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Quinolinic acid

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Identification
Molecular formula
C7H5NO4
CAS number
89-00-9
IUPAC name
pyridine-2,3-dicarboxylic acid
State
State

At room temperature, quinolinic acid is a solid crystalline material. It is typically stored in this form under dry conditions to prevent degradation.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.00
Boiling point (Celsius)
653.00
Boiling point (Kelvin)
926.00
General information
Molecular weight
167.11g/mol
Molar mass
167.1130g/mol
Density
1.6200g/cm3
Appearence

Quinolinic acid appears as a colorless crystalline solid. The compound can also be found in various hydrated forms.

Comment on solubility

Solubility of Pyridine-2,3-dicarboxylic Acid

Pyridine-2,3-dicarboxylic acid (C7H5NO4), also known as 2,3-pyridinedicarboxylic acid, exhibits interesting solubility properties that are important for various applications.

When considering its solubility, it is noteworthy that:

  • Solvent Dependence: Pyridine-2,3-dicarboxylic acid is generally soluble in polar solvents such as water and ethanol due to its ability to form hydrogen bonds.
  • pH Influence: The solubility can significantly increase in basic conditions where the carboxylic acid groups become deprotonated, enhancing its ionization.
  • Temperature Effects: Like many organic compounds, increased temperatures can enhance solubility, making it easier for the acid to dissolve in various solvents.
  • Crystallization: Its solubility characteristics may also lead to crystallization at lower temperatures, creating solid-state forms that possess distinct solubility profiles.

In summary, the solubility of pyridine-2,3-dicarboxylic acid is influenced by factors such as the solvent type, pH, temperature, and concentration, making it a versatile compound in chemical reactions and formulations.

Interesting facts

Pyridine-2,3-dicarboxylic Acid: A Versatile Compound

Pyridine-2,3-dicarboxylic acid, commonly known as quinate, is an intriguing compound that serves as an essential building block in various chemical applications. This molecule possesses a pyridine ring with two carboxylic acid groups, which not only contributes to its distinctive properties but also enhances its functional versatility.

Interesting Facts

  • Biological Significance: Pyridine-2,3-dicarboxylic acid is often involved in metabolic processes in living organisms, acting as an intermediate in the biosynthesis of important biomolecules.
  • Applications in Medicine: This compound has shown potential in pharmaceutical research, particularly within the realm of drug design and synthesis.
  • Coordination Chemistry: The presence of the carboxylic acid groups allows for the formation of coordination complexes with various metal ions, making it a valuable ligand in organometallic chemistry.
  • Regulatory Role: It contributes to the regulation of pH levels in biological systems and is essential in maintaining cellular homeostasis.
  • Industrial Uses: Pyridine-2,3-dicarboxylic acid is used in agriculture as a herbicide and in the synthesis of certain dyes and polymers, illustrating its broad industrial relevance.

Furthermore, the ability of pyridine-2,3-dicarboxylic acid to engage in hydrogen bonding and other intermolecular interactions adds to its functionality, making it a versatile candidate for various research and industrial applications.
As a compound, it encompasses a rich interplay of chemistry, biology, and industry, underscoring the importance of exploring its potential in future scientific inquiries.

Synonyms
quinolinic acid
Pyridine-2,3-dicarboxylic acid
2,3-pyridinedicarboxylic acid
89-00-9
quinolinate
339155-13-4
AI3-63017
2,3-pyridine dicarboxylic acid
pyridinedicarboxylic acid
F6F0HK1URN
Pyridine-2,3-dicarboxylate
EINECS 201-874-8
MFCD00006295
NSC 13127
C7H5NO4
DTXSID8041327
CHEBI:16675
HSDB 7511
pyridine-2,3-carboxylate
NSC-13127
QUINOLINIC ACID [MI]
CHEMBL286204
28605-84-7
DTXCID6021327
EC 201-874-8
NSC 13127(ChemID)
NSC 13127[ChemID]
2,3-pyridinedicarboxylate
2,3-Pyridinedicarboxylicacid, labeled with tritium (9CI)
Pyridine-2,3-dicarboxylic acid(ChemID)
Pyridine-2,3-dicarboxylic acid[ChemID]
SMR000112287
SR-01000075472
UNII-F6F0HK1URN
quinolinic-acid
Spectrum_001525
Tocris-0225
pyridine carboxylate, 6c
Spectrum2_000929
Spectrum3_001502
Spectrum4_000336
Spectrum5_001170
Lopac-P63204
bmse000219
pyridine, 2,3-dicarboxy-
Quinolinic acid (Standard)
Pyridin-2,3-dicarbonsaeure
2,3Pyridinedicarboxylic acid
Lopac0_000989
Oprea1_139764
Pyridine2,3dicarboxylic acid
SCHEMBL69230
BSPBio_003143
KBioGR_000711
KBioSS_002005
MLS001332417
MLS001332418
MLS002153210
DivK1c_000773
Pyridine-2,3-dicarboxylicacid
SPECTRUM1502102
SPBio_000838
pyridine-5,6-dicarboxylic acid
BDBM26115
HMS502G15
KBio1_000773
KBio2_002005
KBio2_004573
KBio2_007141
KBio3_002643
NINDS_000773
HMS1921J12
HMS2267B04
HMS3263E19
HMS3266C15
HMS3411C05
HMS3675C05
HMS3885A17
NSC13127
NSC18836
Tox21_302051
Tox21_500989
BBL007601
CCG-39677
HB0544
NSC-18836
NSC403247
PDSP1_000133
PDSP2_000132
s3624
STK365157
2,3-Pyridinedicarboxylic acid, 99%
AKOS000119760
CS-W020665
DB01796
FG-0461
FP27303
HY-100807R
LP00989
NSC-403247
PB47350
SDCCGMLS-0411909.P028
SDCCGSBI-0050962.P003
CAS-89-00-9
IDI1_000773
MLS-0411909
NCGC00015865-01
NCGC00015865-02
NCGC00015865-03
NCGC00015865-04
NCGC00015865-05
NCGC00015865-06
NCGC00015865-07
NCGC00015865-08
NCGC00015865-12
NCGC00024506-01
NCGC00024506-02
NCGC00024506-03
NCGC00024506-04
NCGC00024506-05
NCGC00024506-06
NCGC00255468-01
NCGC00261674-01
AC-11734
SY003044
2,3-Pyridinedicarboxylic acid (8CI,9CI)
MLS-0411909.P016
DB-016184
HY-100807
EU-0100989
NS00006026
P0550
EN300-18090
C03722
D70926
P63204
AC-907/25014157
AE-641/00369043
Q411945
SR-01000075472-1
SR-01000075472-3
BRD-K51885093-001-11-2
Z57160166
F2191-0231
2,3-Pyridinedicarboxylic acid, Vetec(TM) reagent grade, 98%
Quinolinic acid;Pyridine-2,3-dicarboxylic acid;Pyridin-2,3-dicarbonsaeure