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4-Pyridinecarboxaldehyde oxime

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Identification
Molecular formula
C6H6N2O
CAS number
874-88-0
IUPAC name
pyridine-4-carbaldehyde oxime
State
State

At room temperature, 4-Pyridinecarboxaldehyde oxime is in a solid state, typically appearing as a crystalline powder.

Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
244.50
Boiling point (Kelvin)
517.65
General information
Molecular weight
122.13g/mol
Molar mass
122.1290g/mol
Density
1.0550g/cm3
Appearence

4-Pyridinecarboxaldehyde oxime is typically a white to off-white crystalline solid.

Comment on solubility

Solubility of Pyridine-4-carbaldehyde Oxime

Pyridine-4-carbaldehyde oxime is a compound with intriguing solubility characteristics. Understanding its solubility is crucial for various applications in chemical synthesis and research. Here are some key points to consider:

  • Polarity: Due to the presence of the oxime functional group and the nitrogen atom in its pyridine ring, pyridine-4-carbaldehyde oxime exhibits moderate polarity. This characteristic enhances its solubility in polar solvents.
  • Solvent Compatibility: It dissolves well in solvents such as:
    • Water
    • Ethanol
    • DMSO (Dimethyl sulfoxide)
    • Acetonitrile
  • Limited Solubility: However, it may have limited solubility in nonpolar solvents like hexane and toluene. This is likely due to its polar functional groups which do not interact favorably with nonpolar substances.
  • Temperature Effects: The solubility can also be influenced by temperature; typically, increasing the temperature enhances solubility in many cases, which can be particularly useful during recrystallization processes.

In summary, pyridine-4-carbaldehyde oxime is soluble in a range of polar solvents, which makes it versatile for various chemical processes. As with many compounds, understanding these solubility traits is essential for effective application in both laboratory settings and industrial uses.

Interesting facts

Interesting Facts About Pyridine-4-carbaldehyde Oxime

Pyridine-4-carbaldehyde oxime, also known by its IUPAC name 4-pyridinecarbaldehyde oxime, is a fascinating compound with a range of applications and interesting properties. Here are some key points to consider:

  • Versatile Intermediate: This compound serves as an important intermediate in the synthesis of various pharmaceuticals, agrochemicals, and dyes, driving innovation in multiple chemical sectors.
  • Chemical Reactivity: Its oxime functional group allows for intriguing chemical behavior; it can engage in various reactions such as rearrangements and condensation, making it a valuable participant in organic synthesis.
  • Biological Activity: Research shows that pyridine derivatives often exhibit biological activities. Pyridine-4-carbaldehyde oxime has drawn interest for potential roles in medicinal chemistry, particularly in the development of compounds with antimicrobial or anti-inflammatory properties.
  • Analytical Applications: Due to its distinctive structure, this compound is used in analytical chemistry for the detection and quantification of specific metal ions, showcasing its utility beyond organic synthesis.
  • Environmental Significance: Compounds containing pyridine rings are part of many natural products. Understanding their synthetic pathways can provide insights into environmental chemistry and the impact of nitrogen-containing compounds.

In the words of a prominent chemist, "The beauty of organic chemistry lies in the interplay of structure and function, transforming simple molecules into complex intermediates with vast potential." Pyridine-4-carbaldehyde oxime exemplifies this principle through its diverse applications and remarkable chemical capabilities.

As a student of chemistry, exploring compounds like pyridine-4-carbaldehyde oxime can unlock new ways of thinking about synthesis, reactivity, and application in real-world scenarios. Its presence in both academic research and industry underscores the importance of studying such intriguing compounds.

Synonyms
4-Pyridinecarbaldehyde oxime
N-(pyridin-4-ylmethylidene)hydroxylamine
4-Pyridinaldoxime
N-[(pyridin-4-yl)methylidene]hydroxylamine
pyridine-4-carbaldoxime
NCIOpen2_000053
4-Pyridinecarboxaldehyde Oxime
SCHEMBL352177
OFYLBLSSPQTTHT-UHFFFAOYSA-N
XFNAGAQPPRZSFP-UHFFFAOYSA-N
ALBB-019921
AKOS000266529
AKOS015935085
SY047590
DB-055314
P0673
(Z)-N-(PYRIDIN-4-YLMETHYLIDENE)HYDROXYLAMINE