Pyrrolidinium chloride | Solubility of Things

Identification

Molecular formula

C₄H₁₀ClN₂

CAS number

6100-05-6

IUPAC name

pyrrolidin-1-ium-1-amine;chloride

State

At room temperature, pyrrolidinium chloride is typically in a solid state. It is commonly presented as a crystalline solid.

Melting point (Celsius)

140.00

Melting point (Kelvin)

413.15

Boiling point (Celsius)

199.10

Boiling point (Kelvin)

472.25

General information

Molecular weight

104.59g/mol

Molar mass

104.5850g/mol

Density

0.9998g/cm³

Appearence

Pyrrolidinium chloride is typically a white to off-white crystalline solid. It may occasionally be found as a powder. Its appearance can vary slightly depending on the specific form and method of synthesis.

Comment on solubility

Solubility of Pyrrolidin-1-ium-1-amine Chloride

Pyrrolidin-1-ium-1-amine chloride, a quaternary ammonium compound, exhibits a profound affinity for solubility in various solvents. Its solubility characteristics can be summarized as follows:

Aqueous Solubility: This compound is typically soluble in water, owing to the presence of the pyrrolidin-1-ium cation which enhances its hydrophilicity.
Polar Solvents: In addition to water, pyrrolidin-1-ium-1-amine chloride is likely to be soluble in other polar solvents such as methanol and ethanol, since these solvents can also stabilize the ionic interactions.
Non-Polar Solvents: It should be noted that solubility in non-polar solvents is considerably limited due to the ionic nature of the compound.

It's important to consider factors such as temperature, as solubility often increases with rising temperature due to the enhanced kinetic activity of molecules, facilitating interactions with solvent molecules. As water solubility plays a critical role in many biological and chemical processes, the solubility of pyrrolidin-1-ium-1-amine chloride can significantly impact its function in various applications.

Interesting facts

Interesting Facts about Pyrrolidin-1-ium-1-amine Chloride

Pyrrolidin-1-ium-1-amine chloride is a fascinating compound that has gained attention in various scientific fields, especially in organic chemistry and pharmacology. Here are some noteworthy aspects of this compound:

Structure and Stability: The compound features a pyrrolidine ring that is positively charged due to the ammonium group. This unique structure contributes to its stability and its reactivity in different chemical reactions.
Biological Relevance: Pyrrolidine derivatives, such as this compound, are of particular interest in medicinal chemistry due to their potential bioactivity. They are often investigated for their role in various therapeutic areas, including neuropharmacology.
Applications: Pyrrolidin-1-ium-1-amine chloride is used as an important intermediate in the synthesis of fine chemicals and agrochemicals. Its derivatives may act as catalysts or reagents in various chemical transformations.
Charge and Solubility: The chloride ion associated with the pyrrolidin-1-ium-1-amine contributes to its solubility in water, making it useful in solutions where ionic compounds are required.
Research Insights: Studies involving this compound often explore its interaction with biological membranes or its transport mechanisms, providing insights into how such molecules can influence cellular processes.

As quoted by researchers in the field, *“Understanding the properties and applications of pyrrolidine derivatives opens new avenues in drug development and organic synthesis.”* This indicates the broader importance of studying such compounds.

In summary, pyrrolidin-1-ium-1-amine chloride exemplifies the diversity and functionality of nitrogen-containing heterocycles in chemistry. Its study not only furthers our understanding of chemical reactivity but also its application in real-world scenarios, making it a compound worth exploring in greater depth.