sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate

Identification

Molecular formula

C₁₃H₁₇NO₄S

CAS number

85263-32-1

IUPAC name

sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate

State

sec-Butyl 3-(2-sulfamoylphenyl)prop-2-enoate is solid at room temperature. It is stable under normal conditions and does not evaporate rapidly.

Melting point (Celsius)

89.00

Melting point (Kelvin)

362.15

Boiling point (Celsius)

314.00

Boiling point (Kelvin)

587.15

General information

Molecular weight

270.35g/mol

Molar mass

270.3480g/mol

Density

1.2500g/cm³

Appearence

sec-Butyl 3-(2-sulfamoylphenyl)prop-2-enoate appears as a white crystalline solid. It has a sharp, distinct chemical odor characteristic of chemical esters and sulfamoyl groups.

Comment on solubility

Solubility of sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate

The solubility of sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate can be influenced by several factors related to its chemical structure. This compound features a sulfonamide moiety, which can engage in hydrogen bonding, greatly affecting its interactions with solvents.

Key points about its solubility include:

Polarity: The presence of the sulfonamide group can increase the polarity of the molecule, enhancing its solubility in polar solvents such as water.
Solvent Interaction: The solubility may vary when dissolved in organic solvents like ethanol or acetone due to differing degrees of hydrogen bonding and dipole interactions.
pH Sensitivity: The solubility of sulfonamides can also be pH-dependent, with variations in ionization affecting how well the compound dissolves in the solution.

To sum up, understanding the solubility of sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate is essential for its applications and can be summarized by the quote: "Like dissolves like". This principle serves as a guiding concept for predicting its behavior in various solvents.

Interesting facts

Interesting Facts about sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate

sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate is an intriguing compound that has drawn attention for its potential applications in medicinal chemistry. This compound features a unique structure that incorporates a sulfamoyl group, which significantly enhances its biological activity. Here are some fascinating details:

Pharmaceutical Potential: The incorporation of the sulfonamide group in the structure makes this compound a candidate for anti-inflammatory and antimicrobial properties. The sulfamoyl moiety is known for its role in various drug actions.
Synthesis Approaches: The synthesis of this compound often involves Michael addition reactions, providing a valuable example of how functional groups can be effectively introduced into organic frameworks.
Importance in Drug Design: Compounds like sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate serve as pivotal platforms in the design of more complex pharmaceuticals, showcasing how small modifications can lead to varying biological effects.
Structure-Activity Relationship (SAR): Investigating SAR can illuminate how the presence of the sulfamoyl group influences pharmacodynamics and pharmacokinetics, vital for optimizing therapeutic efficacy.

The study of sec-butyl 3-(2-sulfamoylphenyl)prop-2-enoate exemplifies the dynamic nature of organic chemistry and its capacity to innovate in drug development. It's a testament to how a seemingly simple molecule can harbor complex interactions within biological systems, paving the way for future research and therapeutic breakthroughs.