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Naproxen sodium

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Identification
Molecular formula
C14H13NaO3S
CAS number
26159-34-2
IUPAC name
sodium;1-hydroxy-2-oxo-2-[4-(2-phenylethyl)phenyl]ethanesulfonate
State
State

Naproxen sodium exists as a solid at room temperature.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
285.00
Boiling point (Kelvin)
558.15
General information
Molecular weight
252.24g/mol
Molar mass
252.2410g/mol
Density
1.1970g/cm3
Appearence

Naproxen sodium is typically a white to creamy, crystalline powder. It is odorless and has a bitter taste.

Comment on solubility

Solubility of Sodium; 1-Hydroxy-2-oxo-2-[4-(2-phenylethyl)phenyl]ethanesulfonate

The solubility of sodium; 1-hydroxy-2-oxo-2-[4-(2-phenylethyl)phenyl]ethanesulfonate can be affected by several factors that dictate how well it dissolves in various solvents. Here are some key aspects to consider:

  • Polar vs. Non-Polar Solvents: Solubility generally increases in polar solvents due to the hydrophilic nature of the sulfonate group. Thus, it is more likely to dissolve in water than in organic solvents.
  • Concentration Impact: The saturation point of this compound in solution can vary significantly based on temperature and the presence of other solutes.
  • Temperature Effects: Elevating the temperature usually enhances solubility, as increased kinetic energy helps to disrupt intermolecular interactions.
  • pH Levels: The solubility may also be influenced by the pH of the solution, with variations affecting the ionization of the sulfonate group.

It's essential to keep in mind that “like dissolves like,” meaning that the chemical nature of the solvent will play a crucial role in solubility outcomes. The presence of specific functional groups may enhance or hinder interaction with solvents, which creates a unique behavior in the solubility of this compound.

In conclusion, understanding the solubility of sodium; 1-hydroxy-2-oxo-2-[4-(2-phenylethyl)phenyl]ethanesulfonate requires a comprehensive view of its chemical structure and the environmental conditions it is placed in.

Interesting facts

Exploring Sodium; 1-Hydroxy-2-oxo-2-[4-(2-phenylethyl)phenyl]ethanesulfonate

Sodium; 1-hydroxy-2-oxo-2-[4-(2-phenylethyl)phenyl]ethanesulfonate, commonly referred to simply as a sulfonate derivative, embodies a fascinating intersection of organic chemistry and biochemistry. This compound exhibits intriguing properties that make it particularly useful for a variety of applications.

Interesting Facts:

  • Biological Relevance: This compound plays a significant role in biological systems, often serving as a building block in the synthesis of more complex biomolecules.
  • Pharmaceutical Applications: Due to its hydroxy and sulfonate functional groups, it is explored for potential pharmaceutical applications, particularly in the development of drugs that can impact biological pathways.
  • Versatile Reactivity: The presence of both ketone and sulfonate groups equips this compound with versatile reactivity, enabling it to undergo various chemical transformations, which is a boon for synthetic chemists.
  • Research Tool: In research settings, it may be utilized as a reagent for studying enzyme kinetics or cellular processes, highlighting its utility beyond just a compound with a specific formula.
  • Structure-Activity Relationship: The specific arrangement of the phenethyl and phenyl groups lends insight into structure-activity relationships, prompting further investigation into how subtle changes can affect biological activity.

In summary, sodium; 1-hydroxy-2-oxo-2-[4-(2-phenylethyl)phenyl]ethanesulfonate is more than just a chemical entity; it serves as a bridge between theory and application in the realms of chemistry and biology. As researchers continue to explore its properties, the potential for new discoveries remains vast.