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Quinidine sulfate

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Identification
Molecular formula
(C20H24N2O2)2•H2SO4
CAS number
50-54-4
IUPAC name
(R)-(6-methoxy-4-quinolyl)-[(2S,5R)-5-vinylquinuclidin-2-yl]methanol;sulfuric acid
State
State

At room temperature, quinidine sulfate is typically in a solid state, appearing as crystalline powder.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
225.00
Boiling point (Kelvin)
498.15
General information
Molecular weight
782.97g/mol
Molar mass
782.9680g/mol
Density
1.2600g/cm3
Appearence

Quinidine sulfate appears as a white, odorless, crystalline powder. It is known for its bitter taste and is slightly hygroscopic.

Comment on solubility

Solubility of (R)-(6-methoxy-4-quinolyl)-[(2S,5R)-5-vinylquinuclidin-2-yl]methanol; sulfuric acid

The solubility of (R)-(6-methoxy-4-quinolyl)-[(2S,5R)-5-vinylquinuclidin-2-yl]methanol in sulfuric acid is quite intriguing and can be discussed through several key points:

  • Nature of the Compound: This compound features both hydrophilic and hydrophobic characteristics due to its complex organic structure, which impacts its solubility.
  • Solvent Interaction: Sulfuric acid, being a strong acid and polar solvent, can facilitate the dissolution of the compound through protonation and solvation effects.
  • Concentration Dependence: The solubility might vary with the concentration of sulfuric acid. For instance, increased acidity can enhance solubility due to better interaction of functional groups in the compound.
  • Temperature Effects: As is common with many organic compounds, increased temperature likely improves solubility by promoting molecular motion and breaking intermolecular forces.

In summary, the solubility of (R)-(6-methoxy-4-quinolyl)-[(2S,5R)-5-vinylquinuclidin-2-yl]methanol in sulfuric acid results from a combination of its unique molecular characteristics and the solvent's properties. While comprehensive experimental data would provide the most accurate insight, factors such as polarity, molecular interactions, and environmental conditions play crucial roles in influencing solubility.

Interesting facts

Interesting Facts about (R)-(6-methoxy-4-quinolyl)-[(2S,5R)-5-vinylquinuclidin-2-yl]methanol; sulfuric acid

This compound, with a fascinating structural complexity, serves a significant role in various fields of chemistry and pharmacology. One of the most intriguing aspects of this compound is its chiral nature, where the (R) configuration provides it with unique properties that are often crucial in biological interactions. Chirality is essential in drug design, as different enantiomers can exhibit vastly different pharmacological effects.

Key Highlights:

  • Quinoline Derivative: The inclusion of a quinoline moiety enriches its potential applications, particularly in developing anti-microbial and anti-inflammatory agents.
  • Quinuclidine Structure: The quinuclidine scaffold is well-known in medicinal chemistry for its role in enhancing bioactivity, making compounds more effective as therapeutics.
  • Versatile Reactions: This compound can participate in various chemical reactions, providing pathways for further molecular modifications that could yield new derivatives with enhanced properties.
  • Aromatic Behavior: The methoxy group on the aromatic ring contributes to its electronic properties, affecting both its reactivity and interaction with biological targets.

Moreover, when combined with sulfuric acid, this compound may undergo protonation, leading to new opportunities for synthesis and reactivity. The interplay between different functional groups within such a complex molecule opens the door to a myriad of potential applications, especially in fine organic synthesis and drug development.

In summary, the (R)-(6-methoxy-4-quinolyl)-[(2S,5R)-5-vinylquinuclidin-2-yl]methanol; sulfuric acid compound illustrates the beauty of molecular design, where every atom plays a significant role in its chemical behavior, biological efficacy, and potential therapeutic benefits.

Synonyms
SCHEMBL21293794
RONWGALEIBILOG-PLYVKUMQSA-N
HMS3263M19
CCG-222333
LP01029
EU-0101029
F81522
Q 1250