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Dipicolinic acid

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Identification
Molecular formula
C7H5NO4
CAS number
499-83-2
IUPAC name
pyridine-2,6-dicarboxylic acid
State
State

At room temperature, dipicolinic acid exists as a solid. This state is typical for small organic acids composed of aromatic rings and carboxylic functional groups.

Melting point (Celsius)
250.00
Melting point (Kelvin)
523.15
Boiling point (Celsius)
276.00
Boiling point (Kelvin)
549.15
General information
Molecular weight
167.12g/mol
Molar mass
167.1200g/mol
Density
1.4785g/cm3
Appearence

Dipicolinic acid is a white crystalline solid. It is typically available as a powder and is noted for its high water solubility. The compound may have a slight dipyridyl odor, depending on its purity and form.

Comment on solubility

Solubility of Pyridine-2,6-dicarboxylic Acid

Pyridine-2,6-dicarboxylic acid, known for its intriguing chemical properties, exhibits notable solubility characteristics that are of interest in various applications. The solubility of this compound can be affected significantly by factors such as temperature and the presence of solvents. Here are some key points to consider:

  • Water Solubility: Pyridine-2,6-dicarboxylic acid is moderately soluble in water. This is largely attributed to its ability to form hydrogen bonds with water molecules, enhancing its solubility.
  • Polar Solvents: The compound shows improved solubility in polar organic solvents, which can often dissolve carboxylic acids effectively. Examples include methanol and ethanol.
  • Non-polar Solvents: In contrast, pyridine-2,6-dicarboxylic acid demonstrates low solubility in non-polar solvents like hexane or benzene, due to its polar functional groups.

To sum up, when discussing the solubility of pyridine-2,6-dicarboxylic acid, it is crucial to focus on the type of solvent used. In the words of chemical solubility principles, “like dissolves like,” indicating that solvents sharing similar polarity with the compound will generally lead to higher solubility.

In practical scenarios, understanding these solubility dynamics is essential for optimizing the usage of pyridine-2,6-dicarboxylic acid in both academic research and industrial applications.

Interesting facts

Interesting Facts about Pyridine-2,6-dicarboxylic Acid

Pyridine-2,6-dicarboxylic acid, often referred to as 2,6-pyridinedicarboxylic acid, is an intriguing compound in the realm of organic chemistry. Here are some captivating aspects of this chemical:

  • Structural Significance: This compound features a pyridine ring, which is a six-membered aromatic ring consisting of five carbon atoms and one nitrogen atom. The presence of two carboxylic acid groups at the 2 and 6 positions significantly increases its reactivity and potential applications.
  • Applications in Synthesis: Pyridine-2,6-dicarboxylic acid is pivotal in the synthesis of various pharmaceuticals, agrochemicals, and dyes, showcasing the versatility of compounds derived from heterocyclic structures.
  • Building Block for Coordination Compounds: This compound serves as a valuable ligand in coordination chemistry, forming stable complexes with metal ions, which are used in catalysis and material science.
  • Biological Relevance: Notably, derivatives of pyridine-2,6-dicarboxylic acid have been studied for their potential biological activities, including antimicrobial and antitumor effects, making them of interest in medicinal chemistry.
  • Environmental Role: Due to its carboxylic acid groups, this compound can participate in various chemical processes in the environment, indicating a role in both natural and artificial systems.

In summary, pyridine-2,6-dicarboxylic acid is not just a simple aromatic compound; its unique structural features and functional groups open doors to numerous scientific explorations and innovative applications in chemistry and beyond. As noted by researchers, "Compounds like pyridine-2,6-dicarboxylic acid remind us of the intricate relationships between structure, function, and application in the chemical world."

Synonyms
2,6-Pyridinedicarboxylic acid
499-83-2
PYRIDINE-2,6-DICARBOXYLIC ACID
Dipicolinic acid
2,6-pyridinedicarboxylate
NSC 176
UNII-UE81S5CQ0G
EINECS 207-894-3
DTXSID7022043
CHEBI:46837
NSC-176
2,6-DIPICLINIC ACID
6-CARBOXYPICOLINIC ACID
DTXCID602043
2,6-DI-CARBOXY-PYRIDINE
Pyridinedicarboxylic acid-(2,6)
zinc dipicolinate
2,6-Pyridinedicarboxylic acid-2,6-dipicolinic acid
calcium dipicolinic acid
3,4-pyridinedicarboxylate
dipicolinic acid, zinc salt
dipicolinic acid, calcium salt
dipicolinic acid, disodium salt
dipicolinic acid, monosodium salt
dipicolinic acid, dipotassium salt
2,6-Dipicolinate
2,6Dipicolinic acid
Pyridine2,6dicarboxylic acid
inchi=1/c7h5no4/c9-6(10)4-2-1-3-5(8-4)7(11)12/h1-3h,(h,9,10)(h,11,12
wjjmndumqpnecx-uhfffaoysa-n
2,6-Dipicolinic acid
Dipicolinate
2,6-Dicarboxypyridine
MFCD00006299
UE81S5CQ0G
CHEMBL284104
2,6-Pyridinedicarboxylic acid, 99%
2,6-pyridine dicarboxylic acid
pyridine-2
pydcH2
Dipicolinic acid;DPA
4ih3
pyridine carboxylate, 6d
pyridine, 2,6-dicarboxy-
2,6-pyridinedicarboxylic acid (dipicolinic acid)
Oprea1_533632
SCHEMBL34595
MLS000080748
IFLab1_001781
NSC176
Dipicolinic acid, Beauveria sp.
BDBM26116
HMS1417A21
HMS2231H20
HY-Y1024
Tox21_301129
AC-704
BBL012080
CCG-44216
CL0252
STK092939
PYRIDINE-2,6-DICARBOXYLICACID
AKOS000112829
DB04267
FP34525
PS-8736
NCGC00071864-02
NCGC00255028-01
CAS-499-83-2
SMR000034075
SY001460
DB-015930
CS-0016012
EU-0033484
NS00013573
P0554
EN300-18133
Q417164
SR-01000600024-2
L-042,134
Z57202012
B63A70CE-B9AB-4EA2-834A-6C7634226BB0
F0451-0137
2,6-Pyridinedicarboxylic acid, for ion chromatography, >=99.5% (T)