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Orphenadrine

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Identification
Molecular formula
C18H23NO
CAS number
83-98-7
IUPAC name
S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate
State
State
Orphenadrine exists as a solid at room temperature, typically in powder form.
Melting point (Celsius)
123.00
Melting point (Kelvin)
396.15
Boiling point (Celsius)
340.00
Boiling point (Kelvin)
613.15
General information
Molecular weight
265.37g/mol
Molar mass
265.3690g/mol
Density
1.0563g/cm3
Appearence

Orphenadrine is typically a white or almost white crystalline powder that is odorless and has a slightly bitter taste. It is commonly formulated into tablets or extended-release forms for medicinal purposes.

Comment on solubility

Solubility of S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate

The solubility of S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate can be characterized by several factors:

  • Polarity: Given its structure featuring a pyridine ring and a thioester group, the compound exhibits a certain degree of polarity, which affects its solubility in various solvents.
  • Solvent Compatibility: This compound is expected to be soluble in polar solvents, such as water and alcohols, due to the presence of functional groups that can engage in hydrogen bonding.
  • Temperature Dependence: The solubility may increase with temperature, which is common for many organic compounds, allowing for greater interaction with solvent molecules.
  • pH Sensitivity: The solubility can also be influenced by the pH of the solution, as ionization of the amino group can enhance its solubility in aqueous environments.

In summary, while the precise solubility of S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate in various solvents requires empirical testing, its structural features suggest a relatively good solubility in polar media under appropriate conditions. As always, it’s essential to consider specific conditions when assessing solubility.

Interesting facts

Interesting Facts about S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate

S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate is a compound that piques the interest of chemists and biochemists alike due to its unique structural attributes and potential applications.

1. Structural Characteristics

  • Aminomethyl Group: This functional group enhances the compound's biological activity and is often associated with increased reactivity.
  • Pyridine Ring: The inclusion of a pyridine ring contributes to the compound’s aromatic properties, making it a key player in many chemical reactions.
  • Thioate Functionality: The ethanethioate component introduces sulfur into the molecule, which can result in distinctive chemical behavior compared to oxygen-containing analogs.

2. Biological Relevance

This compound may serve as an important precursor or intermediate in the synthesis of pharmaceuticals:

  • Potential Medicinal Uses: The intricate structure suggests that it might play a role in developing drugs targeting various biological pathways.
  • Research in Enzyme Inhibition: Compounds like this are often studied for their inhibitory effects on certain enzymes, adding to their impact in medicinal chemistry.

3. Chemical Behavior

Given its unique combination of functional groups, S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate exhibits interesting chemical behavior:

  • Reactivity: The thiol group may engage in nucleophilic attacks, potentially leading to novel synthetic pathways.
  • Stability Concerns: The presence of multiple functional groups could affect the compound’s stability under varying conditions, making it a subject of study in reaction kinetics.

In summary, the complex architecture of S-[[4-(aminomethyl)-5-hydroxy-6-methyl-3-pyridyl]methyl] ethanethioate not only enhances its reactivity but also propels it into the spotlight for potential medicinal applications. This compound exemplifies the continuous allure of organic synthesis and the intricate dance of chemical interactions.

Synonyms
2-Methyl-3-hydroxy-4-aminomethyl-5-acetylthiomethylpyridin