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Naproxen Sodium

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Identification
Molecular formula
C14H13NaO3
CAS number
26159-34-2
IUPAC name
sodium;2-(1-naphthyl)-3-(2-thienyl)propanoate
State
State

Naproxen sodium is typically a solid at room temperature. It is often provided in the form of tablets or capsules for oral use.

Melting point (Celsius)
255.00
Melting point (Kelvin)
528.15
Boiling point (Celsius)
235.00
Boiling point (Kelvin)
508.15
General information
Molecular weight
252.24g/mol
Molar mass
252.2410g/mol
Density
1.1000g/cm3
Appearence

Naproxen sodium appears as a white to creamy white, crystalline powder that is often odorless. It is posited in a range of medical applications primarily due to its non-steroidal anti-inflammatory properties.

Comment on solubility

Solubility of Sodium 2-(1-Naphthyl)-3-(2-Thienyl)propanoate

Sodium 2-(1-naphthyl)-3-(2-thienyl)propanoate, a complex organic salt, exhibits notable solubility characteristics.

To understand its solubility behavior, consider the following aspects:

  • Polar Nature: As a sodium salt, it benefits from the ionic nature of the sodium (Na+) ion, which enhances its solubility in polar solvents, particularly water.
  • Hydrophobic Contributing Factors: The presence of the naphthalene and thienyl groups introduces substantial hydrophobic characteristics, which can limit solubility in less polar solvents.
  • Temperature Dependence: It is generally observed that solubility increases with temperature, meaning that higher temperatures can enhance the dissolution of this compound in aqueous solutions.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solution, which could affect the ionization and thus the overall solubility of the compound.

In summary, while sodium 2-(1-naphthyl)-3-(2-thienyl)propanoate displays good solubility in polar solvents like water, its solubility behavior is affected by its unique structure and the environmental conditions. This dual nature makes it an intriguing compound in the realm of chemistry.

Interesting facts

Interesting Facts about Sodium 2-(1-Naphthyl)-3-(2-thienyl)propanoate

Sodium 2-(1-Naphthyl)-3-(2-thienyl)propanoate is a fascinating compound in the realm of organic chemistry, particularly due to its unique structure and potential applications. Here are some interesting aspects of this compound:

  • Structural Diversity: This compound features a complex structure that integrates components from both naphthalene and thiophene, which contributes to its intriguing chemical properties.
  • Pharmaceutical Potential: Compounds with naphthalene and thiophene moieties are often explored for their biological activities. Sodium 2-(1-Naphthyl)-3-(2-thienyl)propanoate could hold promise in medicinal chemistry.
  • Synthesis: The synthesis of this compound demonstrates the efficiency of modern organic chemistry techniques, employing methodologies such as coupling reactions and esterification.
  • Applications: Due to its unique properties, it may be researched for applications in materials science, particularly in developing organic semiconductors or sensors.
  • Chemical Behavior: Understanding the reactivity of this compound can provide insights into its electronic structure, which is pivotal for any further applications in organic synthesis.

In summary, sodium 2-(1-naphthyl)-3-(2-thienyl)propanoate embodies the principles of structural versatility and functional potential. Its continuing study could pave the way for novel discoveries in both pharmaceutical and synthetic chemistry. As the famous chemist Linus Pauling once said, "The best way to have a good idea is to have a lot of ideas." This compound is a perfect example of how combining different chemical building blocks can lead to innovative structures and properties.