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6-aminoquinoline

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Identification
Molecular formula
C9H8N2
CAS number
580-17-6
IUPAC name
quinolin-6-amine
State
State

At room temperature, 6-aminoquinoline is in a solid state. It typically manifests as a crystalline powder, characteristic of many organic compounds. Its solid state is stable under normal conditions, making it manageable for various applications and reactions in a laboratory setting.

Melting point (Celsius)
187.00
Melting point (Kelvin)
460.15
Boiling point (Celsius)
308.90
Boiling point (Kelvin)
582.05
General information
Molecular weight
144.18g/mol
Molar mass
144.1840g/mol
Density
1.2005g/cm3
Appearence

6-Aminoquinoline appears as a yellow crystalline solid. It is often utilized in the preparation of chemicals, particularly in creating compounds that are used in pharmaceuticals. The crystalline form is easily recognizable by its distinctive color, which provides a useful visual cue for identification during laboratory processes.

Comment on solubility

Solubility of Quinolin-6-amine

Quinolin-6-amine, with the chemical formula C9H8N2, exhibits interesting solubility characteristics. As an organic compound that belongs to the class of aminoquinolines, its solubility in various solvents can be significantly influenced by several factors:

  • Polarity: Quinolin-6-amine is moderately polar due to the presence of the amino group. This property generally allows it to dissolve better in polar solvents.
  • Solvents: It is soluble in water, methanol, and ethanol, which are polar solvents, while showing limited solubility in non-polar solvents such as hexane or benzene.
  • Temperature: The solubility may increase with temperature, suggesting that heating the solvent could enhance the dissolution process.

In practical applications, the solubility profile of quinolin-6-amine is essential for its use in various chemical syntheses and pharmaceutical formulations. The following points help summarize its solubility behavior:

  1. Moderate solubility in polar solvents.
  2. Limited solubility in non-polar solvents.
  3. Increased solubility with rising temperature.

Understanding these solubility traits is crucial for effectively utilizing quinolin-6-amine in both laboratory and industrial settings.

Interesting facts

Interesting Facts about Quinolin-6-amine

Quinolin-6-amine is an intriguing compound that holds a significant place in the realm of organic chemistry and medicinal applications. Here are some interesting points about this unique chemical:

  • Structural Significance: Quinolin-6-amine belongs to the class of aminoquinolines, which are derived from quinoline, a bicyclic compound known for its aromatic properties. The amine group at the 6-position adds to its reactivity and functional versatility.
  • Biological Relevance: This compound has garnered interest in the field of pharmaceuticals due to its potential as a building block for various biologically active molecules. Its derivatives are explored for their anticancer, antimicrobial, and antiviral properties.
  • Synthesis Approach: Chemists can synthesize quinolin-6-amine through diverse methods, including the reduction of corresponding nitro or nitrile derivatives. This flexibility is appealing for developing customized compounds for specific applications.
  • Research Applications: Research studies have highlighted quinolin-6-amine and its derivatives in medicinal chemistry research, particularly in developing drugs targeting diseases such as malaria and other tropical diseases.
  • Potential in Luminescent Materials: There is ongoing exploration of quinolin-6-amine in the development of luminescent materials, making it an exciting candidate for applications in organic light-emitting diodes (OLEDs) and organic photovoltaic cells.

In conclusion, quinolin-6-amine is more than just a simple amine; it is a compound with rich structural features and a wide array of applications in both basic and applied sciences. The ongoing research and developments surrounding this compound emphasize its importance in modern chemistry and potential future uses in various fields.

Synonyms
6-AMINOQUINOLINE
580-15-4
6-Quinolinamine
Quinoline, 6-amino-
Quinolin-6-ylamine
CCRIS 1681
EINECS 209-453-0
NSC 58388
DTXSID80206725
Quinoline, 6-amino-(8CI)
DTXCID10129216
rjsrsritmwviqt-uhfffaoysa-n
Quinolin-6-amine
MFCD00006803
MLS000080747
NSC-58388
SMR000036663
6-quinolylamine
6-amino quinoline
3kqp
quinoline-6-amine
6-Amino-quinoline
quinolin-6-yl amine
6-Aminoquinoline, 98%
(Ziprasidone Impurity B)
cid_11373
BIDD:GT0636
CHEMBL99408
SCHEMBL160217
XN7T264NL4
SCHEMBL12280915
BDBM32026
HMS2451C16
ALBB-014510
NSC58388
STK328120
AKOS000131287
AC-4708
CS-W007404
FA00884
HY-W007404
PS-4529
SB67524
SY021131
DB-031615
A1370
NS00033833
EN300-41836
US8546389, 98
AC-907/25014243
Q27460051
F2190-0533
Z255114686