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Propofol

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Identification
Molecular formula
C12H18O
CAS number
2078-54-8
IUPAC name
S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate
State
State

At room temperature, propofol is in a liquid state, specifically as an emulsion for medical use.

Melting point (Celsius)
-58.00
Melting point (Kelvin)
215.15
Boiling point (Celsius)
308.00
Boiling point (Kelvin)
581.15
General information
Molecular weight
178.27g/mol
Molar mass
178.2700g/mol
Density
1.0210g/cm3
Appearence

Propofol is a white, oil-in-water emulsion with a milky appearance. In its pure form, it is a colorless oil. The emulsion form is specifically designed for intravenous administration.

Comment on solubility

Solubility of S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate

The solubility characteristics of S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate are influenced by its unique molecular structure. This compound, featuring a thioate functional group, along with dipropylamino side chains, exhibits notable behavior in various solvents.

General Solubility Insights:

  • Solvent Polarity: Due to its organic nature and hydrophobic components, this compound tends to have limited solubility in water but is more soluble in organic solvents such as ethanol, acetone, or chloroform.
  • Temperature Dependency: Like many chemical compounds, its solubility can be affected by temperature. Typically, increasing temperature can enhance solubility in organic solvents.
  • Interaction with Solvents: The presence of the dipropylamino group can lead to specific interactions with polar solvents, potentially leading to altered solubility profiles under varying conditions.

To summarize, while S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate shows limited aqueous solubility, it favors organic solvents, making it essential to consider the solvent choice in applications involving this compound. Such solubility behavior plays a critical role in its chemical reactivity and practicality in industrial uses.

Interesting facts

Interesting Facts about S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate

S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate is a fascinating compound that has garnered attention in various fields of chemistry and pharmacology. Here are some highlights:

  • Biological Activities: This compound has been studied for its potential biological activities. It shows promising results in terms of its interactions with specific receptors and enzymes in the body, which could lead to applications in drug development.
  • Synthetic Versatility: The synthesis of this compound often involves multi-step organic reactions, showcasing the versatility of modern synthetic techniques. The ability to create such complicated structures underlines the ingenuity of organic chemists.
  • Structure-Activity Relationship: The presence of the dipropylamino group in the structure allows for a better understanding of how modifications on the molecule can affect its biological efficacy. This is a crucial aspect in medicinal chemistry when designing new pharmaceuticals.
  • Applications in Research: Researchers are intrigued by how compounds like this one can serve as tools for studying various biological processes. Their unique chemical properties may lead to discoveries in pharmacology and toxicology.
  • Safety and Toxicity: As with many chemical compounds, understanding the safety profile of S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate is essential. Toxicological studies help ensure that this compound can be used safely in laboratory and clinical settings.

In the words of renowned chemist Robert H. Grubbs: "The most important aspect of science is questioning everything." This compound exemplifies that philosophy, offering a window into the complex world of organic chemistry and its potential to improve human health.

With ongoing research, the future of S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate will undoubtedly reveal more intriguing characteristics and applications in the scientific community.

Synonyms
Diprofene
Diprofenum
Diprofen
Diprofeno
Diprophen
5835-72-3
Diprofene [INN]
UNII-O99X77ZQ8E
O99X77ZQ8E
2-Dipropylaminoethyl diphenylthioacetate
S-2-Dipropylaminoethyl diphenylthioacetat
DTXSID40207076
Diphenylthioessigsaeure-S-(2-dipropylaminoehtyl)ester
DTXCID40129567
S-[2-(dipropylamino)ethyl] 2,2-diphenylethanethioate
SCHEMBL2110770
CHEMBL2104288
Q27285513