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Isonicotinic acid hydrazide

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Identification
Molecular formula
C6H7N3O
CAS number
54-85-3
IUPAC name
pyridine-4-carbohydrazide;1-tetrahydrofuran-2-ylethanone
State
State

At room temperature, isonicotinic acid hydrazide is a solid.

Melting point (Celsius)
171.00
Melting point (Kelvin)
444.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
137.14g/mol
Molar mass
137.1410g/mol
Density
1.5900g/cm3
Appearence

Isonicotinic acid hydrazide, commonly known as isoniazid, appears as a white to slightly yellow crystalline powder.

Comment on solubility

Solubility Characteristics of Pyridine-4-Carbohydrazide; 1-Tetrahydrofuran-2-ylethanone

Pyridine-4-carbohydrazide; 1-tetrahydrofuran-2-ylethanone is an intriguing compound with notable solubility traits. Understanding its solubility is crucial for applications in both synthesis and pharmaceutical formulations. Here are some key points regarding its solubility:

  • Polar vs. Non-Polar Environments: The compound contains both polar and non-polar groups, which contributes to its solubility in a range of solvents.
  • Solvent Compatibility: It tends to be soluble in polar organic solvents such as methanol, ethanol, and dichloromethane, while exhibiting variable solubility in non-polar solvents.
  • Hydrogen Bonding: Due to the presence of hydrazide and pyridine functionalities, strong hydrogen bonding capabilities can enhance solubility in polar solvents.
  • Effect of Temperature: Increasing temperature generally improves solubility for many organic compounds, including this one, allowing for greater dissolution in solvents.

In summary, the solubility of pyridine-4-carbohydrazide; 1-tetrahydrofuran-2-ylethanone is influenced by several factors such as solvent type, temperature, and the structural features of the compound itself. Its compatible solubility profile makes it a versatile candidate for various chemical applications.

Interesting facts

Pyridine-4-carbohydrazide; 1-tetrahydrofuran-2-ylethanone

Pyridine-4-carbohydrazide; 1-tetrahydrofuran-2-ylethanone is a fascinating compound that finds various applications in both organic synthesis and medicinal chemistry. Here are some interesting facts about this intriguing substance:

  • Versatile Building Block: This compound acts as a versatile intermediate in the synthesis of a variety of pharmaceuticals and agrochemicals.
  • Biological Relevance: The presence of the pyridine moiety often contributes to biological activity, making it a subject of interest for drug design and development.
  • Reactivity: Pyridine derivatives have unique electrophilic and nucleophilic properties, allowing them to participate in numerous chemical reactions such as electrophilic aromatic substitution and nucleophilic addition.
  • Sustainability Aspect: The incorporation of tetrahydrofuran into its structure suggests potential pathways for green chemistry, where safer solvents are used in chemical reactions.
  • Research Interest: The compound's structure has made it a topic of various research studies aimed at exploring its therapeutic potentials, particularly in combating diseases.
  • Complexity and Challenge: The synthesis and purification of this compound can be challenging due to its complex structure, often providing a stimulating challenge for chemists.

In summary, Pyridine-4-carbohydrazide; 1-tetrahydrofuran-2-ylethanone not only serves as an essential chemical compound but also opens avenues for research and application in fields such as medicinal chemistry, organic synthesis, and environmental studies. With ongoing research, we may unveil more of its potential benefits in various industrial and biological contexts.