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Carbimazole

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Identification
Molecular formula
C12H19ClN2OS
CAS number
22232-54-8
IUPAC name
S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate;hydrochloride
State
State

Solid: At room temperature, carbimazole exists as a solid. It is typically handled as a powder in pharmaceutical applications.

Melting point (Celsius)
90.00
Melting point (Kelvin)
363.15
Boiling point (Celsius)
250.00
Boiling point (Kelvin)
523.15
General information
Molecular weight
277.38g/mol
Molar mass
277.3820g/mol
Density
1.3000g/cm3
Appearence

Carbimazole is a white to pale yellow crystalline powder. Its appearance is crucial for identification and purity assessment.

Comment on solubility

Solubility of S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate; hydrochloride

The solubility of S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate; hydrochloride (C12H19ClN2OS) can be influenced by several key factors, which are essential to understand when working with this compound.

Factors Affecting Solubility:

  • Polarity: The presence of the hydrochloride group often enhances solubility in polar solvents like water, due to ionic interactions.
  • Temperature: Higher temperatures can generally increase solubility, encouraging more dissolution in solvents.
  • pH Levels: The solubility of this compound may vary with different pH levels, as the ionization of functional groups is influenced by the acidity or basicity of the solution.

In practical terms, it is suggested that:

  1. The compound is more soluble in aqueous acidic solutions compared to basic environments.
  2. It may demonstrate limited solubility in non-polar solvents, owing to its complex structure and ionic character.

Understanding these solubility traits can be pivotal in applications such as pharmaceuticals, where solubility often dictates biological availability. In summary, the solubility behavior of S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate; hydrochloride is marked by its ionic nature and solvent interactions, making it crucial for researchers to assess conditions carefully for optimal use.

Interesting facts

Interesting Facts about S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate;hydrochloride

S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate;hydrochloride is a fascinating compound that belongs to the class of carbamate derivatives. Here are some intriguing insights regarding this compound:

  • Applications in Pharmaceuticals: This compound has potential applications in the pharmaceutical industry. Its structure allows it to interact with various biological targets, potentially leading to the development of new therapeutic agents.

  • Mechanism of Action: As a carbamate derivative, it may act as an inhibitor of certain enzymes, leading to effects on neurotransmitter levels. This characteristic is crucial for its role in medicinal applications.

  • Structural Features: The presence of the diethylamino group enhances solubility in biological systems, while the diphenyl structure may enhance binding affinity to target molecules, making it a versatile compound in drug design.

  • Safety Considerations: As with many synthetic compounds, it is essential to consider the pharmacological safety profile, focusing on possible toxicity and side effects when considering this compound for therapeutic use.

  • Research Significance: Compounds like this one play a critical role in the exploration of new chemical therapies and can be vital in medicinal chemistry and drug discovery processes.

Overall, S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate;hydrochloride serves as an exciting example of the intersection between compound structure and function, demonstrating how small variations in chemical architecture can lead to different biological activities.

Synonyms
Phencarbamide hydrochloride
Fencarbamide hydrochloride
58-13-9
Phenocarbamide hydrochloride
B77786C9A5
S-[2-(Diethylamino)ethyl] diphenyldithiocarbamate monohydrochloride
S-(2-(Diethylamino)ethyl) diphenyldithiocarbamate monohydrochloride
S-[2-(diethylamino)ethyl] N,N-diphenylcarbamothioate;hydrochloride
Fencarbamide HCl
Phencarbamid hydrochlorid [German]
EINECS 200-363-7
BA 1355
Phencarbamid hydrochlorid
Diphenylamin-(beta-diaethylaminoaethyl)carbamidthioester
SCHEMBL15453584
UNII-B77786C9A5
DTXSID40973567
QHTWTHGLTISQOF-UHFFFAOYSA-N
S-(2-(Diethylamino)ethyl) diphenylthiocarbamate hydrochloride
Diphenylamin-(beta-diaethylaminoaethyl)carbamidthioester [German]
Diphenylthiocarbamic acid S-(2-(diethylamino)ethyl) ester hydrochloride
Diphenylcarbamothioic acid S-(2-(diethylamino)ethyl) ester hydrochloride
BA-1355
CARBAMIC ACID, DIPHENYLTHIO-, S-(2-(DIETHYLAMINO)ETHYL) ESTER, HYDROCHLORIDE
PHENCARBAMIDE HYDROCHLORIDE [MI]
Q27274454
S-[2-(Diethylamino)ethyl] diphenylcarbamothioate--hydrogen chloride (1/1)
CARBAMOTHIOIC ACID, N,N-DIPHENYL-, S-(2-(DIETHYLAMINO)ETHYL) ESTER, HYDROCHLORIDE (1:1)