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Pyridine-2-carbaldehyde oxime

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Identification
Molecular formula
C6H6N2O
CAS number
1003-74-9
IUPAC name
pyridine-2-carbaldehyde oxime
State
State

At room temperature, pyridine-2-carbaldehyde oxime is in a solid state.

Melting point (Celsius)
71.50
Melting point (Kelvin)
344.65
Boiling point (Celsius)
251.00
Boiling point (Kelvin)
524.00
General information
Molecular weight
122.13g/mol
Molar mass
122.1280g/mol
Density
1.1300g/cm3
Appearence

Pyridine-2-carbaldehyde oxime is typically a crystalline solid with a white to pale yellow appearance. It may appear as needles or prismatic crystals.

Comment on solubility

Solubility of Pyridine-2-carbaldehyde Oxime

Pyridine-2-carbaldehyde oxime, a compound with the formula C6H6N2O, displays unique solubility characteristics that are important for its applications in chemical reactions and synthesis.

In terms of solubility, you may observe the following:

  • Polar Solvent Compatibility: Pyridine-2-carbaldehyde oxime is generally soluble in polar solvents such as water and alcohols due to the presence of its hydroxyl (–OH) group, which enhances its interaction with polar molecules.
  • Limited Non-Polar Solubility: Conversely, its solubility is significantly reduced in non-polar solvents like hexane or toluene, owing to the lack of favorable interactions between the non-polar solvent molecules and the polar functional groups present in the compound.
  • Temperature Effects: The solubility can also vary with temperature; generally, higher temperatures will increase the solubility of organic compounds, including pyridine-2-carbaldehyde oxime.

It is important to note that the pH of the solution can influence the solubility since oxime compounds may undergo tautomerization, leading to different solubility profiles in various pH conditions.

In conclusion, while pyridine-2-carbaldehyde oxime is soluble in many polar solvents, its solubility is substantially lower in non-polar environments. Understanding its solubility profile is essential for effective utilization in chemical processes.

Interesting facts

Interesting Facts about Pyridine-2-Carbaldehyde Oxime

Pyridine-2-carbaldehyde oxime is a fascinating organic compound that belongs to a class of compounds known as oximes. This compound has garnered attention in various fields including synthetic chemistry, pharmaceuticals, and materials science. Here are some notable aspects:

  • Chemical Structure: Pyridine-2-carbaldehyde oxime features a unique structure where a pyridine ring is substituted with a carbaldehyde and an oxime functional group, making it an excellent candidate for chemical transformations and further reactions.
  • Synthon Importance: The compound serves as a useful synthon in organic synthesis, especially in the production of more complex molecules. Its reactivity allows it to participate in various chemical reactions, including condensation and substitution reactions.
  • Biological Activity: Compounds containing oxime groups have been studied for their potential biological activities. Pyridine-2-carbaldehyde oxime may demonstrate interesting properties that could lead to the development of novel pharmaceuticals.
  • Coordination Chemistry: The oxime functional group in this compound can coordinate with metal ions, making pyridine-2-carbaldehyde oxime a valuable ligand in coordination chemistry and catalysis.
  • In the Lab: Safety precautions should always be considered when handling this compound. It’s essential to follow proper laboratory protocols and utilize personal protective equipment (PPE) to ensure safe handling.

In summary, pyridine-2-carbaldehyde oxime is more than just a simple compound; it plays a significant role in the realm of organic synthesis and potential medicinal chemistry. As researchers continue to explore its reactivity and applications, we may uncover even more significant uses for this intriguing compound.

Synonyms
873-69-8
(E)-Picolinaldehyde oxime
1193-96-0
2-pyridinecarboxaldehyde oxime
(E)-pyridine-2-aldoxime
N-(Pyridin-2-ylmethylidene)hydroxylamine
N-[(Pyridin-2-yl)methylidene]hydroxylamine
Pyridine-2-carboxaldoxime
syn-Pyridine-2-aldoxime
(Z)-pyridine-2-aldoxime
pyridyl-nitrone
MFCD00006354
pyridine aldoxime
(Z)-N-[(pyridin-2-yl)methylidene]hydroxylamine
pyridin-2-carbaldehyde-oxime
2-hydroxyiminomethyl-pyridine
SCHEMBL103202
Pyridine-2-carboxaldehyde oxime
SCHEMBL18241563
DTXSID90922929
MTFJSAGADRTKCI-UHFFFAOYSA-N
VRGKDCRTYBCJTA-WAYWQWQTSA-N
DTXSID501007484
AKOS017263155
SB52235
SY016016
SY307853
2-(Nitrosomethylidene)-1,2-dihydropyridine
DB-056995
NS00042184
P0672