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2,5-Diaminopyridine

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Identification
Molecular formula
C5H7N3
CAS number
141-86-6
IUPAC name
pyridine-2,5-diamine
State
State
At room temperature, 2,5-Diaminopyridine is generally a solid.
Melting point (Celsius)
144.00
Melting point (Kelvin)
417.15
Boiling point (Celsius)
318.00
Boiling point (Kelvin)
591.15
General information
Molecular weight
109.13g/mol
Molar mass
109.1300g/mol
Density
1.2110g/cm3
Appearence

2,5-Diaminopyridine typically appears as a white to beige crystalline solid. It may also be encountered as a powder form, depending on its purity and preparation.

Comment on solubility

Solubility of Pyridine-2,5-diamine

Pyridine-2,5-diamine, also known by its systematic name 2,5-diaminopyridine, is a heterocyclic organic compound with distinctive solubility characteristics.

Water Solubility

This compound exhibits decent solubility in water, which can be attributed to the presence of amino groups that can form hydrogen bonds with water molecules. Here are some key points regarding its solubility:

  • Hydrogen Bonding: The amino groups (-NH2) enhance its solubility through hydrogen bonding interactions.
  • Concentration Effects: Solubility can increase with temperature, making it more soluble in warm water.
  • pH Influence: The solubility profile can change with pH levels, as protonation of the amine groups can enhance solubility in acidic conditions.

Solvent Affinity

Beyond water, pyridine-2,5-diamine is known to dissolve well in various organic solvents, making it versatile for a range of applications. Its affinity for solvents includes:

  • Organic Solvents: Good solubility in alcohols and polar aprotic solvents like DMSO.
  • Limited in Non-Polar Solvents: It shows poor solubility in non-polar solvents due to its polar nature.

In conclusion, the solubility of pyridine-2,5-diamine is influenced by multiple factors including temperature, pH, and the nature of solvents. Its ability to interact with water and other solvents through hydrogen bonding and dipole interactions makes it a noteworthy compound in chemical applications.

Interesting facts

Interesting Facts about Pyridine-2,5-Diamine

Pyridine-2,5-diamine, often recognized for its unique structure and properties, has made significant contributions to various fields of chemistry, particularly in pharmaceuticals and agrochemicals. Here are some intriguing aspects of this compound:

  • Structural Characteristics: Pyridine-2,5-diamine features a pyridine ring that is complemented by amino groups at the 2nd and 5th positions. This unique substitution pattern influences its reactivity and interactions.
  • Biological Significance: This compound is known for its potential role in drug synthesis, where it serves as a key building block in the production of several bioactive molecules.
  • Catalytic Applications: Pyridine derivatives, including pyridine-2,5-diamine, are utilized in coordination chemistry as ligands in catalysts, aiding in the transformation of substrates in various reactions.
  • Research Interest: Organic chemists are particularly interested in this compound due to its ability to act as a nucleophile, allowing it to participate in a range of chemical reactions such as nucleophilic substitutions and coupling reactions.
  • Environmental Implications: Its derivatives are also studied for use in agriculture as herbicides and fungicides, demonstrating efficacy in pest management systems.

In summary, pyridine-2,5-diamine is not just an ordinary compound; its multifaceted roles in research, pharmaceuticals, and agriculture underscore its importance in both scientific and practical applications. As scientists continue to explore its potential, it emphasizes the critical balance between innovation and environmental stewardship.

“The pursuit of understanding chemical nature is what distinguishes chemistry from mere observation.” — Anonymous

Synonyms
2,5-DIAMINOPYRIDINE
4318-76-7
PYRIDINE-2,5-DIAMINE
2,5-Pyridinediamine
Pyridine, 2,5-diamino-
H6OLZ060HI
NSC 175741
BRN 0108741
NSC-175741
DTXSID20195765
5-22-11-00252 (Beilstein Handbook Reference)
J51.294J
2,5-Pyridinediamine (9CI)
DTXCID60118256
626-246-4
MFCD00129023
2 pound not5-Diaminopyridine
UNII-H6OLZ060HI
Pyridine,5-diamino-
2,5-diamino pyridine
2,5-diamino-pyridine
WLN: T6NJ BZ EZ
SCHEMBL34048
YSZC148
2,5-Diaminopyridine, 97%
SCHEMBL24077008
GEO-04049
NSC175741
AKOS007930448
AC-5938
CS-W011281
SB75612
AS-13208
DA1
FD153008
SY030543
DB-031536
EN300-156258
AC-907/25014078
Q27279708
Z385438796