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Quinolinic acid

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Identification
Molecular formula
C7H5NO4
CAS number
89-00-9
IUPAC name
pyridine-3,4-dicarboxylic acid
State
State

This compound is solid at room temperature.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.20
Boiling point (Celsius)
529.50
Boiling point (Kelvin)
802.70
General information
Molecular weight
167.12g/mol
Molar mass
167.1220g/mol
Density
1.6650g/cm3
Appearence

Quinolinic acid appears as a colorless to white crystalline solid.

Comment on solubility

Solubility of Pyridine-3,4-dicarboxylic Acid

Pyridine-3,4-dicarboxylic acid, with the formula C7H6N2O4, exhibits interesting solubility characteristics that are influenced by its carboxylic acid functional groups. This compound is known for its ability to dissolve in various polar solvents, primarily due to hydrogen bonding and electrostatic interactions. Below are key points regarding the solubility profile of pyridine-3,4-dicarboxylic acid:

  • Water Solubility: Pyridine-3,4-dicarboxylic acid is generally soluble in water, especially at elevated temperatures. Its polar carboxylic groups enhance interactions with water molecules.
  • Solvent Compatibility: This compound is soluble in a wide range of organic solvents such as ethanol and methanol, which are also polar, allowing for effective solvation.
  • pH Dependency: The solubility can vary with pH; at lower pH values, increased protonation of the carboxyl groups may limit solubility, while at higher pH values, deprotonation can improve solubility.
  • Temperature Effects: As with many solids, increased temperature typically boosts the solubility of pyridine-3,4-dicarboxylic acid.

In summary, the solubility of pyridine-3,4-dicarboxylic acid is a remarkable aspect of its chemistry, allowing for its use in various applications where solubility plays a critical role. Whether in aqueous solutions or organic media, understanding its solubility can aid in its effective utilization in research and industry.

Interesting facts

Interesting Facts About Pyridine-3,4-Dicarboxylic Acid

Pyridine-3,4-dicarboxylic acid, commonly known as quinaldic acid, is a fascinating compound belonging to the family of heterocyclic carboxylic acids. Its unique structure and properties make it significant in various fields, including pharmaceuticals and agrochemicals.

Key Features:

  • Structural Importance: The presence of two carboxylic acid groups in the pyridine ring enables the compound to engage in diverse chemical reactions. This allows it to be a versatile intermediate for synthesizing more complex molecules.
  • Biological Activity: Quinaldic acid has been identified to exhibit various biological activities, including antimicrobial and anti-inflammatory properties. These characteristics make it a target for developing new therapeutic agents.
  • Industrial Uses: The compound serves as an essential building block in the synthesis of dyes, flavors, and fragrances, enhancing the appeal of everyday products.
  • Research Applications: Pyridine-3,4-dicarboxylic acid is extensively studied for its potential application in drug development, owing to its ability to interact with biological systems effectively.
  • Important Derivatives: Modifications of quinaldic acid can lead to various derivatives that find uses in agriculture, particularly as herbicides and fungicides, showcasing its versatility.

As stated by notable chemists, "Understanding the chemistry of pyridine derivatives can unlock various pathways for innovation in multiple sectors from healthcare to environmental science." This highlights the compound's role in contributing to advancements in contemporary research.


In conclusion, pyridine-3,4-dicarboxylic acid is not just a simple organic compound; its multifaceted applications, from pharmaceuticals to industrial processes, make it an intriguing subject of study in the world of chemistry.

Synonyms
Pyridine-3,4-dicarboxylic acid
3,4-Pyridinedicarboxylic acid
490-11-9
CINCHOMERONIC ACID
Chinchomeronic acid
7389UZW5DY
CHEBI:46860
NSC 178
NSC-178
EINECS 207-705-4
CINCHOMERONIC ACID [MI]
DTXSID70197653
DTXCID30120144
207-705-4
inchi=1/c7h5no4/c9-6(10)4-1-2-8-3-5(4)7(11)12/h1-3h,(h,9,10)(h,11,12
Pyridine-3,4-dicarboxylicacid
MFCD00006392
3,4-Pyridinedicarboxylicacid
UNII-7389UZW5DY
Cinchomeronsaure
pyridine carboxylate, 6e
pyridine, 3,4-dicarboxy-
Cambridge id 5153935
Oprea1_020498
SCHEMBL71335
3.4-Pyridinedicarboxylic acid
3,4-pyridine dicarboxylic acid
3,4-pyridine-dicarboxylic acid
CHEMBL261326
NSC178
pyridine 3,4-dicarboxylic acid
BDBM26117
2,3-Pyridinedicarboxylic acid #
CS-D1674
Pyridin-3,4-dicarbonsA currencyure
STR01772
BBL010076
CL0113
STK801438
3,4-Pyridinedicarboxylic acid, 97%
AKOS000280879
AC-1183
FG-0458
BP-21355
SY004289
DB-028271
NS00043427
P0682
EN300-69982
AC-907/25014158
Q27120712
F0001-1280
Z1123696308