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Dipalmitoylphosphatidylethanolamine

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Identification
Molecular formula
C41H82N1O8P1
CAS number
5816-40-8
IUPAC name
S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadecanethioate
State
State

At room temperature, dipalmitoylphosphatidylethanolamine is a solid compound.

Melting point (Celsius)
121.00
Melting point (Kelvin)
394.15
Boiling point (Celsius)
180.00
Boiling point (Kelvin)
453.15
General information
Molecular weight
743.08g/mol
Molar mass
743.0830g/mol
Density
1.0000g/cm3
Appearence

Dipalmitoylphosphatidylethanolamine typically appears as a white or off-white powder. It is often used in the formation of liposomes due to its biocompatible properties.

Comment on solubility

Solubility of S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadecanethioate (C41H82N1O8P1)

The solubility of this complex compound can be quite intriguing, given its extensive molecular structure. Here are several key points to consider:

  • Hydrophobic Regions: The presence of a long hydrocarbon chain (octadecanethioate) imparts significant hydrophobic characteristics, often leading to lower solubility in water.
  • Hydrophilic Functional Groups: The compound's structure includes multiple phosphate and hydroxyl groups, which can enhance solubility in aqueous environments, particularly in polar solvents.
  • Influence of pH: The solubility may vary depending on pH levels due to ionization of the ammonium and phosphate groups, affecting their solvation in water.
  • Temperature Effects: Generally, increased temperature may improve solubility for many compounds, which could be applicable here depending on the interactions at play.

In conclusion, the overall solubility of S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadecanethioate is likely to exhibit a complex equilibrium between hydrophilic and hydrophobic interactions, which ultimately determines its behavior in various solvent systems.

Interesting facts

Interesting Facts about S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadecanethioate

This compound is a fascinating example of complex organic chemistry, showcasing the intersection of nucleic acids, phosphates, and lipids. Here are some intriguing insights:

  • Biological Relevance: This compound plays a significant role in biological systems, particularly in the context of nucleotide analogs and their applications in drug design and molecular biology.
  • Structure Complexity: With a lengthy name and diverse functional groups, the compound includes elements such as amino groups, phosphonates, and sugar-derived entities, demonstrating the intricate design found in biomolecules.
  • Phosphorylation: The presence of multiple phosphoryl groups indicates its potential in signaling pathways and energy transfer, reminiscent of important biomolecules like ATP.
  • Drug Development: Due to its complex structure, this compound could serve as a template for developing new medicinal agents, particularly those targeting specific cellular pathways or activities.
  • Solubility Challenges: The numerous hydrophilic and lipophilic components may influence the solubility profile, making it an interesting subject for formulation studies.

As noted by chemist Richard Feynman, “What I cannot create, I do not understand.” This aphorism captures the adventurous spirit of synthetic chemistry, where understanding such complex compounds is essential to innovating and creating new therapeutic modalities.

The study of compounds like S-[2-[3-[[4-[[[5-(6-aminopurin-9-yl)-4-hydroxy-3-phosphonooxy-tetrahydrofuran-2-yl]methoxy-hydroxy-phosphoryl]oxy-hydroxy-phosphoryl]oxy-2-hydroxy-3,3-dimethyl-butanoyl]amino]propanoylamino]ethyl] octadecanethioate opens doors to deeper knowledge in the fields of biochemistry and medicinal chemistry, exhibiting the beauty of molecular design and function.

Synonyms
Stearoyl coenzyme A
Octadecanoyl coenzyme A
Stearoyl coenzyme A free acid
HY-165814