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Quinoline-2-thiol

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Identification
Molecular formula
C9H7NS
CAS number
95-54-5
IUPAC name
quinoline-2-thiol
State
State

At room temperature, quinoline-2-thiol is in a solid state. The compound is usually stable when stored in a well-sealed container in a cool, dry place.

Melting point (Celsius)
48.00
Melting point (Kelvin)
321.15
Boiling point (Celsius)
290.00
Boiling point (Kelvin)
563.15
General information
Molecular weight
161.23g/mol
Molar mass
161.2320g/mol
Density
1.2490g/cm3
Appearence

Quinoline-2-thiol typically appears as a yellow to brown crystalline solid. It is known for its distinct and characteristic odor, which is often slightly unpleasant.

Comment on solubility

Solubility of Quinoline-2-thiol

Quinoline-2-thiol is an organic compound with unique structural features that significantly influence its solubility characteristics. The presence of the thiol (-SH) group coupled with the quinoline ring structure plays a crucial role in how this compound interacts with various solvents.

Solubility in Different Solvents

Here’s how quinoline-2-thiol typically behaves in certain environments:

  • Water: Quinoline-2-thiol has limited solubility in water due to the hydrophobic nature of the quinoline ring, although the thiol group can form hydrogen bonds, offering some degree of interaction.
  • Organic Solvents: This compound demonstrates good solubility in many organic solvents. Common solvents include:
    • Ethanol
    • Acetone
    • Dimethyl sulfoxide (DMSO)

According to chemists, "the solubility profile of quinoline-2-thiol is predominantly governed by its molecular interactions with solvents, particularly in non-polar and polar protic environments." Therefore, it can be stated that:

  • Its solubility is favored in polar organic solvents.
  • It tends to be poorly soluble in water, highlighting the importance of solvent choice in experimental applications.

Understanding the solubility of quinoline-2-thiol is essential for its applications in research and industry, where solvent compatibility can affect reactions and product formulations.

Interesting facts

Interesting Facts About Quinoline-2-thiol

Quinoline-2-thiol is a fascinating compound with a variety of applications in both research and industry. As a member of the quinoline family, this compound features a unique structure that contributes to its interesting properties. Here are some noteworthy aspects of quinoline-2-thiol:

  • Biological Importance: Quinoline-2-thiol is well-known for its biological activity, often serving as a core structure in the development of pharmaceutical agents. Its derivatives have been studied for their potential antibacterial and antifungal properties.
  • Coordination Chemistry: This compound possesses a thiol functional group, which enhances its ability to form stable complexes with metal ions. As such, it plays a crucial role in coordination chemistry, particularly in the formation of metal-thiol complexes.
  • Synthetic Utility: Quinoline-2-thiol is a valuable building block in organic synthesis. It can participate in a variety of chemical reactions, such as electrophilic substitutions and nucleophilic attacks, making it an essential tool in the lab.
  • Fluorescent Properties: Some studies have indicated that quinoline-2-thiol exhibits fluorescence under certain conditions. This property makes it useful in various analytical applications, particularly in the detection of metal ions.
  • Environmental Relevance: Quinoline derivatives, including quinoline-2-thiol, can be involved in environmental remediation strategies. They may be used in the extraction and removal of heavy metals from contaminated environments.

In summary, quinoline-2-thiol is not just a simple compound; its wide range of applications and interesting reactivity make it a noteworthy subject for scientists and students alike. As one chemist aptly put it, “The beauty of chemistry lies in the unexpected connections that compounds can reveal.”