Nalidixic Acid Sodium Salt | Solubility of Things

Identification

Molecular formula

C₁₂H₁₁N₂NaO₃

CAS number

3374-05-8

IUPAC name

sodium;1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate

State

At room temperature, nalidixic acid sodium salt is in a solid state, typically the form of crystalline powder.

Melting point (Celsius)

225.00

Melting point (Kelvin)

498.00

Boiling point (Celsius)

637.60

Boiling point (Kelvin)

910.80

General information

Molecular weight

280.26g/mol

Molar mass

280.2630g/mol

Density

1.3400g/cm³

Appearence

Nalidixic acid sodium salt typically appears as a white to yellowish-white crystalline powder. It is odorless and may exhibit slight hygroscopic properties, meaning it can absorb moisture from the environment.

Comment on solubility

Solubility of Sodium 1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate

The solubility of sodium 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate can be influenced by several factors due to its unique chemical structure. Here are some key points to consider:

Polarity: This compound contains both polar and nonpolar functional groups, which can affect how well it interacts with water and other solvents.
pH Dependence: Its solubility may vary with changing pH levels. Salts typically have improved solubility in more acidic or basic environments.
Temperature Influence: Increasing temperature may enhance the solubility of the compound in aqueous solutions, as is often the case with many organic salts.
Solvent Specificity: It is likely to exhibit higher solubility in polar solvents, with water being the primary solvent of interest, compared to nonpolar solvents.
Ionization: Being a sodium salt, it is expected to dissociate into ions, which generally increases solubility in polar solvents.

In conclusion, while the exact solubility of sodium 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate may vary, one can anticipate that the compound would demonstrate acceptable solubility in aqueous solutions under appropriate conditions due to its ionic nature.

Interesting facts

Interesting Facts about Sodium 1-Ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate

Sodium 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate is a fascinating compound that showcases a unique blend of organic chemistry and medicinal applications. Here are some intriguing aspects of this compound:

Structural Diversity: This compound belongs to a class of heterocyclic compounds known as naphthyridines. Its structure consists of a fused ring system that enhances its potential biological activity.
Biological Significance: Compounds related to naphthyridine have been studied for their pharmacological properties, including antimicrobial, anti-inflammatory, and anticancer activities, making them valuable in drug design.
Research Applications: Sodium 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate has potential utility in medicinal chemistry due to its structural motifs, which may lead to the development of novel therapeutic agents.
Solubility Enhancer: The presence of the sodium ion not only contributes to the solubility of the compound in aqueous solutions but also impacts its bioavailability, making it easier for biological systems to absorb.
Environmental Impact: Research into the environmental fate of naphthyridine derivatives is essential, as their biodegradability and effects on ecosystems need to be understood for sustainable use.

In conclusion, sodium 1-ethyl-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylate is a compound that not only stands out due to its structural complexity but also due to its wide range of applications and significance in scientific research. As we continue to explore the properties of such compounds, their role in advancing healthcare and environmental safety becomes increasingly important.