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Quinoline-2-carbaldehyde oxime

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Identification
Molecular formula
C10H8N2O
CAS number
125562-39-0
IUPAC name
quinoline-2-carbaldehyde oxime
State
State
At room temperature, quinoline-2-carbaldehyde oxime is a solid. Its stability at this state makes it suitable for storage and handling in various chemical processes. The crystalline form enhances its shelf life and consistency for research purposes.
Melting point (Celsius)
172.00
Melting point (Kelvin)
445.20
Boiling point (Celsius)
337.30
Boiling point (Kelvin)
610.50
General information
Molecular weight
172.19g/mol
Molar mass
172.1920g/mol
Density
1.1510g/cm3
Appearence
Quinoline-2-carbaldehyde oxime appears as a white to light yellow crystalline solid. Its crystalline nature and coloration suggest purity and its distinct structure is visible under microscopic analysis. The compound is often used for analytical and synthetic applications due to its stability in solid form.
Comment on solubility

Solubility of Quinoline-2-carbaldehyde Oxime

Quinoline-2-carbaldehyde oxime, a compound derived from the heterocyclic structure of quinoline, exhibits noteworthy solubility characteristics that can be influenced by various factors:

  • Solvent Interactions: This compound is typically soluble in organic solvents such as ethanol and dimethyl sulfoxide (DMSO). Its solubility in polar solvents can be attributed to the presence of the oxime functional group, which facilitates hydrogen bonding.
  • Water Solubility: Interestingly, quinoline derivatives generally demonstrate poor solubility in water due to their aromatic structure and hydrophobic nature. Thus, quinoline-2-carbaldehyde oxime may also show limited water solubility.
  • Temperature Dependence: As with many organic compounds, temperature plays a crucial role in solubility. An increase in temperature can enhance solubility in certain solvents, making the compound more amenable to dissolution.

In summary, the solubility of quinoline-2-carbaldehyde oxime is largely dictated by the choice of solvent, temperature, and the specific interactions occurring at a molecular level. Understanding these variables is essential for effectively utilizing this compound in various applications.

Interesting facts

Interesting Facts about Quinoline-2-carbaldehyde Oxime

Quinoline-2-carbaldehyde oxime is a fascinating compound that draws interest from both organic chemists and those studying medicinal chemistry. It belongs to the class of oximes, which are compounds formed from aldehydes or ketones through a reaction with hydroxylamine. Here are some intriguing insights about this unique substance:

  • Structure and Characteristics: The structure of quinoline-2-carbaldehyde oxime incorporates both a quinoline ring system and an oxime functional group, making it an interesting target for synthetic modifications.
  • Reactivity: The oxime functional group can behave as a versatile site for further chemical reactions, such as cyclization, which can lead to the formation of various nitrogen-containing heterocycles.
  • Pharmacological Potential: Compounds related to quinoline have shown significant biological activities, such as antimicrobial and antimalarial properties. Quinoline-2-carbaldehyde oxime is being investigated for similar potential, particularly in drug design.
  • Significance in Research: This compound serves as an important intermediate in the synthesis of other complex molecules, expanding its utility in organic synthesis.
  • Applications in Analytical Chemistry: The flexibility of the oxime group makes quinoline-2-carbaldehyde oxime useful in analytical techniques, particularly in the determination of metal ions through complexation reactions.

Overall, quinoline-2-carbaldehyde oxime demonstrates the diverse functionality and potential applications of oxime derivatives in various fields, such as medicinal chemistry and material science. The convergence of its unique structural features and utility underscores the ongoing interest it garners within the scientific community.

Synonyms
quinolylnitrone
NCIOpen2_001190
Oprea1_833163
SCHEMBL2161944
SCHEMBL26608174
DTXSID101302553
HMS2803F16
AKOS017514112
DB-231730
NS00045331