Sodium cholesteryl sulfate | Solubility of Things

Identification

Molecular formula

C₂₇H₄₅NaO₄S

CAS number

4180-23-8

IUPAC name

sodium;(13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) sulfate

State

At room temperature, sodium cholesteryl sulfate is typically found in a solid powdered form.

Melting point (Celsius)

185.00

Melting point (Kelvin)

458.15

Boiling point (Celsius)

0.00

Boiling point (Kelvin)

0.00

General information

Molecular weight

464.67g/mol

Molar mass

464.6690g/mol

Density

1.1800g/cm³

Appearence

The compound appears as a white to off-white powder. It is often used in its powder form for various biochemical applications.

Comment on solubility

Solubility of Sodium (13-Methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) Sulfate

The solubility of sodium (13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) sulfate, given its structural complexity, can be influenced by several factors:

Ionic Nature: As a sodium salt, the compound is likely to be soluble in polar solvents like water due to the breaking of ionic bonds upon interaction with water molecules.
Alkyl and Carbon Framework: The presence of the methyl and cyclopenta[a]phenanthren framework may introduce hydrophobic characteristics that could limit solubility to some extent.
Temperature Dependency: Generally, an increase in temperature tends to enhance solubility for solids, suggesting that heating may be beneficial in achieving higher dissolution rates.
pH Influence: Changes in pH could affect the ionization state of the sulfate group, potentially altering solubility characteristics.

In summary, while sodium (13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) sulfate may be generally soluble in water, factors such as its complex structure and environmental conditions greatly impact its solubility. It is essential to consider these aspects when predicting behavior in various solutions.

Interesting facts

Interesting Facts about Sodium (13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) Sulfate

The compound sodium (13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) sulfate holds a unique position in both organic synthesis and medicinal chemistry. Here are some intriguing aspects of this compound:

Structural Complexity: This compound exhibits a complex molecular structure that includes both a steroid-like core and a sulfate group. Understanding its 3D configuration is essential for exploring its potential biological activities.
Biological Relevance: Compounds with similar backbones have been studied for their pharmacological properties. There is ongoing research into their efficacy as hormone analogs or potential therapeutic agents.
Modifications and Derivatives: The presence of a sulfate group introduces the possibility of various derivatization strategies, enhancing solubility and bioavailability for drug formulation. Chemists are continuously evaluating how modifications can impact the compound's interaction with biological targets.
Challenges in Synthesis: The synthesis of this compound likely involves numerous intricate steps. Challenges include achieving regioselectivity and maintaining yield during multi-step reactions, making it a captivating target for organic chemists.
Sulfate Functionality: The sulfate group is not only crucial for water solubility but also plays a significant role in biological recognition processes. The study of sulfated compounds is an expanding field in glycoscience.

In summary, sodium (13-methyl-17-oxo-9,11,12,14,15,16-hexahydro-6H-cyclopenta[a]phenanthren-3-yl) sulfate embodies a rich interplay of structure, reactivity, and potential uses that fascinates scientists and chemists alike. As research continues, we may uncover new pathways and applications that highlight the importance of this compound in both academic and industrial settings.