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2-Pyridinecarboxaldehyde

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Identification
Molecular formula
C6H5NO
CAS number
1121-60-4
IUPAC name
pyridine-2-carbaldehyde
State
State
At room temperature, 2-pyridinecarboxaldehyde is typically found in liquid form.
Melting point (Celsius)
-28.00
Melting point (Kelvin)
245.15
Boiling point (Celsius)
184.00
Boiling point (Kelvin)
457.15
General information
Molecular weight
107.11g/mol
Molar mass
107.1070g/mol
Density
1.1150g/cm3
Appearence

2-Pyridinecarboxaldehyde is a liquid with a pale yellow color. It has a distinct pyridine-like odor. The liquid is usually clear and free-flowing.

Comment on solubility

Solubility of Pyridine-2-carbaldehyde

Pyridine-2-carbaldehyde, also known as 2-pyridinecarboxaldehyde, is a compound that exhibits notable solubility characteristics. It is predominantly soluble in polar solvents, where its properties can be traced back to the functional groups present in its structure.

In terms of solubility:

  • Solvent Compatibility: Pyridine-2-carbaldehyde readily dissolves in water, ethanol, and acetone due to its polarity.
  • Hydrophobic vs. Hydrophilic: The presence of the aldehyde group enhances its hydrophilic nature, facilitating solubility in polar environments.
  • Concentration Considerations: Its solubility can vary with concentration, temperature, and the presence of other solutes.

As a result of these features, Pyridine-2-carbaldehyde stands out in organic chemistry for its versatility in reactions involving both polar and non-polar solvents. Thus, understanding its solubility profile is crucial for effective applications in synthesis and laboratory practices.

Interesting facts

Interesting Facts about Pyridine-2-Carbaldehyde

Pyridine-2-carbaldehyde, also known as 2-pyridinecarboxaldehyde, is a fascinating compound with unique applications and characteristics that draw the interest of chemists and researchers alike. Here are some intriguing insights about this compound:

  • Structure and Properties: Pyridine-2-carbaldehyde features a pyridine ring, which is a six-membered aromatic ring containing one nitrogen atom. This nitrogen atom significantly influences the compound’s reactivity and properties.
  • Reactivity: As an aldehyde, it possesses a highly reactive carbonyl group. This enables pyridine-2-carbaldehyde to participate in various chemical reactions, including nucleophilic additions and condensation reactions.
  • Applications: This compound is widely utilized in the synthesis of heterocyclic compounds and as an intermediate in the production of pharmaceuticals, agrochemicals, and dyes. Its potential as a building block in organic synthesis is highly regarded.
  • Biological Significance: Pyridine-2-carbaldehyde has demonstrated biological activities, showing promise in medicinal chemistry. Some derivatives of this compound exhibit antimicrobial and anti-cancer properties.
  • Flavor and Fragrance Industry: Its aromatic properties make it a subject of interest in the flavor and fragrance industry, where it may be used to produce various scent profiles.

Overall, pyridine-2-carbaldehyde is a compound that bridges the gap between organic chemistry and applied sciences, making it a valuable research subject for those studying chemical synthesis and biological applications. As a versatile building block, it continues to play a significant role in advancing multiple fields of study.

Synonyms
2-Pyridinecarboxaldehyde
Picolinaldehyde
1121-60-4
Pyridine-2-carbaldehyde
2-Formylpyridine
Pyridine-2-aldehyde
Picolinal
2-Picolinaldehyde
2-Pyridaldehyde
o-Nicotinaldehyde
Picolinic aldehyde
2-Picolinealdehyde
2-Pyridylaldehyde
2-Pyridylcarboxaldehyde
2-Pyridinecarbaldehyde
alpha-Picolinaldehyde
2-pyridylformaldehyde
.alpha.-Picolinaldehyde
NSC 8951
KH86K8FHZ2
CHEBI:73012
NSC-8951
EINECS 214-333-6
AI3-33230
DTXSID1061522
EC 214-333-6
2Formylpyridine
oNicotinaldehyde
2Pyridaldehyde
2Picolinaldehyde
2Pyridylaldehyde
2Picolinealdehyde
Pyridine2aldehyde
2pyridylcarboxaldehyde
2pyridinecarboxaldehyde
Picolinaldehyde (8CI)
DTXCID3033276
214-333-6
inchi=1/c6h5no/c8-5-6-3-1-2-4-7-6/h1-5
Pyridine-2-carboxaldehyde
Pyridinecarboxaldehyde
26445-06-7
2-Pyridine carboxaldehyde
MFCD00006290
2-formyl-pyridine
2-Pyridinealdehyde
pyridine, 2-formyl-
formylpyridine
picolinealdehyde
picolin aldehyde
carbonyl-pyridine
picoline aldehyde
pyridine aldehyde
2-formyl pyridine
Pyridinecarbaldehyde
2-Pyridinecarboxaldehyde; 2-Formylpyridine; 2-Picolinaldehyde; 2-Pyridaldehyde; Picolinic Aldehyde; Pyridine-2-aldehyde
pyridincarboxaldehyde
2-pyridine aldehyde
2-pyridylcarbaldehyde
pyridine-carboxaldehyde
2-pyridinecarboaldehyde
2-pyridinecarboxaldeyde
pyridin-2-carbaldehyde
pyridin-2-yl-methanone
pyridine-2 carbaldehyde
pyridine-2-formaldehyde
pyridine2-carboxaldehyde
2-pyridyl carboxaldehyde
2-pyridyl-carboxaldehyde
(pyridin-2-yl)methanone
2-pyridine-carboxaldehyde
pyridine 2-carboxaldehyde
UNII-KH86K8FHZ2
SCHEMBL55278
SCHEMBL730714
2-Pyridinecarboxaldehyde, 99%
CHEMBL274794
PYRIDIN-2-CARBOXALDEHYDE
2-Formylpyridine, Picolinaldehyde
NSC8951
Picolinaldehyde;Pyridine-2-aldehyde
BCP21804
BBL027574
STL146657
AKOS000119317
AB00680
AC-5098
CS-W007336
FP05593
PS-9301
DB-015971
NS00005186
P0425
EN300-18999
A20908
D77679
doi:10.14272/CSDSSGBPEUDDEE-UHFFFAOYSA-N.1
Q4596887
F2190-0594
Z104472152
Picolinaldehyde; 2-Pyridinecarbaldehyde; Pyridine-2-aldehyde