry and medicinal applications. This compound, characterized by its pyridine ring with a hydroxyl group at the third position, presents several fascinating aspects worth exploring:

  • Structural Significance: The presence of the hydroxyl group enhances its reactivity and makes it a valuable building block for various chemical syntheses.
  • Biological Activity: Pyridin-3-ol has been studied for its potential biological activities, including antibacterial, antifungal, and anticancer properties. This makes it a candidate for drug development.
  • Coordination Chemistry: It can serve as a ligand in coordination compounds, forming complexes with transition metals. These complexes can exhibit unique electronic and magnetic properties.
  • Industrial Applications: Pyridin-3-ol is utilized in the synthesis of agricultural chemicals, pharmaceuticals, and other organic substances, illustrating its wide range of practical uses.

A notable quote concerning its relevance in medicinal chemistry states, "Incorporating heterocycles such as pyridin-3-ol into drug design can lead to significant advances in therapeutic efficacy." This underscores the importance of this compound in the quest for new and effective medicines.

Overall, pyridin-3-ol stands as a testament to how a simple structural modification can lead to a compound with profound implications in both scientific research and practical applications.

Synonyms
3-HYDROXYPYRIDINE
pyridin-3-ol
109-00-2
3-Pyridinol
3-Pyridone
3-Pyridol
3-Oxopyridine
beta-Hydroxypyridine
m-Hydroxypyridine
3-Pyridyl alcohol
.beta.-Hydroxypyridine
UNII-4KBE4P5B6S
EINECS 203-637-4
MFCD00006378
NSC 18470
CHEBI:87440
AI3-19237
NSC-18470
4KBE4P5B6S
CHEMBL237847
SR-1C8
DTXSID1051563
3-hydoxypyridine
3-hydroxy pyridine
3-hydroxy-pyridine
mHydroxypyridine
PYRIDINE, 3-HYDROXY-
3hydroxypyridine
3Oxopyridine
3-oxypyridine
3Pyridone
3Pyridol
b-Hydroxypyridine
3Pyridyl alcohol
3-oxidopyridinium
betaHydroxypyridine
3-hydroxylpyridine
Pyridine-3-ol
3-HYDROXYPYRIDINE (3-PYRIDINOL)
3-Hydroxypyridine isomer
3-Hydroxypyridine, 98%
3-Pyridinol; Pyridin-3-ol
DTXCID5030115
BCP26364
HY-Y1129
NSC18470
STR00285
BBL010946
BDBM50225189
STK802047
AKOS000119647
BS-3731
CS-W009147
SB52272
BP-12457
PD158448
DB-016011
H0331
NS00000983
EN300-20091
D70736
3-Hydroxypyridine, Vetec(TM) reagent grade, 99%
AC-907/25014060
AC-907/25014061
Q223089
F1995-0197
Z104476790
467D3257-37E0-4666-B266-CF679BC6CE5A
71A
80618-81-1