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Pyridine-3,5-dicarboxylic acid

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Identification
Molecular formula
C7H5NO4
CAS number
499-83-2
IUPAC name
pyridine-3,5-dicarboxylic acid
State
State

At room temperature, Pyridine-3,5-dicarboxylic acid is in a solid state, characterized by typical properties of solid aromatic compounds.

Melting point (Celsius)
247.00
Melting point (Kelvin)
520.15
Boiling point (Celsius)
0.00
Boiling point (Kelvin)
0.00
General information
Molecular weight
167.12g/mol
Molar mass
167.1220g/mol
Density
1.6030g/cm3
Appearence

Pyridine-3,5-dicarboxylic acid appears as a white crystalline solid. It is typically available in powder form and exhibits typical properties of aromatic carboxylic acids, including high solubility in polar solvents.

Comment on solubility

Solubility of Pyridine-3,5-Dicarboxylic Acid

Pyridine-3,5-dicarboxylic acid, with its chemical formula C7H7NO4, exhibits interesting solubility properties that are worth noting.

General Solubility

This compound is known to be soluble in water due to the presence of its carboxylic acid functional groups, which can engage in strong hydrogen bonding with water molecules. The solubility characteristics can be summarized as follows:

  • Good solubility in polar solvents such as water.
  • Moderate solubility in organic solvents like methanol and ethanol.
  • Poor solubility in non-polar solvents such as hexane or diethyl ether.

Factors Affecting Solubility

Several factors influence the solubility of pyridine-3,5-dicarboxylic acid:

  • Hydrogen Bonding: The ability to form hydrogen bonds enhances its solubility in polar environments.
  • pH of the Solution: In acidic or neutral conditions, the carboxylic acid groups remain protonated, whereas in basic conditions they can deprotonate, potentially increasing solubility.
  • Temperature: Increased temperature typically improves solubility, enabling greater dissolution of the compound.

In summary, the solubility profile of pyridine-3,5-dicarboxylic acid makes it a versatile compound in various chemical applications, especially in aqueous environments. As a quote goes, *"The solubility of a compound often dictates its utility in different chemical contexts."* This compound serves as an excellent example of how chemical structure can determine solubility behavior.

Interesting facts

Interesting Facts about Pyridine-3,5-Dicarboxylic Acid

Pyridine-3,5-dicarboxylic acid, commonly known as quinaldic acid, is an organic compound that plays a significant role in various chemical and biological processes. Here are some fascinating details about this compound:

  • Structural Features: The compound features a pyridine ring with two carboxylic acid functional groups positioned at the 3 and 5 carbon atoms. This unique arrangement contributes to its reactivity and its ability to form a variety of derivatives.
  • Versatile Applications: Pyridine-3,5-dicarboxylic acid is employed in several fields, including pharmaceuticals, agriculture, and dyes. Its derivatives are known to exhibit antibacterial and antifungal properties, making them useful in medicinal chemistry.
  • Biological Importance: The compound is involved in various biochemical pathways. Notably, its derivatives can act as chelating agents, allowing them to bind metal ions and influence enzymatic activities in biological systems.
  • Potential for Synthesis: Due to its functional groups, pyridine-3,5-dicarboxylic acid can serve as a building block in organic synthesis. It is particularly valued for creating complex molecules in organic reactions.
  • Environmental Considerations: As a product of certain natural processes, this compound can also be found in some natural sources. Its behavior in the environment is of interest from both ecological and toxicological perspectives.

In conclusion, pyridine-3,5-dicarboxylic acid stands out due to its unique structure and functional versatility, with applications that extend across various scientific disciplines. As researchers continue to explore its properties and potential, its significance in chemistry cannot be overstated.

Synonyms
Pyridine-3,5-dicarboxylic acid
3,5-Pyridinedicarboxylic acid
499-81-0
DINICOTINIC ACID
5-Carboxynicotinic acid
N5NMH4PZ3D
NSC-6497
CHEBI:46875
NSC 6497
EINECS 207-893-8
AI3-52669
DTXSID10198149
DTXCID90120640
207-893-8
MFCD00006393
NSC6497
Dinicotinic Acid; 3,5-Pyridinedicarboxylate; 5-Carboxynicotinic Acid; NSC 6497;
5-carboxy nicotinic acid
pyridine carboxylate, 6f
UNII-N5NMH4PZ3D
pyridine, 3,5-dicarboxy-
NCIStruc1_000161
NCIStruc2_000049
TimTec1_000362
Oprea1_413127
SCHEMBL51830
Pyridine-3,5-dicarboxylicacid
CHEMBL446761
BDBM26118
NCI6497
HMS1535A10
CCG-37624
NCGC00013071
STK301573
3,5-Pyridinedicarboxylic acid, 98%
AKOS000277471
AC-2844
CS-W002000
FG-0462
HY-W002000
NCGC00013071-02
NCGC00013071-03
NCGC00096195-01
BP-12521
NCI60_017340
SY003098
DB-022121
NS00043069
P0551
EN300-42792
Dinicotinic acid-3,5-pyridinedicarboxylic acid
AB00376196-04
SR-01000640386-1
Q15632703
Z275127642
3,5-Pyridinedicarboxylic acid, Vetec(TM) reagent grade, 98%