Dexamethasone sodium phosphate | Solubility of Things

Identification

Molecular formula

C₂₂H₂₈FNa₂O₈P

CAS number

55203-24-2

IUPAC name

sodium;[2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] hydrogen phosphate

State

At room temperature, dexamethasone sodium phosphate is a solid compound, usually encountered in its salt form, allowing it to dissolve in water easily for medical applications.

Melting point (Celsius)

233.00

Melting point (Kelvin)

506.00

Boiling point (Celsius)

300.00

Boiling point (Kelvin)

573.00

General information

Molecular weight

516.40g/mol

Molar mass

516.4040g/mol

Density

1.4330g/cm³

Appearence

Dexamethasone sodium phosphate typically appears as a white or almost white, crystalline powder. It is odorless and hygroscopic.

Comment on solubility

Solubility of Sodium [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] Hydrogen Phosphate

The compound sodium [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] hydrogen phosphate exhibits unique solubility characteristics that can significantly influence its applications in various fields.

Solubility in Water: Generally, sodium salts tend to be more soluble in water. However, the complex structure of this specific phosphate compound may alter its solubility profile.
Influence of pH: The solubility may depend on the pH of the solution, as certain functionalities in the compound are more soluble under acidic or basic conditions.
Polarity Considerations: Given the presence of hydroxyl (-OH) groups, the compound may exhibit increased polarity, potentially enhancing its solubility in polar solvents.
Hydrophobic Interactions: The substantial hydrocarbon portion of the molecule may also lead to limited solubility in purely aqueous environments, as its hydrophobic characteristics can hinder dissolution.

In summary, while sodium salts are typically soluble, the unique structural attributes of this compound suggest a nuanced solubility behavior influenced by various factors such as pH, polarity, and hydrophobic interactions. Understanding these aspects is crucial for predicting its behavior in biological and chemical systems.

Interesting facts

Interesting Facts about Sodium [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] Hydrogen Phosphate

This compound presents a fascinating intersection of organic chemistry and biochemistry, particularly with its dual identity involving both sodium and a complex organic moiety. Here are some intriguing points to consider:

Sodium Component: Sodium is a vital element in human physiology, playing a key role in maintaining fluid balance, nerve transmission, and muscle function. It is an essential electrolyte, which means it must be obtained through diet.
Structural Complexity: The compound's structure, characterized by its multiple functional groups, emphasizes the intricate nature of organic compounds. The presence of hydroxy groups suggests potential for hydrogen bonding, impacting solubility and reactivity.
Biochemical Relevance: The presence of phosphate groups in the compound suggests its potential biological significance. Phosphates are critical in energy transfer, especially in the form of adenosine triphosphate (ATP), and they influence many metabolic pathways.
Pharmacological Potential: Given its structural features, this compound may have intriguing pharmacological properties. Compounds similar in nature often exhibit hormonal or therapeutic effects, making them of interest in drug development.
Research Applications: This compound might be studied for its potential use in biological assays or drug delivery systems. Its unique structure could allow for targeted therapy in treating certain diseases.

Quote: "Chemistry is like cooking, just don't lick the spoon!" This reminds us of the diverse roles chemical compounds play in our everyday lives, often beyond our immediate perception.

Overall, sodium [2-(11,17-dihydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl] hydrogen phosphate provides a wealth of opportunities for study and application in both chemistry and medicine.